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Results In the ANCA negative group, 2 cases were without malignant hypertension ,1 was acute tubular necrosis caused by herbs, 6 were scleroderma renal crisis, including 4 with renal biopsy, indicating hypertrophic arterial media, edema, thickened intima, onion- skin lesion in interlobular arteries and afferent arterioles, as well as ischemic lesion in glomeruli.

结果 11 例SSc急性肾损伤患者中,ANCA阴性9 例,6 例临床表现为硬皮病肾危象,其中4 例肾活检示小叶间动脉和入球小动脉内皮细胞增生、肿胀,内膜黏液性水肿,内弹力纤维断裂,"洋葱皮样"改变和肾小球弥漫性缺血;无恶性高血压表现2 例;急性肾小管坏死1 例。

The present study analysis whether CRP could directly induce inflammation in endothelial cells, analysis what kind of effects CRP provide on cellular signal transduction in endothelial cell by gene array, and isolate LDL by one step of density gradient centrifugation, generate E-LDL by degrading LDL with multiple enzymes, direct fluorescent labeling CRP and LDL, investigate whether CRP play as intermediator in atherosclerosis.

本课题目的在于探讨CRP在脂质参与的动脉粥样硬化形成中是否起到介质作用,主要通过检测直接CRP能否诱导内皮细胞炎症表现,基因芯片分析CRP对内皮系统的细胞信号转导通路的影响,探讨CRP参与调控内皮系统炎症过程的主要机制,并且通过一步法密度梯度离心分离LDL,复合酶处理生成E-LDL,直接荧光标记CRP和LDL,分析CRP介导脂质紊乱尤其是LDL代谢产物参与动脉粥样硬化早期形成的作用。

We observe the distribution, anastomosis relation of dorsal carpal branch of anterior interosseous artery.

一、通过50侧经动脉内灌注红色乳胶的成人尸体标本,对骨间前动脉腕背支走行、分支分布及其吻合关系进行观测

By pathology examination, the atherosclerotic plaques were found at the intima in Group I.

VEGF在动脉粥样硬化组织中蛋白及基因表达的研究应用免疫组化方法,观察动脉粥样硬化组织中VEGF蛋白表达的变化。

The results indicated that intramuscular endostatin gene delivery might be able to reduce the growth of the atherosclerotic plaques.

结果表明:内抑素基因转移能够抑制动脉粥样硬化斑块的生长,为动脉粥样硬化的治疗提供了新的思路和途径。

METHODS AND RESULTS: Adherent platelets express substantial amounts of SDF-1 and recruit CD34+ cells in vitro and in vivo. A monoclonal antibody to SDF-1 or to its counterreceptor, CXCR4, inhibits stem cell adhesion on adherent platelets under high arterial shear in vitro and after carotid ligation in mice, as determined by intravital fluorescence microscopy.

方法和结果:在体和离体的粘附血小板表达大量SDF-1、募集CD34+细胞,在体荧光镜下可见,在小鼠颈动脉结扎后、离体条件下的动脉内高剪切应力时,SDF-1或其相应受体的单克隆抗体-CXCR4抑制干细胞粘附于血小板上。

A monoclonal antibody to SDF-1 or to its counter receptor, CXCR4, inhibits stem cell adhesion on adherent platelets under high arterial shear in vitro and after carotid ligation in mice, as determined by intravital fluorescence microscopy.

采用活体荧光显微镜,对颈动脉结扎后小鼠和体外的高剪切力动脉进行研究,结果发现SDF-1的单克隆抗体或其反受体CXCR4,抑制干细胞黏附在相互黏附的血小板上。

Intubate into the arterial vessel of a frog and then mensurate the arterial blood pressure by using liquid-leading system.

在青蛙的左主动脉插入动脉插管,用液导系统直接测定其动脉血压。

Cevadine was isolated from Eranthis hyemalis and its effects on normal cats blood pressure, hypertension rats and their tolerance to cevadine were determined by using direct carotis and indirect arteria caudilis manometric methods.

从藜芦中提取分离出藜芦碱,采用颈动脉直接测压法和尾动脉间接测压法,测定了其对正常猫血压、高血压大鼠的影响及其快速耐受性。

Objective To introduce clinical experiences of the first dorsal metacarpal artery fascial flap with the different form.

目的介绍以第一掌背动脉为供血动脉的不同形式筋膜皮瓣的临床应用。

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