动脉狭窄

Types of the combination were as follows: ASD and VSD, 2 cases; ASD and PS, 2 cases; ASD and MS, 1 case; ASD and coronary artery stenosis, which needed interventional treatment, 1 case; VSD and PDA, 3 cases; ASD and anomalous inferior vein cava drainage, 1 case; PDA and B-preexcitation syndrome, 1 case; PDA and dextrocardia, anomalous inferior vein cava drainage, 1 case.

复合类型为：房间隔缺损合并室间隔缺损2例，ASD合并肺动脉瓣狭窄2例，ASD合并二尖瓣狭窄1例，ASD合并冠脉狭窄需介入治疗1例，ASD合并右位心1例，VSD合并动脉导管未闭3例，PDA合并B型预激综合征1例，PDA右位心、下腔静脉肝段缺如1例，VSD合并下腔静脉肝段缺如1例。

place the 8f carotid sheath in carotid, and expand stenosis by sacculus first, let bypass through the stenosis and released.

8f动脉鞘置入颈总动脉，预扩张球囊通过狭窄部位行预扩张，支架在导丝支撑下通过狭窄部位，回撤外鞘将支架释放。

Results Critical stenosis or occlusion of contralateral arteries were found in the siphonic part of internal carotid artery in 6 patients, terminal ICA or proximal middle cerebral artery in 6 patients, and distal MCA in 1 patient. Seven patients had proximal ICA occlusion. The brain MRI showed typical watershed cerebral infarctions in 8 patients.

结果 所有患者均存在对侧颅内外血管严重狭窄或闭塞，其责任血管分布：颈内动脉虹吸段6例；颈内动脉末端或大脑中动脉起始部6例；大脑中动脉的M2段1例；颈内动脉起始部7例。8例头颅磁共振显示典型的分水岭脑梗死。6例行血管重建治疗，临床未再发作。

The incidence of lower extremity atherosclerotic plaque, arterial steno- sis and obliterlation of type Ⅱ diabetes in old age was apparently higher than that of control group. The incidence of atherosclerotic plaque was mainly involved in femoral and popliteal artery. While the incidence of stenosis and obliterlation were mainly involved in the distal arteries below popliteal artery, especially, anterior tibial artery, posterior tibial artery and pedis dorsal artery.

结果 糖尿病患者下肢动脉血管管腔的硬化斑块、狭窄和闭塞的发生率明显高于对照组；硬化斑块的发生率以股动脉及腘动脉最为常见，而管腔狭窄、闭塞率以及腘动脉以下的远端动脉血管最为明显。

Results］ There were 12 stenosises in the 12 patients (4 in innominate artery and 8 in proximal left subclavian artery).

结果］ 锁骨下动脉窃血12例患者中，共12处狭窄（无名动脉4处，左侧锁骨下动脉起始部8处）。

The former studies have shown Concentrated Xuefu Zhuyu Pill have effects on many pathological factors of restenosis, such as platelet agregation and adhesion, SMC proliferation,and it can prevent restenosis after PTA (percutanous transluminal angioplasty) of experimental illac artery AS of New Zealand rabbits.

因此，在动物实验证明血府逐瘀浓缩丸具有抗动脉粥样硬化，抑制AS家兔血管SMC增生作用，以及在防治家兔动脉粥样硬化PTA后再狭窄方面有一定作用的基础上，我们开展了其对冠心病人PTCA后再狭窄的防治研究。

Plasma Ang Ⅰ and Ang Ⅱ levels, chymase mRNA levels, arteries' PCNA positive percents and the thickness of carotid artery were measured.

