加氨的

Based on the addition of vinyl magnesium bromide to the chiral non-racemic synthon 2 derived from-1, an enantioselective total synthesis of-3, the antipode of marine alkaloid halitulin 10 steps, overall yield: 5.3% from (R-1 was achieved using aza-Claisen rearrangement as a key step.

取得的主要结果如下：一、从-苯基甘氨醇1出发，通过已知的哌啶手性合成砌块2的加成反应，建立了经aza-Claisen重排反应进行海洋生物碱halitulin手性分子片断的对映体--isohaliclorensin 3不对称合成的路线。

Based on the addition of vinyl magnesium bromide to the chiral non-racemic synthon 2 derived from-1, an enantioselective total synthesis of-3, the antipode of marine alkaloid halitulin 10 steps, overall yield: 5.3% from (R-1 was achieved using aza-Claisen...

取得的主要结果如下：一、从-苯基甘氨醇1出发，通过已知的哌啶手性合成砌块2的加成反应，建立了经aza-Claisen重排反应进行海洋生物碱halitulin手性分子片断的对映体--isohaliclorensin 3不对称合成的路线。

Synthesis of novel sulfonamide-prolinols and their application on the asymmetric addition of diethylzinc to benzaldehyde.

三、研究了脯氨酸衍生的新型手性磺酰胺-氨基醇的合成及其催化二乙基锌对苯甲醛的不对称加成反应 1。

Four new chiral sulfonamide alcohol s were synthesized from camphor and L-phenylalanine and their application to the enantioselective addition of diethylzinc to benzaldehyde was described.

由天然樟脑和-苯丙氨酸合成了4个新的手性磺酰胺醇，并对其在二乙基锌对苯甲醛的不对称加成中的催化性能进行了研究。

Four new chiral sulfonamide alcohols were synthesized from camphor and L-phenylalanine and their application to the enantioselective addition of diethylzinc to benzaldehyde was described.

由天然樟脑和-苯丙氨酸合成了4个新的手性磺酰胺醇，并对其在二乙基锌对苯甲醛的不对称加成中的催化性能进行了研究。

Better denitrification efficiency could be obtained with adding amylo and the removal ratios of ammonia nitrogen were at least 93%. The removal ratio of TN increased gradually with the increasing of C/N ratio. When C/N ratio was 10, the best removal ratio of TN could reach 80.81%. But when C/N ratio added on 12, the ratio removal of TN was not increased only keeping about 75%.

投加淀粉调整C/N比，系统能取得良好的脱氮效果，氨氮的去除率均在93%以上，随着C/N比的增加，TN的去除率也逐渐的增大，当C/N为10时，TN最高去除率能达到80.81%，但当C/N增大到12时，TN的去除率不再增大，只是稳定在75%左右。

A compound 2-(3-hydroxyphenyl)[60] fullerene pyrrolidine was synthesized by the 1,3-dipolar cycloaddition reaction of the fullerene(C60) and azomethine ylide (prepared from glycine and 3-hydroxybenzaldehyde). The product was characterized by UV-Vis,1H-NMR ,FT-IR and MS. The reaction conditions affecting the yields of product were investigated and the optimum reaction conditions with product yield 75%(based on consumed C60) were:molar ratio of C60∶3-hydroxybenzaldehyde:glycine 1∶3∶6,reaction temperature 95℃,reaction time 18h.

利用甘氨酸和3-羟基苯甲醛与C60发生1， 3-偶极环加成反应，合成分离得到了2-(3-羟基苯基)[60]富勒烯吡咯烷，用UV-Vis、1H-NMR、FT-IR、MS等测试手段表征了产物的结构，并通过单因素方法，探讨了反应条件对产物产率的影响，得到最佳工艺条件：反应物摩尔比1∶3∶6，温度95 ℃，反应时间18 h，产物的产率可达75%（以消耗的C60计）。

The optimum process starting from 1,3-dihydroxyacetone and formamidine acetate was: 22.54g(0.25mol) 1,3-dihydroxyacetone, 29.12g(0.28mol) formamidine acetate and 120ml isopropanol in liquid ammonia was heated to 40℃ for 8h.

以1，3-二羟基丙酮和醋酸甲脒为原料的较佳工艺：1，3-二羟基丙酮22.54g (0.25mol)，醋酸甲脒29.12g (0.28mol)，异丙醇120ml，通入液氨，40℃反应8h，减压蒸馏除去反应液中的氨气后过滤，滤液加至热的苦味酸饱和溶液，自然冷却至室温，制得4(5)-羟甲基咪唑苦味酸盐69.5g，收率85.0%。

(1)PAL is better entrapped by PAG with a T∶C ratio of 8∶30.(2)PAL immobilized by glutaric dialdehyde on Bio-Gel P-300 is better than by CDC.(3)The best one is the dehydration and redehydration method.(4)Immobilized and permeated PAL active yeast cells are resistant to trypsin digestion and retain its PAL activity.

(1)固定化酶活性采用T∶C比为8∶30明显高于8∶19；(2)以戊二醛将PAL固定于Bio-GelP300优于用DCD固定化的酶；(3)质脂体包被中以脱水再加水法对酶活性影响较少，脂类组成以磷脂酰胆碱：胆固醇：磷脂酰丝氨酸比值7∶2∶1最好；(4)固定化PAL活性酵母细胞能较好地抵抗人工肠液中胰蛋白酶的水解作用，亦能明显降低苯丙氨酸的浓度。

Three part of research works had been carried out in the dissertation. The first part: a kind of multidentate amine modified silica gel was synthesized through the following steps:(1) introduce the amino groups onto the surface of silica-gel by the treatment of surface silanol groups withγ-aminopropyl trimethoxy silane;(2) michael addition of excess trihydroxymethyl propyl triacrylate to amino groups on the silica gel surface;(3) amidation of the unreacted double bonds of TMPTA on the surface of TMPTA modified silica gel with diethylenetriamine;(4) the multidentate amine modified silica gel was finally obtained by the reaction of amino groups on the surface of DETA modified silica gel with double bond of butyl acrylate.

本论文进行了三部分研究工作，第一部分：通过多步反应对硅胶进行改性合成了一种多齿胺改性硅胶配体，合成过程如下：1通过γ-氨丙基三甲氧基硅烷与硅胶表面的硅羟基反应，使硅胶表面带有氨基；2利用硅胶表面氨基与过量的三羟甲基丙烷三丙烯酸酯发生Michael加成反应；3利用二乙烯三胺与TMPTA改性硅胶表面未反应的双键发生反应使硅胶表面氨基化；4最后用丙烯酸正丁酯与DETA改性硅胶表面氨基充分反应成功合多齿胺改性硅胶配体。

I didn't watch TV last night, because it .

昨晚我没有看电视，因为电视机坏了。

Since this year, in a lot of villages of Beijing, TV of elevator liquid crystal was removed.

今年以来，在北京的很多小区里，电梯液晶电视被撤了下来。