动脉内膜

Objective To understand the clinical application of cisplatin internal iliac artery infusion for uterine cancer treatment.

目的 探讨术中髂内动脉注射顺铂治疗子宫内膜癌和子宫颈癌的临床应用可行性。

AIM: To investigate the effects of fluvastatin on intimal hyperplasia following balloon injury of rabbit iliac artery.

目的：探讨兔髂动脉急性损伤后，氟伐他汀对血管内膜增殖的抑制作用及机制。

The protection of the cardiovascular: atherosclerosis in the occurrence and development of the process, vascular intimal oxidation of LDL is a key element.

保护心血管：在动脉粥样硬化的发生和发展过程中，血管内膜中的脂蛋白氧化是一个关键因素。

Objective: To evaluate the influence of local delivery of tissue factor pathway inhibitor gene on intimal hyperplasia after balloon injury.

目的： 研究组织因子抑制子基因局部转移对兔颈总动脉损伤后内膜增生的影响。

Resident intimal dendritic cells accumulate lipid and contribute to the initiation of atherosclerosis.

内膜处的树突状细胞能够蓄积脂质并且在动脉粥样硬化的起始阶段具有作用。

We measured the intimal plus medial thickness in carotid common arteries also.

我们同时测量颈总动脉的内膜加中膜厚度。

Especially, recent re-searches show that UCP2 participates in the process of energy metabolism, the creation of ROS, the deqeneration of endometrium and caducity and so on. It also has relation with nonspirituous hepatic adipose infiltration, obesity, atherosclerosis, ischemia, reperfusion injury and the type 2 diabetes mellitus, so it has aroused world attention.

特别是近年来的研究发现，UCP2参与了能量代谢、ROS的产生、子宫内膜退化、衰老等过程，并且与非酒精性脂肪肝、抗肥胖、动脉粥样硬化、局部缺血以及缺血再灌注损伤和2型糖尿病等有一定的相关性，倍受人们的关注。

There are four kind of isoforms of endothelin in human and other mammals named ET-1, ET-2, ET-3 and ET-β, which are slightly different in construction and pharmacological effect. In human beings, ET-1 is the dominative subtypes. ET-1 remains in blood at a low level about 5ng per liter on physical state. It is synthesized, stored, released and metabolized locally. The half-life of ET-1 is about 1 hour. ET-1 is the most potent vasoconstrictive factor till now, and it is more functional in vein than in artery. In vascular bed, there are two kind of ET receptors. Type A mainly located in smooth muscle cells, whereas type B in endothelial cells. The latter can stimulate intimal hyperplasia via a parasecretion way and activate some oncogenes such as c-fos and c-myc and then enhance their expression. These alterations result in constriction of blood vessels, thus the SMC steps into proliferate state from silent state.

人及哺乳动物体内有四种结构及药理学性质略有差异的异物体，分别为ET-1、ET-2、ET-3、ET-β，而在人主要是ET-1，在生理条件下，ET-1在血浆中含量较低，约为5ng〓，故ET-1不是一个循环激素，而是局部合成释放，局部起作用的活性物质，半衰期约1小时，ET-1是目前已知的最强的血管收缩剂，对静脉的作用比动脉强，在血管床，ET受体有A、B两型，A型主要分布在平滑肌细胞，B型主要分布在内皮细胞，它可以通过旁分泌途径刺激内膜增生，具有有丝分裂原效应，可以激活某些癌基因如C-fos、C-myc使其表达增强引起血管收缩，使静止期SMC进入增殖期，还可以通过信号传导途径，与bFGF、GTF-β、PDGF等生长因子协同作用，起共有丝分裂原作用。

Objective: The purposes of the present study are as follows: 1 To study the effect of direct contact with VSMC on transdifferentiation of MSC; 2 To construct MSC of Dual-stable expression of AT2R gene medicated by tetracycline regulatable system.; 3 To investigate the effects of AT2R gene medicated by tetracycline regulatable system on neointimal hyperplasia in rat carotid arteries after balloon angioplasty.

本实验体外观察MSC与VSMC在直接接触培养下的分化情况，并以MSC为载体，通过体外细胞基因转染及筛选，获得双重稳定受到强力霉素调控表达AT2R基因的MSC，将此受到调控表达的AT2R基因导入大鼠颈动脉球囊损伤动物模型中，观察MSC细胞移植实现AT2R基因在体可调控表达在新生内膜中形成的作用及潜在意义。

Results The average cross section area, maximum diameter and minimum diameter of spiral arterioles in both spongeous and dense layers of endometrium increased significantly after insertion of TCu 220C IUD.

取9例放置γCuI IUD妇女、10例放置TCu 220C IUD妇女(TCu 220C组)及10例放置前妇女的晚泌期子宫内膜，连续切片，HE染色后，光镜下对螺旋动脉行形态计量学分析。

I am accused of being overreligious," she said in her quiet, frank manner,"but that does not prevent me thinking the children very cruel who obstinately commit such suicide.""

客人们在卡罗利娜·埃凯家里，举止就文雅一些，因为卡罗利娜的母亲治家很严厉。

Designed by French fashion house Herm è s, this elegant uniform was manufactured in our home, Hong Kong, and was the first without a hat.

由著名品牌 Herm è s 设计，这件高贵的制服是香港本土制造，是我们第一套不配帽子的制服。