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An O2-labile protein (hypoxia-inducible factor 1, HIF-1) has been identified that is hydroxylated and degraded under normoxic conditions but actie in hypoxia, where it enhances Epo gene transcription resulting in eleated hemoglobin leels and O2 capacity of the blood. The stimulation of Epo production at lowered arterial O2 tension can be maladaptie, if erythrocytosis deelops such as seen in high altitude habitants.

此途径因提高了体内血红蛋白水平,加强了epo基因转录和氧运输能力。epo 在动脉低氧情况下的产生使机体不适应--这种情况就如同世居高原人群中的细胞因子发生变化一样。

Objective to investigate the method and effect of endovascular therapy and surgery for subclavian artery occlusion disease.

目的 探讨腔内及手术治疗锁骨下动脉闭塞的方法和疗效。

PTA and stent implantation may be a first-line treatment for the patients with subclavian artery stenosis.

经皮球囊扩张治疗和支架植入术可以作为锁骨下动脉狭窄的一线治疗方法。

Objective To analyse the mutation types of the NOTCH3 gene with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy.

目的 分析伴皮质下梗死及白质脑病常染色体显性遗传性脑动脉病的NOTCH3基因突变类型。

Objective To investigate the clinical feature, differential diagnosis and treatment of posterior inferior cerebellar aneurysms.

目的探讨小脑后下动脉动脉瘤的临床特征、诊断、鉴别诊断和治疗。

Two cases of arteries were anastomosed each other into vascular network,which communicated with cutaneous vessel and deep fascial vascular network.

两组动脉沿神经干互相吻合成网,并与皮下及深筋膜下的血管网相交通。

The locational expression of MMP-9 of abdominal aortic aneurismal tissue of 20 patients was detected with immunohistochemical technique.

主要观察指标:基质金属蛋白酶9在3种不同动脉血管条件下的组织定位表达结果及表达水平。

In the pontocerebellar space, when CT plain scan were enhanced, the infarctional vessel obviously became thicken, which was reliable

例,CT 平扫见桥脑小脑间隙处一个长条环状血管影。增强时,其阻塞血管明显增粗、致密强化,这是诊断小脑前下动脉梗塞的

①Rat MSC and VSMC were cultured and identified, respectively. MSC were labeled with DAPI firstly, and then co-cultivated with VSMC. The changes of morphology and ultrastructure of co-cultured cells were observed. Immunfluorescence analysis was performed by using monoclonal antibodies against specific antigen.②We established the regulatable system in two steps: a stable MSC line expressing rtTA has been constructed and characterized firstly by transfected with pUHD 17-1hyg and then selected by hygromycin B; in a second step, this line was used for trandfer the AT2R gene to MSC to get the well establishing double stable MSC lines;③The expression of AT2R regulated by doxycycline was evaluated by western blot;④The MSCs were transduced into rat carotid arteries with regulatable AT2R gene after the establishment of rat carotid balloon injury restenosis model. The intimal/medial area ratio were measured by digital analysis system.

研究方法:(1)密度梯度离心法及胶原酶消化法分别培养原代大鼠MSC及VSMC,细胞共培养并行免疫荧光化学染色和透射电镜观察超微结构;(2)组成受Dox调控的哺乳动物表达系统的四种成分的转化、扩增及提纯并酶切鉴定;(3)采用常规分子生物学方法连续两个回合转染体外培养的MSC,并分别采用发光计检测不同细胞克隆萤光素酶活性改变以及RT-PCR方法检测AT2R目的基因mRNA表达情况,根据各个细胞克隆受Dox调控表达的程度,选择低背景、高诱导表达AT2R的细胞系,作为双重稳定MSC细胞系;蛋白免疫印迹法观察该细胞系在Dox调控下AT2R表达的时相性、持续性及在不同浓度Dox调控下的表达情况;(4)建立大鼠颈动脉球囊损伤动物模型,将双重稳定MSC在术中导入血管,分别于14 d、28 d进行病理切片,检测可调控AT2R对新生内膜增生的影响;采用RT-PCR免疫组织化学免疫荧光等技术观察AT2R基因在新生内膜中的表达以及细胞外基质成分表达的改变,TUNEL法检测血管组织中细胞凋亡的变化情况。

Alteration of supraorbital artery pulsation during lower body negative pressure exposure [J].

下体负压作用下眶上动脉脉搏的改变[J]。

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Breath, muscle contraction of the buttocks; arch body, as far as possible to hold his head, right leg straight towards the ceiling (peg-leg knee in order to avoid muscle tension).

呼气,收缩臀部肌肉;拱起身体,尽量抬起头来,右腿伸直朝向天花板(膝微屈,以避免肌肉紧张)。

The cost of moving grain food products was unchanged from May, but year over year are up 8%.

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However, to get a true quote, you will need to provide detailed personal and financial information.

然而,要让一个真正的引用,你需要提供详细的个人和财务信息。