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So it is a effective prescription of protecting and treating AD.In our experiments, the model ras were administered D-gal intraperitioneal injection and β-Amyloid protein fragment_(1-40) into hippocampus. Mean well we used the technique of optical lens、 electron microscope、 immunohistochemical method, biochemistry and molecular biology.We studied the mechanisms that DR pretect and treat AD from the aspects of apoptosis、 inflammation injury、 oxidative injury 、 cholinergic neuron injury and the behavior experiments at cellar and molecular level.

本实验复制了D-gal腹腔注射合并Aβ_(1-40)海马定向注射AD动物模型,运用光、电镜技术及免疫组化、生物化学及分子生物学等先进检测方法,从行为学及细胞、分子水平探索地黄饮子对过氧化损伤、胆碱能损害、炎症损伤、细胞凋亡等相关调控因素影响的作用机制。

Objective: The purpose of our studies are gaining a better insight into the effect of genistein on mesangial cell"s phenotype change and ECM expression plus degradation under DN circumstances.We add genistein with different concentrations in high glucose cultured rat mesangial cells;feed DM rats with the single concentration genistein for different days;to explore the expression of SMemb,the mark of mesangial cell"s hypertrophy phenotype change;to examine the synthesis of Fn as well as the change of the balance between MMP-2 and TIMP-l;to comprehend its effect on renal pathological changes of DM rats and some related factors;trying toexplore the possible mechanisms.Through these studies,we will have some information about the experimental value of genistein in DN field.

目的:为了研究金雀异黄素对DN环境下大鼠MC肥大表型转换标志物SMemb和ECM分泌及降解的影响,我们拟在细胞水平以不同浓度的金雀异黄素作用于高糖培养下大鼠MC,在动物水平以同一浓度的金雀异黄素作用于DM大鼠不同时间,观察细胞表型转换标志物SMemb、ECM主要成分Fn、ECM降解酶系统基质金属蛋白酶—2(MMP-2)/基质金属蛋白酶抑制剂—1(TIMP-1)表达的变化,同时观察金雀异黄素对DM大鼠肾脏病理及影响肾脏病进展的糖脂代谢紊乱的影响,并进一步探讨金雀异黄素发挥作用的可能机制;为明确金雀异黄素在DN治疗中的地位及意义提供实验依据。

"Flame cell:a hollow cell in the excretory system of certain invertebrates , including flatworms and rotifers, containing a tuft of rapidly beating cilia that serve to propel waste products into excretory tubules."

"焰细胞:某种无脊椎动物在排泄系统中的空细胞,具有用来把废物推向排泄管的一簇能迅速摆动的纤毛。"

Methods Using Wistar rats as animal pattem of ADR-induced myocardial injury and sodium selenite as protective agent.The double flourescent staining of apoptosis and expression of transforming growth factor β1 (TGF β1) were examined in liver tissue of animal pattern of ADR-injury by immunohistochemical and TUNEL,and the level of lipid peroxidation in serum was observed.

通过复制大鼠阿霉素性心肌损伤的动物模型,以亚硒酸钠作为保护因素,应用原位末端标记法和免疫组化技术检测大鼠肝细胞凋亡和肝细胞转化生长因子β1表达,并观察了大鼠血清中脂质过氧化含量。

ACT is ready to try again with gaur and other endangered animals, Lanza says.

资助这项工程的位于马萨诸塞州Worcester的高级细胞技术公司的副总裁Robert Lanza说,若亚的死亡与克隆过程无关,高级细胞技术公司将继续用白肢野牛和其它的濒危动物作实验。

Calcium chloride modified nanoparticles prepared by means of chemistry. Analyse the combination of calcium phosphate nanoparticles and DNA, the protection to DNA as well by gelose gelatin electrophoresis. When the green fluorescence protein gene was regarded as report gene, gene vector of calcium phosphate nanoparticles transfected CNE-2 cell in vitro and vivo. Combine the calcium phosphate nanopartides and suicide gene yCDg1yTK for Nasopharyngeal Carcinoma therapy in vitro.

化学方法制备,氯化钙修饰纳米颗粒,用琼脂糖凝胶电泳分析磷酸钙纳米颗粒与DNA的结合效率及对DNA的保护作用,用绿色荧光蛋白基因作报告基因,将磷酸钙纳米颗粒为基因载体转染鼻咽癌(CNE-2)细胞和在动物体内转染肿瘤细胞;以及将磷酸钙纳米与自杀基因yCDglyTK结合,并在体外对鼻咽癌进行基因治疗。

The continuously growing incisor of the rodent is subdivided into a crown analog half on the labial side, with a cervical loop containing a large core of stellate reticulum, and its progeny gives rise to enamel producing.

啮齿类动物的切牙可以终生生长,它被分为了牙冠发育模式的唇侧和牙根发育模式的舌侧,唇侧的上皮包括一个颈环结构,其内含有星网状层细胞,可以不断的分化为成釉细胞并形成釉质。

Autotrransplant the cultured cell into the procine heart and set up atrioventricular block animal model to identify the cultured cell's function.

将培养细胞进行自体移植并建立房室传导阻滞动物模型以明确培养细胞的功能。

The journal publishes reports on clinical and experimental research in autoimmunity, as well as basic research, molecular, cellular and whole organism levels, in areas such as immunogenetics, immune cell signaling, molecular markers of autoimmune diseases, immune interventions, new animal models, transplantation, stem cell therapy, and gene therapy.

杂志刊载自身免疫的临床和实验性研究报告,以及基础研究,分子,细胞和整个有机体水平的研究,涉及领域包括免疫遗传学,免疫细胞信号,自身免疫性疾病的分子标记,免疫干涉,新动物模型,移植,干细胞治疗,和基因治疗。

Objective To evaluate the metabolic activity of adult xenogeneic animal hepatocytes to bilirubin after resuscitation from liquefacient nitrogen cryopreservation of patients with severe hepatitis.

目的 评价成年异种动物肝细胞液氮冻存復苏后对人重型肝炎胆红素的代谢活性,探討生物人工肝支持系统使用冻存復苏异种肝细胞的实际价值。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。