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动脉内膜

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The inner diameter of carotid artery was measured at a different time: when there was no intervention, during reactive hyperemia of brachia artery and after sublingual administration with nitroglycerin.

以彩色多普勒超声检测颈动脉内膜-中层厚度,测定未受干预状态下、肱动脉反应性充血时及含服硝酸甘油后颈动脉内径。

The recipients were divided into three groups:allograft control group, allograft experimental group and isograft control group. After 60 days of transplant, vascular intimal thickness in all of the groups was observed by histological examination. The expression of PCNA and α-SMA was determined by immunohistochemistry.

动物分为3组:(1)异系移植对照组;(2)异系移植实验组;(3)同系移植对照组。60d后对移植动脉行病理组织学检测,观察移植动脉内膜增生程度,并行免疫组织化学染色检测移植动脉增殖细胞核抗原和平滑肌肌动蛋白的表达情况。

Results ① No intimal lesion was found in the transplant vessels of isograft group. In TA group,the proliferation of vascular smooth muscle cells was marked and abundant neocapillaries were observed in neointima. The thickness of intimal lesion of intervention group was 48.0% less than that of TA group.

结果 ①同系组移植动脉内膜未见增生;TA组内膜见大量的血管平滑肌细胞增殖,新生内膜中见丰富的新生毛细血管形成;干预组较TA组内膜增生程度减轻(P.05),内膜厚度减少48.0%。

METHODS: The models of abdominal aorta transplantation were made with micro-surgery in rats. The recipients were divided into three groups: allograft control group, atorvastatin-treated group and isograft control group. Vascular intimal thickness in all of the groups was observed by histological examination. The expression of proliferation cell nuclear antigenl and α-smooth muscle actin were determined by immunohistochemistry. The content of nitric oxide was measured by nitrate reductase chromatometry.

建立大鼠腹主动脉移植慢性排斥反应模型,分为3组:异系移植对照组、异系移植治疗组和同系移植组,60d后对移植动脉行病理组织学检测,观察移植动脉内膜增生程度;并行免疫组织化学染色,检测移植动脉增殖细胞核抗原和平滑肌肌动蛋白的表达情况,行硝酸还原酶比色法测定移植动脉组织NO的含量。

Objective To study the mechanism of monocyte recruitment in atherogenesis and to clarify the effect of monocyte chemotactic protein-1 (MCP-1) in this process.

目的 了解动脉粥样硬化发病过程中单核细胞粘附并进入动脉内膜的机制,分析单核细胞趋化蛋白-1(MCP-1)基因表达对单核细胞粘附动脉内膜的作用。

Methods: 1. Clinical study: 72 patients with hyperlipidemia and 45 patients with carotid atherosclerosis were divided into Xuezhikang group, Lovastatin group and blank group, the course of treatment was 6 months. To observe the effect on TC, TG, LDL-C, HDL-C, endothelium-dependent diastolic function of brachial artery, thickness of carotid plaque, Crouse integral and clinical symptoms.

1。临床研究,选取符合研究纳入病历标准的血脂异常患者72例及颈动脉粥样硬化患者45例,分别随机分为血脂康胶囊组、洛伐他汀组和空白对照组,疗程6个月,观察治疗前后血脂(TG、TC、LDL-C、HDL-C)、肱动脉内皮舒张功能、颈动脉内膜—中膜厚度、斑块积分及临床症状的变化。2。

The artery blood were sampled and iliac arteries were removed at 1,2,4,8 weeks after end...

发现血清中 TC、TG、L DL-C和内膜厚度、内膜/中膜厚度比随术后时间的延长而增加,动脉内膜厚度与 TC、TG、L DL-C的相关系数分别为 0 。8981、0 。8793、0 。86 82 (P 。0 1 )。

While carotid endarterectomy is performed in the emergency setting of an acute ischemic stroke that occurs postcarotid endarterectomy, emergency carotid endarterectomy is not generally done because there are concerns for complications of brain edema and hemorrhagic transformation due to reopening of the vessel and reperfusion of the stroke area.

很少有 &有效性的手术治疗急性缺血性中风的信息&虽然颈动脉内膜切除术是在急性缺血性中风发生 postcarotid 剥脱的紧急情况制定的,但紧急颈动脉内膜切除术一般不这样做,因为人们担心由于血管再通和缺血区域再灌注而致脑水肿和出血的并发症。

1.Preliminary studys on the carotid artery parameters Detected by Intracavitary Convex Array ProbePurpose and SignificanceFinal results of The North American Symptomatic Carotid Endarterectomy Trial and the MRC European Carotid Surgery Trial displayed that carotid artery must be observed intimately when stegnosis degree is higher than 50%and it must have an operation or interventional therapy in time when stegnosis degree is higher than 70%.

1、腔内凸阵超声探头检测颈动脉参数的初步研究目的和意义北美有症状颈动脉内膜剥脱试验(The North American Symptomatic CarotidEndarterectomy Trial NASCET)和欧洲颈动脉手术试验(European Carotid SurgeryTrial,ECST)研究结果显示,当颈动脉狭窄程度超过50%时要密切观察病情变化,当狭窄程度超过70%时要及时手术或介入治疗,治疗后可大幅降低脑梗死的发生率。

Among the earliest events in atherogenesis are the binding of monocytes to endothelium and their migration via the junctional spaces between endothelial cells till to the subendothelial spaces.

在高脂血等情况下,血液中的单核细胞不断粘附、进入动脉内膜并在内膜下聚集成为泡沫细胞是动脉粥样硬化发生发展过程中的重要环节。

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