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For very long time, many research groups focus on using more than a stoichiometric amount of a chiral auxiliaries to obtain high enantioselectivity. There were mainly two sorts of processes reported on highly catalytic asymmetric addition of Grignard reagents to aldehydes. The former case was to transform Grignard reagent RMgX into other organometal reagents such as R_2Zn and R-Ti derivatives via complicated procedures at extremely low temperature. The later case was to link a chiral ligand to Mg in the form of organomagnesium amides or use chiral amine ligand catalyzing the alkylation of aldehydes.

格氏试剂对醛的不对称加成的报道大多需要大量的手性助剂以获得高的光学活性，而高度催化的格氏试剂对醛的不对称加成主要通过两种途径进行：一种是把格氏试剂转化成其他的有机金属试剂如R_2Zn和R-Ti化合物再对醛进行加成，反应通常在低温下进行；另一种是利用手性镁胺作为中间体或直接用手性胺催化来完成此反应。

In this paper,the mechanical properties of the old PCC pavement structure overlaid with AC was analyzed with ANSYS,a software for finite element analysis,and the influence of interlayers,depth of AC-overlay and modulus of AC-overlay was taken account.According to the study it could be concluded that in order to retard the reflective cracking the interlayer should be put below the overlayer and the interlayer of high modulus can take effect well.

结合试验路实体工程，采用有限元方法分析了土工布、玻璃纤维网对旧水泥混凝土路面沥青混凝土加铺层复合式路面结构的内力影响，发现为防治旧PCC路面的接缝/裂缝在AC加铺层内产生反射裂缝，宜在加铺层底部铺设夹层，且模量较大的玻璃纤维网效果更好。

objective trimetazidine has shown anti-ischemic properties to improve exercise tolerance without haemodynamic effects and direct cyto protective effect on the myocardium.however,it is not clear whether trimetazidine has beneficially effect on severe ischemic cardiomyopathy.methods 19patients（68±9）years with postnecrotic left ventricular dysfunction（ejection fraction31.7%±5.4%）were studied to examine the benefit of adding60mg a day of trimetazidine for3months to the classical therapy.the assessment included clinical evaluation,electrocardiography and echocardiography.results after adding60mg a day of trimetazidine for3months,attack of angina was relieved and dyspnea was improved（p.05）.but heart rate,systolic blood pressure,rate pressure product,ejection fraction,left ventricular volume and global wall motion index were not changed.conclusion trimetazidine seems to improve clinical status while can not change oxygen supply-to-demand ratio without adverse effects in patients on severe ischemic carˉdiomyopathy.

目的 曲美他嗪是一种新型的抗心肌缺血的药物，能够改善患者的运动耐量和心肌的直接保护作用同时并没有血流动力学效应。但目前对于严重缺血性心肌病患者的临床治疗价值还需要进一步观察。方法 19例（68±9）岁确诊为缺血性心肌病（左心室射血分数0%）的患者在常规治疗的基础上加用每日60mg曲美他嗪治疗3个月，随诊观察患者临床情况以及超声心动图指标的变化。结果 19例患者均可耐受在常规治疗基础上加用每日60mg曲美他嗪的治疗，随诊发现患者心绞痛发作明显减少，运动耐量明显改善。同时患者心率、收缩压、心率血压乘积、左心室射血分数、左心室容量以及整体室壁运动指数无明显改变。结论缺血性心肌病的患者在常规治疗基础上加用曲美他嗪是安全的，同时其能明显改善患者的临床状态，而这种作用并不改变心肌氧的供求比值。

After preapplication of OT, the Kd value for GABA-activated currents decreased, while the response obtained at the maximum concentration increased.

4预加OT后，GABA激活电流量－效曲线的粗值降低，最大反应浓度增加。(5)预加OT和未预加OT的电流－电压曲线显示，其翻转电位均在0mV左右。

Psychokinetic burst weapons deal+1d10 points of bonus damage on a successful critical hit. If theweapon's critical multiplier is ×3, add +2d10 points of bonus damageinstead, and if the multiplier is ×4, add +3d10 points of bonus damage.

爆破武器成功重击时伤害有+1d10加值，若该武器的重击倍数是×3，改为+2d10加值，若该武器的重击倍数是×4，改为+3d10加值。

Modified Kaixin Powder, modified Kaixin Powder with Ramulus Uncariae Cum Unciscould be good at enhancing VD rats" memory; Tacrine could be good at enhancing VD rats"learning; In a woed, modified Kaixin Powder, modified Kaixin Powder with Ramulus UncariaeCum Uncis could enhance VD rats learning and memory as well as Tacrine.

开心散、开心散加钩藤擅长改善VD大鼠的记忆能力；他克林擅长改善VD大鼠的学习能力；总体来说，开心散、开心散加钩藤改善VD大鼠学习记忆的能力与他克林相似，临床可辨证加减使用； 3。

Results: The optimized extract's technological parameters were: refluxed three times by 75% ethanol, five times ethanol at first, then four times and four times separately as solvent added, for one hour at each reflux.

结果：优化的最佳提取工艺为取牡丹皮等药味，用75%乙醇加热回流三次，第一次加75%乙醇5倍量、第二次加4倍量、第三次加4倍量，每次回流1小时。

In this experiment, COD removement is used as the macro-index to reflect the change of the activity of microbial indirectly and we expect to find the optimum concentration of the growth of microbial in the biological treatment system of sewage.

通过对比试验表明：(1)投加金属盐MnCl_2·4H_2O能够在一定程度上提高污水COD的去除率，在锰离子的投加量为0.5mg／L时，加药反应器COD去除率相对于对照桶COD去除率有4.3个百分点的提高。

Experiments are done. The results of experiments are satisfactional and consistent with theory. The results of experiments indicate the design of the hydraulic loading is right.

利用所开发的单片机测控系统对液压加载系统进行了阶跃响应和频域响应试验研究，试验结果表明，液压加载系统完全能满足液压悬挂系统的要求，并且与理论分析结果一致，说明液压加载系统的设计和控制方法是正确的。

Purpose: To explore further improvement of method in treating anus fistula, by observing curative effect of incision thread-drawing adding hemostasis by compression and sutura in anus fistula, and comparing the cure effect of treatment group with control group, so that the cure effect of incision thread-drawing adding hemostasis by compression and satura was verified and was affirmed.

目的：通过观察切开或切开挂线加缝压止血法治疗肛瘘的疗效，并将切开或切开挂线加缝压止血法与切开或切开挂线法的疗效进行对照比较，对临床治疗肛瘘的方法进一步改进进行初步的探索，验证从而肯定切开或切开挂线加缝压止血法在肛瘘治疗中的作用。

She gently rebuff ed him, but agreed that they could be friends

她婉言拒绝了，但同意作为朋友相处。

If in the penal farm, you were sure to be criticized.

要是在劳改农场，你等着挨绳子吧！