加合化合物

In the ESI+ mode the compound isolated from fraction III/9 showed a pseudo-molecular ion of m/z 261 ([M + 1]+) as well as sodium and potassium adducts with m/z 283 and m/z 299, respectively, thus suggesting a molecular mass of 260 Da.

在 ESI+模式下，从子馏分 III/9中提取出来的化合物分别出现了伪分子离子 m/z 261 ([M + 1]+)和纳钾加合物 m/z 283 and m/z 299，这样就暗示了260 Da 的分子质量。

Methods In view of the selective accumulation of porphyrin derivatives in tumor tissue, three ftorafur-porphyrin compounds and three metal compounds were designed, and the target compounds were synthesized with satisfied yield via a four-step procedure starting from pyrrol and substituted benzaldehydes.

根据卟啉对肿瘤组织的选择性滞留作用，设计了3个卟啉替加氟化合物及3个金属络合物，并以吡咯和取代苯甲醛为原料经4步反应以满意的收率得到目标化合物。

Master the Keto-Enol tautomerism; reactions of enols:α-H substitution reactions;α-halogenation of aldehydes and ketones;α-bromination of carboxylic acids; acidity ofα-H atoms: enolate ion formation; reactivity of enolate ions; alkylation of enolate ions; mechanism of carbonyl condensation reactions;condensations of aldehydes and ketones: the Aldol reaction; dehydration of Aldol products; the Claisen condensation reaction; the Michael addition.

熟练掌握酮式－烯醇式互变异构；烯醇的反应：α-H的活性；醛酮的α卤代反应；羧酸的α-溴代反应；α-H的酸性：烯醇负离子的形成；烯醇负离子的反应；烯醇负离子的烃基化；羰基化合物的缩合反应机理；醛酮的缩合反应－Aldol缩合；Aldol缩合产物的脱水反应； Cleisen 酯缩合反应；麦克尔加成反应。

The stability energy of the whole complex, and the interaction energy between two purine bases and the [Pt-(NH3)thiazole]2＋ group were adopted to study the interplay among subsystems and their contribution to relative stability of all the studied cross-link model.

本文采用化合物整体稳定化能，两个嘌呤碱基与[Pt-(NH3)thiazole]2+部分的相互作用能来研究不同部分间的相互作用及其对加合物的相对稳定性的影响。

The target compounds were obtained in high yield through Michael conjugative addition of amines to methyl acrylates, cyclocondensation of the obtained diadducts in the presence of sodium methoxide,and decarboxylation of the cyclocondensation products in acid.

以胺类化合物为原料，与丙烯酸甲酯经过两次Michael加成得到N，N 二丙酸甲酯类化合物，该化合物在甲醇钠存在下进行环合，在酸性条件下脱羧，高收率得到4 哌啶酮类化合物，从而证明了这是一条合成N 取代 4 哌啶酮类化合物的普遍方法。

Niobic acid as a solid catalyst can be directly applied in the hydrolysis, esterification, condensation and alkylation reaction etc.

铌酸可直接作为固体催化剂，应用于水解、酯化、缩合、烷基化等反应中；铌酸也作为载体负载金属，应用于F-T合成、氧化反应和加氢等反应中；含铌化合物也可作为负载型催化剂，负载到不同类型的载体上；含铌化合物也作为助剂或光催化剂，广泛地应用于催化多种化学反应。

We have presented a practical method for the preparation of propargylic alcohols from terminal alkynes and carbonyl compounds promoted by KOH in the presence of 18-crown-6,and subsequent efficient cyclizations of propargylic alcohols with 2-naphthol catalyzed by InCl_3·4H_2O under the solvent-free ball-milling conditions.Ball milling exhibits its superiority over the reported methods in the preparation of propargylic alcohols and naphthopyran derivatives.

采用机械研磨方法进行了连续的两步固相化学反应的研究：首先，在氢氧化钾和18-冠-6的作用下，端基炔和羰基化合物在机械研磨条件下反应可以高效地生成相应的炔醇化合物；其次，在四水合三氯化铟的催化作用下，生成的炔醇化合物和2-萘酚在机械研磨条件下环加成生成相应的萘并吡喃产物。

Quinonyl compounds were reducted to phenolic compounds in high yields promoted by aluminum triiodide ,and after the reaction with dienophiles in Diels Alder reactions concave adductions were combined.

在现场制备的三碘化铝促进下，醌类化合物发生还原反应以良好产率生成酚类物，并且在原位与亲双烯体发生Diels Alder反应从而生成凹状加合

Through salification, esterification, hydrogenation, condensation, oxidation and halogenation etc.,LA can produce useful chemicals and new polymer materials.

同时它具有良好的反应活性，通过成盐、酯化、加氢、缩合、氧化和卤化等化学反应，可制得各种各样有用的化合物和新型高分子材料，因此乙酰丙酸有望成为一个基于生物质资源的新平台化合物。

The effects of phenolic acid compounds in vegetables and fruits on metabolicactivation of BaP in rats,as well as 〓 and TCA induced lipid peroxidation inmouse and Salmonella typhimurium TA104 cells were investigated using DNAadducts as a biomarker to assess DNA damage induced by xenobiotic carcinogens.BaP was used to study the genotoxic carcinogenesis,while 〓 and TCA were usedto study the non-genotoxic carcinogenesis.The possible protection mechanisms ofphenolic acid compounds on DNA damage were studied.

本研究根据化学致癌过程的遗传毒性和非遗传毒性机理，以DNA加合物作为机体接触外来化学物而导致DNA损伤的生物学标志物，通过观察酚酸类化合物对大鼠体内BaP活化代谢以及〓和TCA诱导小鼠肝微粒体脂质过氧化的影响，及酚酸类化合物对BaP和TCA诱导的沙门氏菌TA100和TA104形成DNA加合物的影响，探讨蔬菜、水果中酚酸类化合物对外来化学物诱导的DNA损伤的保护机制。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。