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动脉内膜

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In some areas arterioles were ruptured and subendocardial plexuses disappeared or ruptured.

有些区域可见小动脉破裂,心内膜下丛消失或血管破损。

The representative characteristic of the gland is that its intima and media are not ring form like those of general blood vessels but reculodromous and they extend to ducts cavity from different places and join each other to form tortuose reticulated vessels which have different shapes and sizes in diameter.

颈动脉腺的最大特点是中膜和内膜并不像一般血管形成环圈状,而是从不同部位向管腔突出延伸、相互连接构成大小不一、形状各异、迂回曲折的网状血管。

After administration of L-N〓-nitro-Arginine, a specific antagonist of NOS, it was found that the basal and stimulated NO release of blood vessels (aorta, internal carotid, renal and mensenteric artery) was decreased further. The increase of coronary blood flow stimulated by Ach was also reduced further, while the platelet aggregation degree and erythrocyte aggregation index increased significantly. Pathological examination indicated that aortic endothelium was destroyed, the blood vessels in cerebral, cardiac and renal tissues were hypertrophied further and some were almost occluded. The above fin dings resulted in SHR feeded with L-NNA having high incidence of stroke rate and high degree of renal cirrhosis when compared to control SHR. The infarct and hemorrhagic focuci in cerebral tissues, infarct focuci in cardiac tissues, atrophy and hyalinedegeneration of renal glomeruli and degeneration even necrosis of renal tubuli in renal tissues were al so found. The increase ratio of brain and heart to body weight and decrease ratio of kidney to body wei ght further demonstrated that the cerebral, cardiac and renal injuries were aggravated.

在上述结果的基础上进一步给予SHR NOS特异性拮抗剂左旋亚硝基精氨酸后,血管(胸主、颈内、肾及肠系膜动脉)NO基础释放及激动剂刺激释放进一步减少,Ach刺激冠脉流量的增加和胸主动脉内膜NOS活性也进一步减少,血小板聚集程度及红细胞聚集指数显著上升,病理切片显示胸主动脉内皮细胞破坏明显,脑心肾组织内的血管进一步增厚甚至几乎阻塞,导致饲L-NNA的SHR缺血性及出血性脑卒中发生率显著高于对照SHR,脑体重比显著升高;心肌内出现明显的缺血梗塞疤痕灶,心体重比显著升高;肾小球明显萎缩、玻璃样变性,肾小管也变性甚至坏死,使肾硬化程度显著增加呈颗粒性固缩肾,肾体重比也显著减少。

AIMS To grasp the basic pathology changes and clinical pathology of atherosclerosis, the primary hypertension, rheumatic disease, subacute infective endocarditis, valvular vitium of the heart.

教学目标 1。掌握动脉粥样硬化、高血压病、风湿病、亚急性感染性心内膜炎、心瓣膜病的病理变化和临床病理联系。

Diet-induced hyperhomocysteinemia can exacerbate intimal hyperplasia after denuding injury, making hyperhomocysteinemia a likely risk factor for postangioplasty restenosis.

高同型半胱氨酸血症能使球囊损伤后颈动脉新内膜增生恶化,预示高同型半胱氨酸血症可能是血管成形术后再狭窄的一个独立危险因素。

Objective To evaluate effect of hemagglutinating virus of Japan -liposome mediated tissue factor pathway inhibitor gene transfer on neointimal hyperplasia of endothelium denuded carotid artery of rat.

目的 探讨日本凝血病毒-脂质体介导的组织因子途径抑制剂基因转移对大鼠颈总动脉内皮剥脱术后新生内膜增生的抑制作用。

Results (1) The operation time:the mean time was (40.3±6.1) minutes.(2) pathological examinations: a few necroses in endometrium (2/15 cases) and shallow myometrium (12/15 cases).(3) According to the skin radiation measurements of 20 cases, the highest dose was found in sacrum projection(32.88cGy),came ovary(16.64cGy) and adrenal gland(16.64cGy) in the second and third. All the radiation doses was within the safe range in normal condition.(4) The collateral circulation from ovarian artery to uterus was confirmed by angiography and 3-D color Doppler imaging.

结果 (1)手术时间:平均(40.3±6.1)min;(2)病理检查:部分病例子宫内膜(2/15)、子宫浅肌层(12/15)出现少量的坏死,余未见异常;(3)患者术中所受X线辐射剂量:骶尾部皮肤处32.88cGy、卵巢16.64cGy 、肾上腺腰部皮肤投影处12.44cGy,均在正常安全剂量范围内;(4)侧支循环:经卵巢DSA造影及三维彩超证实术后卵巢动脉向子宫体提供少量的血流。

Results Separation of intimae was the most reliable criteria for diagnosis.The phenomenon of blood flow separation,artery dilation,intra-luminal thrombosis and so on were able to assist its diagnosis.

结果 内膜分离是本病最可靠的诊断依据,血流分隔现象、动脉扩张和管腔内血栓等具有重要的辅助诊断价值。

The fatty degeneration of liver cell was inhibited and the severity of atherosclerosis in heart muscle was improved.

内膜与中膜厚度比值,而且有抑制肝细胞的脂变程度和减轻心肌内小动脉粥样硬化的严重度。

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