动脉粥样化的

MiR-217 is expressed in human atherosclerotic lesions and is negatively correlated with SirT1 expression and with FoxO1 acetylation status.

在人类动脉粥样硬化斑块中也有miR-217的表达，这一表达也与SirT1的表达以及Fox01的乙酰化状态呈负相关。

Methods and Results— Using a micro–single-photon emission computed tomography small-animal imaging system and a Food and Drug Administration–approved radiotracer ([indium 111] oxyquinoline, 111In-oxine), we demonstrate here that monocyte recruitment to atherosclerotic lesions can be visualized in a noninvasive, dynamic, and 3-dimensional fashion in live animals.

方法和结果——采用微单光子发射计算机断层摄影术的小动物成像系统和美国食品药品治理局认同的放射性示踪剂（111In-oxine），我们证实动物体内单核细胞向动脉粥样硬化损害处的聚集能够通过一种非侵入性，动态的，3维方式进行可视化观察。

Based on the observation that mammalian cells appear to be dependent on methylation for activation, SAHH has recently been selected as an attractive specific target for design of agents for immunosuppression, antiviral, treatment of atherosclerosis and Alzheimer's disease.

鉴于SAHH在调节生物体转甲基化反应中的核心地位，它已被选择作为多种新药研发的重要靶点，包括免疫抑制剂、抗病毒药、防治动脉粥样硬化和阿尔茨海默病药物。

Patients in later series had neither risk factors for osteonecrosis nor osteonecrosis at other extraskeletal sites; instead osteoporosis and significant cardiovascular morbidity/atherosclerosis was found in most of the patients.6,19,21 Other findings suggesting an ischemic etiology in these patients is absent enhancement on MRI of the affected vertebrae,7,15,20 "ischemic bone" noted intraoperatively,14 and vertebral body biopsies demonstrating reactive bone/fibrosis and occasionally osteonecrosis and hyalinized marrow.

以后病例系列中的患者既没有引起骨坏死的因素，在其它地方也没有出现骨坏死，而是骨质疏松症和显著的心血管疾病/动脉粥样硬化发病率[6，19，21]，其他的发现表明，在这些患者受影响的椎体上MRI不会出现增强影[7，15，20]，术中可看到&缺血性的骨块&[14]，椎体活检可看到有活性的骨/纤维化，有时可见骨坏死和玻璃样变[8，11，14，16，17，30，31]。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。