动物实验的

PART ONEInvestigation on Hp CagA+ strain infection condition and pathogenesis risk analyze in patients of carotid atherosclerosisObjective To observate pathological changes of carotid atherosclerosis as well as Hp infection situation, examinate blood fats, blood serum hs-CRP, blood plasma YKL-40, blood serum sCD14, analyze relations between Hp or Hp CagA+ strain and carotid atherosclerosis, and explore possible mechanism of carotid atherosclerosis caused by infection.

然后进行基础动物实验，应用Hp CagA+菌株干预高脂血症大兔，建立Hp CagA+菌株感染致兔颈动脉粥样硬化模型，进行血清Hp抗体、hs-CRP、血浆YKL-40水平检测、斑块内Hp DNA，进一步求证Hp CagA+菌株感染和颈动脉粥样硬化形成的相关性，Hp CagA+菌株感染是否可促进颈动脉粥样硬化的形成，深入探讨其可能机制，以期为颈动脉粥样硬化形成的病因学研究提供实验基础，为临床治疗颈动脉粥样硬化提供新的策略，从而完善其防治模式。

A GFP-labeled Hela cell line and a mouse tumor model based on the cell line were established, and the animal model provides useful experimental materials for cervical cancer study. The in vivo fluorescence imaging system could be used to quantitatively evaluate the living tumor cell growth in vivo but not the size or volume of the tumor detected by slide caliper.

绿色荧光蛋白能够在人宫颈癌细胞Hela中长期稳定表达，用绿色荧光蛋白标记的人宫颈癌细胞Hela建立的裸鼠肿瘤模型可以为人宫颈癌研究提供理想的实验材料，应用小动物活体成像系统能够客观定量评价活的肿瘤细胞在动物体内的生长情况，而不是肿瘤体积的变化。

The tinnitus was induced by sodium salicylate injection. Results: The data of the experimen ts reported in this article suggests the presence of phantom auditory sensation in animals, produced by salicylate.

用注射水杨酸钠的方法造成动物耳鸣，通过不同组别大鼠行为实验的结果判断动物耳鸣的存在与否及男友药物的作用。

Objective To study the effect of different doses of wood frogegg oil on liver injury caused by CCl 4 .Methods In order to observe the effectof wood frog egg oil on weight,ALT,AST and TG in serum of animal,with wood frog egg oil soft capsule made up of extraction of wood frog egg in China and acute liver injury model caused by CCl 4 .The experiment on animal was done.

目的 探讨不同剂量的林蛙卵油对四氯化碳肝损伤的影响方法以中国林蛙卵提取物主要原料制成的林蛙卵油软胶囊，进行动物实验，利用CCl 4 作为肝脏毒物造成急性肝损伤模型，观察对动物体重、血清ALT、AST、TG的影响。

So,it is necessary and significant to study further and it will make a mirror in animal and anthropometric studies which would be carried out later.

发现脑脊液中各种离子的变化与缺血性脑损伤病理过程有重要的相关性，因此有进一步研究的必要性和重要意义，将为进一步开展动物实验和人体实验提供借鉴。

Objective:This project chooses the classic Chinese medicine prescription on treating ADHD——Kongsheng Zhenzhong Pill and studies it\'s impact on the signal trasmission of the neurotransmitter DA of the prefrontal cortex-basal ganglial circuit loop in the center of the ADHD animal model——SHR.The project tries to make clear Kongsheng Zhenzhong pill\'s curative effect in animal experiment and explore in depth the mechanism of treating ADHD with Chinese medicine.

一、研究目的本课题选择中医药治疗ADHD的代表方剂——孔圣枕中丹，研究其对ADHD动物模型自发性高血压大鼠中枢前额叶皮质—基底神经节环路的神经递质DA的信号传导的影响，明确孔圣枕中丹在动物实验中的疗效，深入探索中医药治疗ADHD的具体机制。

The aim of present study is to examine the influence of Adriamycin retrogradely transported via the axon on neuropeptide expression within the spinal trigeminal nucleus through animal experiment to explore the relation- ship between neuropeptide and pathogenesis of trigeminal neuralgia.

本实验的目的是通过动物实验来探索阿霉素通过轴浆逆行传递对三叉神经脊束核内神经肽表达的影响，探寻神经肽与三叉神经痛的发病关系。

The donor liver was cold perfused through abdominal aorta and portal vein respectively, the liver of recipient was step-excised, the suprahepatic vena cavewas sutured end -to -end with 8-0 nylon line, and the continuity of infrahepatic VC and portal veinwere established by means of cuff method respectively.

作者在参考Kamada等[1，2]用&二袖套法&吻合血管的基础上，并对供肝的灌注、受体肝脏切除及移植肝脏的血流重建等进行改进，以提供一个稳定可靠的动物模型的建立方法。1材料与方法1.1实验动物、药品及术前准备采用健康、成年、雄性、清洁级体重约200￣300g SD大鼠和二级Wistar大鼠，饲养条件符合SPF标准由南方医科大学南方医院实

In the experimental study section, the rats were divided into four groups, including the normal control, the model, the Piracetam, the QPC, and copied to AD model. After the treatment, we observed the effects on the AD rats' ability of leaning and memorizing, detecting the TChE activity in whole blood and the expression levels of the related biochemical indicators of As includeing GFAP、NGF and BDNF of the AD rats' brain hippocampus, then compared the QPC with other groups to reveal the mechanism of action of the QPC treating AD to bright.

在动物实验部分，我们通过塑造AD动物模型，设立正常对照组、模型组、脑复康组和强脾益智胶囊组，观察强脾益智胶囊对AD模型大鼠空间学习记忆能力的影响，检测AD大鼠全血、海马匀浆液中乙酰胆碱酯酶活性和通过免疫组化的方法检测胶质纤维酸性蛋白、神经生长因子、和脑源性神经营养因子的表达情况来反映星形胶质细胞的增值情况，以期揭示强脾益智胶囊对AD的治疗作用机理。

PC-DCP, which consisted of two parts, Dynamic Compression Plate and Point Contact Nut, use bi-cortical screws to fix fractures.Fracture stability was enhanced through PC NUT conical tips piercing intocortical bone beneath the plate.

本研究以传统DCP为对照，通过对PC-DCP的生物力学性能、生物学性能及动物实验应用几个方面的研究，从而为将来的临床应用提供理论和实验依据。

This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。