通过测定血浆Ang Ⅰ及AngⅡ住水平、糜酶 mRNA表达水平、颈动脉细胞增殖核杭原阳性率及颈动脉各层厚度观察曲尼司特对犬颈动脉损伤后狭窄的作用。

Objective To study the relationship of endangium proliferation and the expression of metalloproteinases and tissue inhibitors of metalloproteinases after angioplasty of iliac artery in rabbits to investigate the probable mechanism of composite Danshen pill in prevention and treatment of restenosisMethods 30 white male rabbits of Japan （the average body weight was 25～30 kg）were randomly divided into 3 groups:normal control group,model group (intima destroyed by balloon and given hypercholesterol diet),CDP group (intima destroyed by balloon and given hypercholesterol diet plus drug CDP 150 mg/d),10 ones each groupResults The results of iliac artery angiogram and the analysis of pathology:there were lumens stenosis,thinner intima,smaller intima area,in CDP group compared with those in model group,and ratio of intima and tunica media thickness and area among each group (P＜001)Immunohistochemistry analysis:the MMP2,MMP9,TIMP1,TIMP2 in model group significantly increased than those in control group (P＜001)The CDP group had lower MMP2 and MMP9 expression,higher TIMP1 and TIMP2 expression,and increased MMP2/TIMP1,MMP9/TIMP2 than model group (P＜001)The thickening of vascular neointima and stenosis degree of vascular lumen were relevant to MMP2 and MMP9 (r=0896,P＜001)Conclusions MMP and TIMP play the very important role in the restenosis process of arteryCDP could inhibit the thickness of vascular neointima after balloon injury,the probable mechanism of which may be inhibiting collagen formation,smooth muscle immigration and decreasing hyperplasia of intima by interfering expression of MMPs and TIMPs

目的 研究兔髂动脉成形术后血管内膜增生和基质金属蛋白酶及其抑制物表达之间的关系，探讨复方丹参滴丸预防再狭窄的可能机制。方法健康成年二级雄性日本大耳白兔30只，平均体重25～30 kg。随机分为3组：正常对照组10只，模型组10只（球囊内膜剥脱加高胆固醇饮食），治疗组10只（球囊内膜剥脱加高胆固醇饮食以及复方丹参滴丸150 mg/d）。结果兔髂动脉造影、血管病理图像分析检测结果：①复方丹参滴丸组较模型组血管造影示管腔直径狭窄、内膜厚度减少、内膜面积减少、内膜厚度和中膜厚度比、面积比，各组之间有显著性差异(P＜001)。②免疫组化分析：模型组MMP2、MMP9、TIMP1、TIMP2表达均高于对照组（P＜001）；复方丹参滴丸组MMP2、MMP9的表达低于模型组，而TIMP1、TIMP2的表达高于模型组；TIMP1/MMP2、TIMP2/MMP9明显增加，差异有显著性（P＜001）。③内膜的增生以及管腔的狭窄程度与MMP2、MMP9有很好的相关性(r=0896，P＜001)。结论 MMP和TIMP在再狭窄形成中起重要作用；复方丹参滴丸能够明显抑制血管损伤后的内膜增生，可能的机制是通过影响金属蛋白酶MMP2、MMP9及其抑制物TIMP1、TIMP2的表达从而抑制胶原的生成、平滑肌的迁移、增生，而减少内膜的增生。

Methods:Percutaneous transluminal renal angioplasty with stent was performed on 203 consecutive patients with severe renal artery stenosis, caused by atheroma (123),arteritis (62) and fibromuscular displasia (18),for poorly controlled hypertension or preservation of renal function,who subsequently underwent 6 -month clinical follow-up for the effect of the procedure on renal f...

1999年至2004年，我院连续203例肾动脉严重狭窄的患者，其中男性128例(63.1％)，女性75例(36.9％)，年龄13-82(54±18)岁，病因分别为动脉粥样硬化123例(60.6％)、大动脉炎62例(30.5％)和纤维肌性结构不良18 例(8.9％)，因严重高血压或伴有肾功能不全而进行了肾动脉支架置放术，并随诊6个月，观察手术对患者血压、肾功能的影响。

MSCTA showed stenosis and obstruction of internal carotid artery, anterior cerebral artery and middle cerebral artery, including thirteen cases with bilateral and 6 cases with single lateral. There appeared abnormal vessels looked like smog on cerebral bottom. More than one branches of collateral artery could be seen in most of them. Sacculated aneurysm of lenticulostriate artery was shown in one patient. Five patients who were performed both MSCTA and DSA displayed similar above-mentioned vascular lesions.

MSCTA均清晰显示不同程度颈内动脉虹吸段、大脑前动脉及大脑中动脉起始段狭窄、闭塞，双侧病变者13例（68.4%），单侧病变者6例（31.6%）；脑底部见纤细迂曲的&烟雾&状异常血管网；大多可显示1支以上侧支动脉；1例显示右侧豆纹动脉囊状动脉瘤。5例同时行MSCTA与DSA者，均很好显示了上述血管病变。

The reasons of iron ions content overproof in grade Ⅱ desalting water system,such as variation water quality,contamination of regenerant , operation adjustment of pretreatment system and switching operation of bed were discussed.

对二级脱盐水系统中铁离子含量超标的原因，如来水水质发生波动、再生剂受到污染、预处理系统操作调整、床体运行切换等进行了论述。

You were hired to drum up new business, so go and do it.

公司雇你招徕新业务，你就做你的事好了。