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MethodsEarly embryos at different stages and uterus of the non-pregnant, and pregnant uterus of 1 to 8 days pseudopregnancy in mice were obtained.

方法取小鼠早期胚胎、动情期未孕、真孕及假孕1~8d小鼠子宫,利用免疫组织化学染色及图像分析法,检测p38MAPK在不同发育阶段早胚及围植入期子宫内膜中的表达和变化规律。

Methods: Tissue of rat ovary was obtained from 30 healthy sexually mature non-mated femal SD rats. The rats were divided into two groups (oestrus group and anoestrus group). The expression of α-SMA and vimentin were detected and evaluated by immunohistochemistry and image analysis system in the theca cells of different type follicles.

分别取动情期和非动情期大鼠卵巢,运用免疫组化方法检测肌成纤维细胞的特征性标记和波形蛋白分别在这两组中各级卵泡卵泡膜细胞上的表达情况,并进行图像分析。

Of animals that have several estrous cycles in one breeding season in a period of sexual inactivity.

指在一个繁殖期有几个发情周期的动物)不动情期

The level of UEA receptor at diestrus was much higher than that at estrus and that of pregnancy.

动情间期UEA受体水平明显高于动情期和孕期(P<0.01)。

ECL and PHAL receptors maintained a lower level at day 4 and 5 of pregnancy than those at the diestrus.

d的水平显著低于动情间期和动情期(P<0.01)。

The level of the UEA receptor at diestrus was much higher than that at estrus and that of pregnancy.

动情间期UEA受体水平明显高于动情期和孕期(P<0.01)。

The level of the ECL and the PHAL receptors were higher at the estrus than at diestrus.

ECL和PHAL受体水平在动情期高于动情间期,孕期呈现先下降后上升的趋势,且在孕4、孕5?

During periimplantation, the decrease of the ECL and the PHAL receptors may lead to the failure of implantation in the oviduct, and the increase of the UEA receptors at diestrus may contribute to the process of fertilization.

围植入期ECL和PHAL受体表达下降,在输卵管内形成了不利于植入的微环境,可能是胚泡正常情况下不植入输卵管的原因之一;动情期UEA受体水平显著低于动情间期,有利于受精过程的正常进行。

According to the WHOQOI-100 and WHOQOL-BREF measuring scale about quality of life , the state of quality of life were observed in these two groups; The visual vague scale was adopted to survey the degree to improve the dysmenorrhea.3 Animal Experiment 60 healthy sanitation female Wistar rat with normal estrous cycle were selected,200±20g in weight,according to the result of vaginal smear examination, make the model with operation at estrum to duplicate the model of endometriosis according to the Wang Yan-ping's method, the abdomen of the sham operated group were opened and closed with no management.

参考WHOQOI-100和WHOQOL-BREF生存质量测定量表,观察两组患者的生活质量;采用视觉模糊评分法观察患者的痛经改善程度。3动物实验选用动情周期正常的健康清洁级雌性成年Wistar大鼠60只,体重200±20g克,经阴道涂片检查,在大鼠的动情期进行手术造模。

The higher level of E2 and P in estrus and metestrus have inhibitory effect on TNFα production.

动情期和动情后期由于较高水平的E2和P含量对LPS诱导的TNFαmRNA表达和TNFα含量的升高有抑制作用。

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