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动物细胞

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We further evaluated the synergistic cytotoxicity of TRAIL in combination with actinomycin D, cisplatin and paclitaxel in A549 cell lines in vitro and in vivo.

本实验选择了人肺腺癌A549细胞瘤株作为我们实验研究的对象,通过TRAIL对人肺腺癌A549细胞诱导凋亡研究,在A549的荷瘤裸鼠的动物模型上研究了其体内的抗肿瘤活性,并进一步研究了TRAIL与化疗药物放线菌素D(actinomycin D,Act D)、紫杉醇和顺铂(cisplatin,CDDP)的联合作用对人肺腺癌A549细胞的体外协同抗肿瘤活性,通过化疗药物协同增强TRAIL抗肿瘤活性作用机制的初步研究,为降低临床化疗药的用药量,减轻其对机体的不良反应提供一定的理论基础。

Objective: Augmenter of liver regeneration cloned from liver of weaning rat is a novel hepatic stimulator. It was reported that ALR mRNA expression was correlated with DNA synthesis of hepatocytes after partial hepatectomy, and could significantly promote the survial rate of intoxicated hepatitis rats.

目的:肝再生增强因子是从新生大鼠肝组织中克隆到的一种肝增殖刺激因子,其特异mRNA的表达与大鼠肝部分切除后肝细胞DNA合成密切相关,是一种特殊的促肝细胞分裂原,能特异地刺激肝细胞增殖,是肝再生的重要调控因子,能提高中毒性肝损伤动物的存活率,在肝损伤修复过程中发挥作用。

60Mm anterior and 1. 20mm lateral to bregma and 4. 00mm ventral to the cortical surface . 2 days later, ICH was induced by the standard method. At 7d, animals were sacrificed to investigate distribution of EGFP-expressing or BrdU-labeled cells around hemotoma.

根据以上实验结果,在分离、培养、传代获得NSC的基础上,采用pEGFP转染或BrdU标记体外培养NSC后,将细胞移植入前囟前1.60mm,矢状缝向右1.20mm,深4.00mm的细胞增生活跃的前脑脑室下区。2d后诱导脑出血模型,出血后7d处死动物检测EGFP或BrdU阳性细胞在血肿周围的分布情况。

In recent years,masenchymal stem cells have been applied in cartilage tissue engineering and they have shown significant potenital for carriage repair in animal models,and are being used as an ideal cell source in cartilage tissue engineering.

:间充质干细胞具有高度自我新能力,能够分化各类型的细胞近20年间充质细胞在软骨组织工程中得到应用,动物实验显示了良好的软骨修复潜能,成为软骨组织工程的理想的细胞来源。

The PKC family is subdivided into three groups; the classical PKC members are Ca〓 and diacylglycerol dependent, the novel PKCn are Ca〓-independent but diacylglycerol dependent and the atypical PKCs are not activated by Ca〓and diacylglycerol in vitro.

丝裂素活化蛋白激酶是一族在脊椎类动物体内广泛存在的蛋白质丝氨酸/苏氨酸激酶,是目前发现的最主要的一个生长信号调节蛋白,是细胞内多种促细胞增殖信息传递的共同通路或称会聚点,是细胞表型变化和增殖的蛋白激酶。

The SGC-7901GA cells and control cells SGC-7901Neo were cultured in vitro,and then were respectively injected into the endermic tissue of 6-weeks-old BALB/C node mice to create the animal models of tumor. The neoplasia and growth of tumor were observed. Use MTT method to detect the difference of growth capability of two kinds of cells in vitro.

先把SGC-7901~细胞和空白对照组细胞SGC-7901~进行体外培养,再把两种胃癌细胞接种于6周龄BALB/C裸鼠皮下,建立胃癌的裸鼠动物模型,观察裸鼠成瘤情况。

The results showed YYSXF could raise survival rate of the mice after irradition, increase activity of superoxide dismutose and reduce quantity of the lipid peroxide in liver and red blood cell, extenuate micronucleus formating in V79 4 cell, promote unscheduled DNA synthesis and induce production of interleukin 2 in spleen cells and protect bone marrow cells in mice.

结果表明养阴生血饮能提高致死剂量照射动物30d和小剂量多次照射60d及荷瘤小鼠1次照射后20d的存活率;能增加超氧化物岐化酶的活性;降低过氧化脂质的水平;减少细胞的微核形成;促进脾细胞DNA修复;诱导脾细胞产生白细胞介素-2;保护骨髓造血功能

The NK cytotoxicity was inhibited in RD-10 cells with high expression of MHC class Ⅰ molecules, but the γδT cells cytotoxicity was same among the three groups. Then the tumorgenicity of these tumor cells were determined in nude mice heterograft model in vivo.

动物接种肿瘤的实验结果表明,Balb/c裸鼠在接种野生型RD细胞、RD-neo细胞及RD-10细胞(低表达IL-15)后,各组小鼠肿瘤生长在体积和瘤重方面并无显著性差异。

In currence, se- GSH- PX activity have been been used as a standard of Selenium nourishment, GSH- PX is an extremely important protection enzyme in anti oxida- tive defend system of organize and cell of animal.It clear hydroxy radical and hyperoxide in cell respir- ation metabolism reaction ,thereby, mai- ntain cell's normal physiological function, prote- ct biomembrane and biomacromolecule from oxidative damage.If the activity is high or not, effect the ab- ility that the organize clears hyperoxize lipi- d ,directly.

目前,含se-GSH-PX活性已被作为se营养状况可一个指标,该酶是动物组织细胞抗氧化防御系统中一个极为重要的保护性酶,它是以还原型GSH为底物的谷胱甘肽参与的过氧化反应,清除细胞呼吸代谢反应过程产生的羟自由基和过氧化物,从而使细胞能维持正常的生理功能,保护生物膜和生物大分子结构免受氧化损伤。

Corals on both sides of a mouth trench mouth, comb jellyfish have tentacles on both sides of the body structure and the capsule show both sides of the symmetry, but other structural Jun Cheng radial arrangement.

多细胞动物的一种体制,兼有辐射对称和两侧对称的特点,见于栉水母动物及珊瑚纲动物。

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According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm~150rpm时取得最大值,此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世,形体几无变化。

When I was in school, the rabbi explained everythingin the Bible two different ways.

当我上学的时候,老师解释《圣经》用两种不同的方法。