加酶的

Bronchial asthma is the most common chronic diseases in children.Asthma can not be fully explained by imbalance of Thl/Th2.With the research progress of CD4+ CD25+ Treg cell,it has been found that CD4+ CD25+ Treg cell related factors such as forkhead/winged helix transcription factor,heine oxygenase-1,transforming growth factor-β,cytotoxic T lymphocyte-associated antigen-4 are closely linked to asthmatic mechanisms.

支气管哮喘是一种儿童时期最常见的慢性疾病，单纯的Thl/Th2应答失衡并不能完全解释支气管哮喘的发生，伴随着CD4+CD25+调节性T细胞的研究进展，人们发现与CD4+CD25+Treg细胞相关的因素如叉头/翼状螺旋转录因子、血红蛋白加氧酶-1、转化生长因子β、细胞毒性T淋巴细胞相关抗原-4与支气管哮喘均有密切的联系。

The article studied on processing technology of tomato beverage using tomato as material, they did experiment aim to increase juice yield , stability of the beverge and to keep colour. The results indicated juice yield is able to reach 81.5% after preheating, adding pectase , pressure filtering, the processing technology improved the utilization of tomato.

以番茄为原料进行饮料的加工，针对提高番茄出汁率、饮料稳定性、饮料色泽的保持工艺研究实验，结果发现，对番茄预热后，再加果胶酶处理、加压过滤工艺可使番茄的出汁率达到81.5%，提高了番茄的利用率；番茄饮料中添加2‰，质量比5：2：3的羧甲基纤维素钠、黄原胶、琼脂复配增稠剂可使饮料在常温保存三个月仍具有良好的稳定性。

During these years (1997-2000) in the research area of annonaceous acetogenins 5 natural products and a number of chiral-pure analogs of annonaceous acetogenins have been synthesized using sugars as the starting materials. Their high activity and selectivity against cell line of colon tumor and a relationship between activity and configuration have been found too. In the respect of inhibitor of sialidase two new methodologies for the synthesis of chiral-pure 3-deoxy-ulosonic acid using hetero-Diels-Alder reaction or asymmetric propargylation as the key reaction were developed. On the topic of anti-leukemia marine natural product clavulactone a synthetic method based on the free radical cyclization and starting from sugar has been developed. In other title of PKC inhibited agent sphingosine a new synthetic route with SN2' as the key reaction has also been disclosed.

项目期间（1997-2000）在番荔枝内酯方面从糖出发合成了五个天然产物和一批手性纯的类似物，它们对肠癌细胞有很高的活性和选择性，并与构型有关；在唾液酸酶抑制剂方面发展了二类全新手性纯高碳糖的合成方法－杂原子D－A反应或丙炔基不对称加成为关键的反应；抗白血病海洋天然产物群柱虫内酯方面研究了由糖出发和自由基环化反应的合成方法；对PKC 起抑制作用的鞘氨醇方面也开创了新的合成途径－由糖出发并以SN2'反应为关键反应。

According to the alignment of Blastn and Blastx, one differentially exp ressed fragment, A7, was 97% identical in nucleotides to the 26S ribosomal RNA gene of Photinia fraseri and 91% in amino acids to cytochrome P450 monooxygenase in maize, respectively. Another differentially exp ressed fragment, A16, was 85% in nucleotides and 93% in amino acids identical to alpha-expansin 2 in Triphysaria versicolor.

核酸和氨基酸比对分析中同源性最高的是片段A7和A16.A7的核苷酸序列同源于红叶石楠Photinia fraseri 26S核糖体RNA (97%)、蛋白同源于玉米的细胞色素P450单加氧酶(91%)， A16的核苷酸(85%)及蛋白(93%)同源于直果草属 Triphysaria versicolor 的α-expansin 2基因。

The invention uses low cost grease which are mainly waste resources such as the unedible Jatropha curcas seed oil, the waster oil in the restaurant industry and the acid value oil, etc. as raw materials, thereby enlarging the material sources; because the Rhizopus chinensis CCTCC M201021 full cell lipase which is extremely low in cost is used as the catalyst, the problem of high price catalyst is effectively resolved; the toxic action of the alcohol on the biological catalyst is resolved by the batching fed-batch the short chain alcohol, thereby improving the conversion rate of the short chain alcohol.

本发明以廉价油脂为原料，主要是非可食用性的麻疯籽油以及餐饮业废油、酸价油等废物资源，扩大了原料的来源；采用价格极其低廉的华根霉全细胞脂肪酶作为催化剂，有效地解决了催化剂价格高昂的问题；分批流加短链醇以解决醇对生物催化剂的毒害作用，提高短链醇转化率。

Simultaneously we prepared benzimidazolines with two methods by the of reduction benzimidazolium salts with NaBH_4 and Grignard addition with benzimidazolium salts. Thus we provided a new biomimic synthetic method for 13 kind of tetrahydroisoquinoline starting from carboxylic aicd and halid, gave a new idea of the synthesis for new drugs.It can make many kind ofβ-carboline alkaloids which have bioactivity to antibacterium, antivirus and antitumor to start from 1,2,3,4-tetrahydro -β-carboline.

本文以1，3-二甲基苯并咪唑碘盐和2-取代的1，3-二甲基苯并咪唑碘盐为原料，采用了NaBH_4还原和Grignard试剂加成两种方法，制备了13种1，3-二甲基苯并咪唑烷和2-取代的1，3-二甲基苯并咪唑烷作为四氢叶酸辅酶一碳单元转移新模型，在酸性条件下，以2-(3，4-二甲氧基苯基)乙胺作为接收一碳转移的亲核试剂，完成了13种重要的四氢异喹啉类化合物的新合成方法研究。

Therefore these regions of HBV genome are attractive targets for antiviral therapy mediated by ribozymes.

因此，HBV的加尾信号部位和HBV中C基因的3'端保守区是核酶介导的抗病毒研究的理想的靶位点。

According to the clear water experiment, aeration performance of the new equipment is good with high total oxygen transfer coefficient and oxygen utilization ratio.

曝气设备的动力效率在叶轮转速为120rpm～150rpm时取得最大值，此时氧利用率和充氧能力也具有较高值。

The environmental stability of that world - including its crushing pressures and icy darkness - means that some of its most famous inhabitants have survived for eons as evolutionary throwbacks, their bodies undergoing little change.

稳定的海底环境─包括能把人压扁的压力和冰冷的黑暗─意谓海底某些最知名的栖居生物已以演化返祖的样态活了万世，形体几无变化。