动物化学的

Methodssmear 0.25% croton oil＼acetone ag on the back of kunming mice,and observe the growth condition of papilloma,then record the quantity of tumor-bearing mice and the quantity of tumor in each mice.results20-ginsenoside rh2 prolonged the incubation of tumor, reduced the quantity of tumor-bearing mice and decreased the amount of tumor in each mice.conclusion20ginsenoside rh2 has obvious anti-papilloma effect on the mice skin.

结果20-人参皂苷rh2对小鼠皮肤乳头状瘤有明显的抑制作用，可使肿瘤发生潜伏期延长，使化学致癌物诱发的荷瘤动物数明显减少，每鼠荷瘤数显著下降。结论20r 人参皂苷rh2在预防癌症的发生和发展方面有重要的作用，也是很有前景的新型抗癌药。

Barrington's nucleus that located in the pontine dorsolateral tegmentum is an important site for controlling voiding in the mammalian brain and is often referred to as pontine micturition center. Barrington's nucleus sends direct projection fibers to the sacral parasympathetic nucleus in which parasympathetic preganglionic neurons innervating detrusor muscles of the bladder are distributed. Electron or chemical stimulation of Barrington's nucleus clicits bladder contraction and increases discharges of bladder postganglionic nerve. Conversely, lesion of the nucleus results in a permanent inability to empty the bladder. On the other hand, an area located just ventral to Barrington's nucleu has been reported to send projection fibers to the ventrolateral group of Onuf's nucleus in the caudal lumbar cord segments; the vetrolateral group of Onuf's nucleus is mainly composed of pudendal motor neurons innervating the external urethral sphincter muscle.

Barrington's核发出纤维投射至支配膀胱逼尿肌的骶髓副交感核，毁损该区可导致动物永久性失去排空膀胱的能力；而电刺激或化学刺激该区可引起支配膀胱的节后纤维放电增加和膀胱逼尿肌收缩。D区是紧邻Barrington's核腹侧的一团神经元，它发出纤维投射至腰骶髓Ounf核的腹外侧群，而Ounf核的腹外侧群主要是由支配尿道外括约肌的阴部神经运动神经元组成。

For the first time in the world, an in vitro testing model based on FRTL-5 cell line for thyroglobulin disruptors was established, as well as an in vivo testing model acting as a compensation for the in vitro method. The feasibility of the combination of in vitro and in vivo screening methods was discussed, as well as the mechanism of thyroid hormone disruptors.

为达到这一目的，我们在国内外率先建立了FRTL-5细胞对干扰甲状腺球蛋白的化学物的体外甄别方法模型，并建立相应的体内动物实验模型以弥补体外甄别方法在特异性上的不足，探讨以此建立体外、体内试验相结合的甄别方法体系的可行性，同时初步探讨甲状腺素干扰物的作用机制。

In this research, the pubertal five-week-old SD rats were chose as experimental object to establish the animal model for simulating maxillary protraction, on which was imposed the orthopedic force of 85g with utilizing the self-devised maxillary protraction appliance. Located lateral X-ray cephalograms were taken to measure and analyze the changes of maxillary development after exerting the orthopedic force for 4 weeks. The technique of immunohistochemistry was used to investigate theexpression of TGF-, in frontomaxillary sutures and palatomaxillary sutures with identical force performing for different extent of time. The average hue was selected as indicator, which was measured by the means of the analysis system of pathological color images. The measuring data were analyzed by the one-way ANOVA in software SPSS 11.0 version.

本研究采用自行设计的上颌前牵引装置，以生长发育期5周龄SD大鼠为实验对象，施加85g的矫形力，建立了模拟上颌前牵引的动物模型，通过X线头影测量分析，观察施力4周后上颌骨的生长发育情况；应用免疫组织化学技术，检测同一力值作用不同时段下TGF-β_1在上颌骨的额颌缝、腭颌缝的表达，彩色病理图象分析系统测定每张切片中阳性染色细胞的平均灰度值，结果采用SPSS 11.0进行方差分析。

Investigation of major metabolic pathways of SFZ-47 in animals The metabolites of SFZ-47 in rabbit urine following oral administration were separated and detected with HPLC and LC-MS methods. On the basis of the chromatographic behavior and mass spectra of the metabolites as well as biotransformation pathways of drugs with the partial structure of SFZ-47, the hydroxylic derivative 4-(3H-1, 2- dihydro-1-pyrrolizinone-2-methylamino benzyl alcohol and the carboxylic derivative 4-(3H-1, 2-dihydro-1-pyrrolizinone-2-methylamino benzoic acid of SFZ-47 were proposed as two potential metabolites and were synthesized.

