加重

It is usually light in the walk and halt, stronger in the trot and canter.

通常在慢步和停止的时候指令轻微，在快步和跑步时加重。

But by the time the company actually made its first million, the careerism and money seemed only to embolden their blindness.

但是当公司挣了第一个一百万时，利欲熏心与金钱看上去仅仅加重了他们的盲目愚昧。

The content of TGF β in serum of COPD acute exacerbation was higher than that in normal control group and COPD catabasis group, but compared COPD catabasis and normal control group, no significant difference was found.

COPD急性加重期血清TGF β浓度高于缓解期及正常对照组，有显著性差异，但缓解期与正常对照组相比较无显著性差异。

Consider to discover, OSAHS patient appears because of relapsing in nightly Morpheus disease of blood of low oxygen, tall carbonic acid, consensual as disorder as parasympathetic nerve function, already made coronary heart disease (the cardiovascular disease such as CHD) sparks importantly element, can cause all sorts of rhythm of the heart wrong, aggravating cardiac muscle is short of blood, produce sudden death of heart source sex even. 1 O SAH S and hypertensive disease consider to discover, OSAHS patient's nightly small arousal can bring about sympathetic stimulant increase, adrenalin can nerve medium if adrenalin, go adrenalin secretes armour grow in quantity, heighten of material of phenolic amine of catechu of nightly make water.

探究发现，OSAHS患者夜间睡眠中因反复出现低氧、高碳酸血症、交感和副交感神经功能紊乱，已成为冠心病等心血管疾病重要的触发因素，可诱发各种心律失常、加重心肌缺血，甚至发生心源性猝死。1 O SAH S和高血压病探究发现，OSAHS患者夜间的微觉醒可导致交感神经兴奋性增强，肾上腺素能神经介质如肾上腺素、去甲肾上腺素分泌增多，夜间尿儿茶酚胺类物质增高。

The blood pressure of.1 of pathology physiology mechanism that SAS causes CVD breathes time-out to be able to bring about airframe in elevatory Morpheus anoxic, sympathetic is excessive and excited, element of serous catechu phenolic amine, kidney and hemal endodermis element are elevatory, bring about hemal easy of hemal convulsion; to shrink the function is disorder, can make blood-vessel flowing flesh happening reframes and fleshy, systemic blood-vessel obstruction adds element of the kidney when; is chronic and anoxic, system of hemal and nervous element is activationed, bring about blood pressure to lift. Obstruction of way of energy of life of patient of OSAS of disease of blood of 1.2 low oxygen increases, cause air current to interrupt, breath pauses, at the same time airframe gets used to low oxygen environment gradually, breathing centre drops to low oxygen and sensitivity of disease of blood of tall carbonic acid, breath suspends a frequency increasing, farther aggravating airframe is anoxic. 1.3 heads are self-adjusting the function drops normal person changes quickly in systematic circulation blood pressure when, the head can be passed adjust independently functional generation protects effect, make change of cerebral blood flow not big.

SAS诱发CVD的病理生理机制。1血压升高睡眠中呼吸暂停可导致机体缺氧，交感神经过度兴奋，血浆儿茶酚胺、肾素以及血管内皮素升高，导致血管痉挛；血管舒缩功能紊乱，可使血管平滑肌发生重构和肥厚，全身血管阻力增加；慢性缺氧时肾素—血管紧张素系统被激活，导致血压升高。1.2低氧血症OSAS患者气道阻力增加，造成气流中断、呼吸暂停，同时机体逐渐适应低氧环境，呼吸中枢对低氧和高碳酸血症敏感性下降，呼吸暂停次数增加，进一步加重机体缺氧。1.3脑自动调节功能下降正常人在体循环血压快速变化时，脑可通过自主调节功能产生保护效应，使脑血流量变化不大。

A theoretical understanding of the dynamics of flight was first defined in print by Sir George Cayley in 1809, the same year he built and flew a heavier-than-air model.

一个理论的认识，动态飞行首次界定的打印由主席先生乔治的Cayley在1809年，同年他建立了飞往加重了比空气模型。

A centaur is as big as a heavy horse, but much taller and slightly heavier.

一个半人马如同一只笨重的马一般大，但身高和略有加重。

As reported in the medical journal Cephalalgia, the subjects said they felt an increase in pain or discomfort during 68 per cent of all trials.

在医学杂志Cephalalgia上发表的研究报告表明，在68%的试验中，研究对象称感到头痛或不适症状加重。

I will also go against you with opposite fury, and I will chastise you with seven plagues for your sins

我必发怒来与你们作对，为了你们的罪恶，我必加重七倍惩罚你们。

If even after this you do not obey me, I will increase the chastisement for your sins sevenfold

如果这样你们还不听从我，为了你们的罪恶，我必要加重七倍惩罚你们

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。