动脉内膜

Think at present, cause the main and immediate cause with heart disease and apoplectic head, arteriosclerosis, it is long the result of accumulate over a long period of injury of the film inside artery.

目前认为，造成心脏病和脑中风的主要直接原因—动脉硬化，是长时间动脉内膜损伤日积月累的结果。

Results In diabetic group, the IMT was thicker than that in non-diabetic group (P.01), and the arteriosclerotic plaque was observed in 90% patients .

结果 糖尿病组较非糖尿病组动脉内膜增厚（P.01），动脉硬化斑块发生率90％。

It also gives opportunities to the patients with contraindication to carotid artery endarterectomy.

实验证实，其对卒中二级预防的效果与经典的颈动脉内膜切除术相同。

METHODS: Endarterium was injuried and coronary thrombi were formed gradually through direct electrical stimulation on the coronary artery of Chinese experimental miniature swine.

直接电刺激中国实验小型猪冠状动脉造成动脉内膜损伤，逐渐形成冠脉内血栓。

Results: The tHey and blood fat level in blood plasma and expression of MCP-1mRNAof aorta on model group is obviously higher than that of control group (P＜0.05);the result of immunohistochemistry shows that the expression of VCAM-1 and MMP-2enhanced, Bcl-2 is lower; aorta slice shows endarterium discontinuation, strippingpartly, smooth muscle cell arrange puffly and chaotic, infiltration of lipoid ofdifferent degree are observed in aorta wall, pathological changes suffusion, morexanthoma cell, plaque protrude lumens. The they and blood fat level in blood plasmaand expression of MCP-lmRNA, VCAM-1, MMP-2 of aorta on intervention group aremuch lower than that of model group (P＜0.05); Bcl-2 of intervention group isstrengthened, and the pathomorphology and immunohistochemistry of aorta showpathological changes are slighter than model group.

结果：模型组，血浆中同型半胱氨酸浓度、血脂水平、主动脉MCP-1mRNA表达显著高于正常对照组(P＜0.05)，免疫组化示主动脉内皮细胞VCAM-1、MMP-2表达增强，Bcl-2表达降低；主动脉切片发现动脉内膜不连续，部分剥脱，平滑肌细胞排列疏松、紊乱，主动脉壁均见到程度不同的脂质浸润，其病变弥漫，泡沫细胞较多，可见斑块突出管腔；干预组，血浆中同型半胱氨酸含量、血脂水平显著低于对照组和模型组(P＜0.05)，主动脉MCP-1mRNA、VCAM-1、MMP-2表达显著弱于对照组和模型组(P＜0.05)，Bcl-2表达增强(P＜0.05)，主动脉病理形态学和免疫组织化学检测示病变轻于模型组。

Objective To explore the relationship between the plasm level of homocysteine and C-reaction protein level and carotic intimal-medial thickness in type 2 diabetes(T2DM).

目的 观察2型糖尿病患者血浆同型半胱氨酸和C反应蛋白与颈动脉内膜中层厚度的关系，探讨其对糖尿病患者并发动脉粥样硬化的发病机制及临床意义。

Objective To investigate the influence of glucose on the carotid intimal thickness and arterial stiffness in the old patients with hypertension.

目的 探讨老年高血压患者血糖变化对颈动脉内膜中层厚度和动脉弹性的影响是否有叠加作用。

There were significant differences between all the experimental groups and the control group (F=193.25, P＜0.01). Conclusions IL-1β and TNF-α induce a strong expression of MCP-1 mRNA and protein in HUVECs. Both cytokines may be involved in the atherogenesis by inducing the liberation of MCP-1 by endothelial cells and increasing the recruitment of monocytes into the subendothelial space.

IL-1β和TNFα均能显著增强内皮细胞MCP-1 mRNA和蛋白的表达，提示它们通过诱导内皮细胞产生MCP-1，吸引单核细胞迁入动脉内膜而参与动脉粥样硬化的发生和发展。

Among all persons who finished questionnaire 21.68% were resident physician,36.95% were attending physician, 25.65% were vice chief physician/chief physician; the most common cardiovascular disease in the investigated persons hospitals were angina (55.42%),stroke(38.17%), myocardial infarction(28.70%), heart failure (28.24%), hypertension (28.24%); as for early vascular disease detection methods,57.40% of investigated persons thought artery endothelial function examination,46.72% thought angiography, pulse wave velocity measurement and carotid intima-media thickness measurement were 40.61% and 31.76%;76.49% and 53.89% of the investigated persons thought angiotension converting enzyme inhibitor and statins could revert early vascular disease;96.79% of the investigated persons thought promotion early vascular disease detection strategy could help for reducing total burden of cardiovascular disease in our country;78.47% of the investigated persons thought early vascular disease detection methods should be easily used and non-invasive.

被调查者所在医院最常见心血管疾病顺序分别心绞痛55.42%，脑卒中38.17%，心肌梗死28.70%，心力衰竭28.24%，高血压28.24%；关于血管病变早期检测57.40%的被调查者认为通过动脉内皮功能测定，认为通过血管造影者占46.72%，认为通过脉搏波速度和颈动脉内膜中层厚度测定者分别占40.61%和31.76%；分别有76.49%和53.89%的被调查人群认为血管紧张素转换酶抑制剂和他汀类药物能够逆转早期血管病变；96.79%的被调查者认为推广血管病变早期检测技术有利于降低我国心脑血管疾病总体负担；78.47%的被调查者认为用于推广的早期血管病变检测技术应该是操作方便和无创伤。

Among all persons who finished questionnaire 21.68% were resident physician,36.95% were attending physician, 25.65% were vice chief physician/chief physician;the most common cardiovascular disease in the investigated persons hospitals were angina (55.42%),stroke(38.17%),myocardial infarction(28.70%),heart failure(28.24%), hypertension(28.24%);as for early vascular disease detection methods,57.40% of investigated persons thought artery endothelial function examination,46.72% thought angiography,pulse wave velocity measurement and carotid intima-media thickness measurement were 40.61% and 31.76%;76.49% and 53.89% of the investigated persons thought angiotension converting enzyme inhibitor and statins could revert early vascular disease;96.79% of the investigated persons thought promotion early vascular disease detection strategy could help for reducing total burden of cardiovascular disease in our country;78.47% of the investigated persons thought early vascular disease detection methods should be easily used and non-invasive.

被调查者所在医院最常见心血管疾病顺序分别为心绞痛55.42%，脑卒中38.17%，心肌梗死28.70%，心力衰竭28.24%，高血压28.24%；关于血管病变早期检测57.40%的被调查者认为通过动脉内皮功能测定，认为通过血管造影者占46.72%，认为通过脉搏波速度和颈动脉内膜中层厚度测定者分别占40.61%和31.76%；分别有76.49%和53.89%的被调查人群认为血管紧张素转换酶抑制剂和他汀类药物能够逆转早期血管病变；96.79%的被调查者认为推广血管病变早期检测技术有利于降低我国心脑血管疾病总体负担；78.47%的被调查者认为用于推广的早期血管病变检测技术应该是操作方便和无创伤。

I am accused of being overreligious," she said in her quiet, frank manner,"but that does not prevent me thinking the children very cruel who obstinately commit such suicide.""

客人们在卡罗利娜·埃凯家里，举止就文雅一些，因为卡罗利娜的母亲治家很严厉。

Designed by French fashion house Herm è s, this elegant uniform was manufactured in our home, Hong Kong, and was the first without a hat.

由著名品牌 Herm è s 设计，这件高贵的制服是香港本土制造，是我们第一套不配帽子的制服。