在动物体内主要代谢途径的确定用HPLC和LC-MS对家兔口服SFZ-47后尿中的代谢物进行了分离、检测，根据代谢产物的色谱和质谱行为以及与SFZ-47有类似结构部分的其它药物的代谢途径，推测其羟基衍生物[4-（3H-1，2-二氢-1-吡咯里嗪酮-2-甲基胺基）苯甲醇]与羧基衍生物[4-（3H-1，2-二氢-1-吡咯里嗪酮-2-甲基胺基）苯甲酸]是两种可能的代谢产物，遂用化学方法合成了这两种衍生物。

These results also provedthe presence of the same acute phase response profile in amphioxus,as observed ineutherians.Thus it pushed the evolutionary existence of the eutherian-like acute phaseresponse back to the protochordate lineage.Fourthly,we determined CAs,including epinephrine、norepinephrin anddopamine,with HPLC method optimized after LPS challenged amphioxus.Theresults demonstrated that E,DE and DA are present in amphioxus humoral fluid,andE was firstly found in amphioxus.

第三，我们用生物化学方法，选取海洋中广泛存在、众多水产动物的常见致病菌-溶藻弧菌作为天然反应原感染文昌鱼，从另外一个角度探讨并丰富文昌鱼体液中的八种炎性蛋白的急性时相反应，结果显示，与LPS感染文昌鱼相比，六种正APPs的浓度变化幅度相对较小，曲线相对平缓，但仍然呈正急性时相反应，蛋白电泳也证实了这一点；而二种负APPs：RBP和白蛋白(Albumin，ALB)浓度实验周期内总体呈下降的趋势，呈负急性时相反应，结论与上述LPS相同。

Simultaneous determination of N, N-Dimethylaniline and phenol in wastewater by high-performance liquid chromatography with chemiluminescence detection; 2 rapid determination of rudimental trace aniline in indigotine by reverse phase HPLC; 3 determination of the levels of tetracycline and oxytetracycline residues in liver tissue by HPLC-CL; 4 rapid determination of Shikimic acid in taxodium distichum by ion-suppression reversed-phase HPLC.

第二节是高效液相色谱及其与化学发光柱后检测技术在药物分析中的应用，研究了四环素、土霉素的HPLC-CL方法，应用于动物肝组织中四环素、土霉素残留量的测定；并研究了用离子抑制-反相高效液相色谱法快速测定落羽杉中的莽草酸的新方法。

Camping in style: The new Mandare River Camp is the first African-style luxury tented camp to open in Madagascar. Six tented rooms have biodegradable chemi-loos, solar-powered electricity and private verandahs - perfect for wildlife watching

野营风尚：这新推出的 Mandare 河露营是第一个非洲风格的奢华帐篷露营，他将在马达拉斯加拉开帷幕。6个帐篷型的房子内配备了可生物降解的化学厕所，太阳能供电系统和非常适合观察野生动物的私人阳台。

Caption:Camping in style: The new Mandare River Camp is the first African-style luxury tented camp to open in Madagascar. Six tented rooms have biodegradable chemi-loos, solar-powered electricity and private verandahs - perfect for wildlife watching

描述：露营新趋势：新马尼达河营是在马达加斯加开的第一个的非洲风格的豪华帐篷形露营。6个帐篷形的房间有着可以生物降解的化学洗手间，太阳能电源和私人走廊——完美的野生动物观赏地。

The results of this experiment were different from previous study which suggests that the study on plant chemical defense in large geography scale is difficult and the results may be affected by the background of seedlings and experimental animals and the measured features. So that, more experiments should be carried on in the future.

本文的试验结果与过去的相关研究结果有一定差异，说明大地理范围的植物化学防护研究并不简单，其结果可能受种前的遗传背景、实验动物背景、所选的观测指标等诸多因素影响，因此需要进一步的反复实验。

As she looked at Warrington's manly face, and dark, melancholy eyes, she had settled in her mind that he must have been the victim of an unhappy attachment.

每逢看到沃林顿那刚毅的脸，那乌黑、忧郁的眼睛，她便会相信，他一定作过不幸的爱情的受害者。

Maybe they'll disappear into a pothole.

也许他们将在壶穴里消失