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The journal publishes original articles and clinical reports on scientific investigations and new developments in laboratory medicine in animals, including hematology, coagulation, immunology, clinical chemistry, endocrinology, cytopathology, surgical pathology, laboratory methods, quality assurance and instrumentation.

杂志刊载实验室动物医学的科学研究和新发展原始论文和临床报告,包括血液学,凝固作用,免疫学,临床化学,内分泌学,细胞病理学,外科病理学,实验方法,质量保证和仪器。

Oocytes of humans and animals often have long remained at meiotic diplotene.

人和动物的卵母细胞常长期停留在减数分裂的双线期。

RESULTSdiabetic rats showed typical symptoms involving elevated serum glucose and weight loss (2)The rats in DM+VaD group reacted slower and made more error numbers in Y-maze than the rats in VaD group did, with a prolonged total reacting time in a whole day.(3)More neurons with serious damages, such as edema, ischemia or pyknosis could be found in DM+VaD group than in VaD group. More disarrangement of cone neurons, obvious glia proliferation, and more neuron apoptosis were found in CA area of hippocampus. CONCLUSIONS (1)2-VO in STZ-induced diabetic rats succeeded in establishing VaD animal models.(2) The cognitive dysfunction induced by VaD rats had been deteriorated by diabetes mellitus.(3)Morphology evidences proved that diabetes mellitus aggravated brain damages induced by VaD.PART II Effect of diabetes mellitus on the cholinergic nervous systemin CA1 area of hippocampus of VaDOBJECTIVE To estimate the role of cholinergic nervous system in hippocampus during the process of cognitive dysfunction aggravated by diabetes mellitus in DM+VaD group. METHODS Observe the changes of ChAT protein by immunohistochemistry stain. Chose three rats randomly from each group at each pointat two week, four week, and eight week, then sepa

经腹腔注射链脲佐菌素诱导慢性实验性糖尿病,1周后永久性结扎双侧颈总动脉(2-VO)制作VaD模型记录术后2周、4周和8周各组大鼠的体重及血糖;应用Y-迷宫检测空间定向学第二军医大学博士论文中…丈摘…要1ia;一色恤~﹁染澎糕行HE染色观察组织病理学孪叱;胶质细胞原纤维酸性蛋白protellZ,Cf冰尸标记观察星形胶质细舱的激活情况、橄声软公点娜育票票众糯黑橄居端粗默孺篇筑价井袱第二部分糖尿病对血管性痴呆大鼠海马c心区胆碱能神经系统的影响探讨海马CAI区胆碱能神经系统在糖尿病加重确D一大鼠认知障碍中所实验动物及分组同第一部分,应用免疫组织化学染色方法现察海马CAI{介狱牛第晕军l袭拔常博粗{论义

In most cases, isolated genes or cells are duplicated for scientific study, and no new animal results.

在大多数情况下,孤立的基因或细胞复制的科学研究,并没有任何新的动物的结果。

Topics in mammalian learning and memory including cellular mechanisms of neural plasticity, electrophysiology, and behavior.

有关哺乳类动物学习和记忆的主题,包括神经可塑性的细胞机制、电生理和行为。

In many models of diabetes one has come to the conclusion that there is dysfunction of the endothelium.

从其他很多糖尿病动物模型实验中,都可以观察到内皮细胞功能障碍。

Toward this end, we evaluated small hairpin interfering RNAs targeting the conserved internal ribosome entry site element of the HCV genome for their ability to control gene expression in human cells and animals.

为此,我们评价了针对HCV基因组保守序列——内核糖体进入位点的小发卡RNA在人类细胞和动物体内控制基因表达的能力。

Histologic evaluation using hematoxylin and eosin stains confirmed the presence of cartilage nodules at 6 weeks after implantation.

软骨细胞以藻酸钙为载体在具有正常免疫功能的动物体内能形成特定形态的软骨组织。

Results: The concentrations of sIL-2R, IL-6 and ET in serum in asthma group were higher than that in control group (P.01), Manifestation of the lung tissue under electron microscope: the lung organism of the animal was infiltrated lamellarly by eosinophile granulocyte in the model set.

结果:模型组血浆中sIL-2R、IL-6和ET的含量与正常对照组比较明显增高(P.01),肺组织光镜和电镜下观察显示:模型组动物的肺组织可见嗜酸性粒细胞片状浸润,Ⅱ型细胞部分线粒体脊突消失、膨胀,板层小体减少,有较多排空现象。

The proximal and distal nerve stumps were sutured l cm apart, in an end-to-side fashion like "π", to the epneurium windows, opened by removing the epineural sheath on the intact tibial nerve trunk with 1 mm long.

方法将大鼠右侧腓总神经在胭窝处剪除约5mm后,将断裂的腓总神经近端和远端分别就近与同侧胫神经上的外膜窗施行端侧吻合,吻合口间距约10mm;动物存活24个月后,将手术侧近端吻合口以上胫神经剪断,再将辣根过氧化物酶注入远段腓总神经干内,72h后取材并经四甲基联苯胺显色显示脊髓L3-6节段神经元和L4、L5脊神经节细胞,同时取腓总神经远段行电镜观察神经纤维再生状态。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。