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(1) cerebral ischemical reperfusion injury rats'limbs motor function is variable. Acupuncture could promote lims'functional recovery.(2) PCNA masc cells is visible in cerebral ischemical semidarkness region. There is cell regeneration phenomenon. Acupuncture could strengthen injury region's PCNA expression, could profit injury recovery and functional reconstruction.(3) In ischemia semidarkness region for the model group and acupuncture group, PCNA masc cells percentage of 14days group is lower than 7days group. Along with the recovery of injury, cell multiplication is weaken.(4) In cerebral ischemia semidarkness region, there is VEGF masc cells and regeneration phenomenon. Acupuncture could strengthen injury region's VEGF expression, could profit protection after injury and blood vessel regenerate.(5) In ischemia semidarkness region for the model group and acupuncture group, VEGF masc cells percentage of 14days group is lower than 7days group. Along with the recovery of semidarkness region, ischemia and anoxemia state is getting improved, and VEGF is reduce.(6) As there are PCNA and VEGF masc cells in brain injured region, we could conclude that, after brain ischemical reperfusion injury, there are blood vessel regeneration phenomenon. Acupuncture could promote blood vessel regeneration, recovery blood supply sufficiently and quickly, and promote the recovery of brain injury region.(7)The VEGF masc cells percentage of inhibitor group is lower than acupuncture group. It state that the effect of acupuncture promote VEGF is partly depend on the existing of eNOS.

实验结论:(1)脑缺血再灌注损伤后大鼠的肢体运动功能发生改变,针刺可以促进肢体功能恢复;(2)脑缺损伤区可见PCNA阳性细胞,存在细胞再生现象,针刺可以增强损伤区PCNA的表达,有利于损伤的修复和功能重建;(3)针刺组和模型组14d时缺血损伤区PCNA阳性细胞百分比低于7d组,随着损伤逐渐得到修复,细胞增殖现象减弱;(4)脑缺血损伤区可见VEGF阳性细胞,存在内皮型细胞再生现象,针刺可以增强损伤区VEGF的表达,有利于脑损伤后保护和缺血区血管再生;(5)针刺组和模型组14d时缺血损伤区VEGF阳性细胞百分比低于7d组,随着缺血损伤的修复,缺血缺氧状态得到改善,产生的VEGF减少;(6)由于脑损伤区同时出现PCNA阳性细胞和VEGF阳性细胞,前者是增殖细胞的标志,后者是促进血管再生的重要因子,可以推断,脑缺血再灌注损伤后脑内存在血管再生现象,针刺可以促进损伤区的血管再生,更迅速而充分的恢复损伤区的血供,促进脑损伤区的修复;(7)抑制剂针刺组脑损伤区VEGF阳性细胞百分比与针刺组相比有不同程度的降低,说明针刺促进缺血损伤区VEGF表达部分依赖eNOS的存在。

Results as bellows: AtSIRT1 was located in Mitochondrial as hSIRT4 of human, and maybe take part in respiration and electron transformation chain, AtSIRT2 was located in nucleolus as hSIRT6 of human, maybe play important role in extend lifespan;mutation in AtSIRT1 leaded to cotyledon of plant turn to yellow and caused short life span. Mutation in AtSIRT2 could make the color of leaf turn to purple and accumulate a lot of anthocyanin;Sirtinol, a inhibitor of SIRT which did not cause the same model of the mutation of AtSIRT1 and AtSIRT2 indicated that the mechanism of Sirtinol was different from other organism;the structure of AtSIRT1 and AtSIRT2 were similar to other known Sir2, which indicated that they maybe have the same function;AtSIRT2 was overexpressed and its activity was detected.

结果表明,1,拟南芥AtSIRT1与人的同源蛋白hSIRT4相同,定位于线粒体,可能参与呼吸作用和电子传递,SIRT2与人的同源蛋白hSIRT6相同,定位于细胞核,可能同它的功能类似,在延缓衰老及调节细胞寿命方面起作用。2,AtSIRT1突变,可引起幼苗和植株的子叶变黄和早衰;AtSIRT2突变,可引起叶片发紫,沉积大量花青素。3,SIRT蛋白的抑制剂Sirtinol不能表型模写AtSIRT1和AtSIRT2突变体,说明Sirtinol在拟南芥中的作用机制不同于其他生物。4,AtSIRT1和AtSIRT2蛋白质结构预测表明与已知的Sir2蛋白相似,揭示其功能的相似性。5,在大肠杆菌中过量表达了其中一个基因(AtSIRT2),可体外检测其酶学活性,进一步证明其功能。

The course will start with an overview of the central and peripheral nervous systems, the development of their structure and major divisions. The major functional components of the CNS will then be reviewed individually. Topography, functional distribution of nerve cell bodies, ascending and descending tracts in the spinal cord. Brainstem organization and functional components, including cranial nerve nuclei, ascending / descending pathways, amine-containing cells, structure and information flow in the cerebellar and vestibular systems. Distribution of the cranial nerves, resolution of their skeletal and branchial arch components. Functional divisions of the Diencephalon and Telencephalon. The course will then continue with how these various CNS pieces and parts work together.

这门课将会从中枢和周边神经系统构造的发展和主要的分化点来概述,中枢神经系统的主要功能将会在复习中个别地说明:神经细胞体的断层以及功能性的分布、脊髓内上升和下降神经束的特征学和功能分布;脑干组织和功能要素,包括脑神经核、上升和下降神经束走向、含胺基酸脑激素细胞的分布、小脑和内耳前庭系统的构造和资讯传导流;颅神经的分布、骨弓和腮弓的演化;间脑和终脑的功能与分类;这门课将会探讨这些不同的中枢神经系统如何一起作用。

The information integrated pattern based on PDM/PLM in the course ofmanufacture is put forward. Under the constraints of building CAPP platform, thearchitecture of CAPP platform is established. The models of decision making andfunction for process planning are given. Then the development means of CAPP basedSmarTeam are extracted.3. The structure of modular product life cycle is established. Toward the divisionand planning of the General Modules oriented product family, theCAD/CAPP integrated model of flexible module based on feature and CAD/CAPPmapping model based on process planning match board are set up. The keytechnologies of Solidworks/SmarTeam/CAPP integration are studies.4. From the point of view of process match board and step match board, theprocess of creating to process planning match board is studied. As an example, themachining process planning of up beam of hydraulic press machines is used tointroduce the establishment of process planning match board by means of inferencebased on expert knowledge. The organize model about the process planning matchboard oriented product family is brought forward.5. The multi-decision methods of CAPP system based on analytic hierarchy aregiven.. On the basis of uniform data model, the sub-machining process planning ofpart is auto-created by means of analytic hierarchy, The step decision methods basedon AHP is put forward.6. For the design/manufacture information in the course of product life cycle, thetree structure based on Object-Oriented and static model based UML are founded. Themethod of establishing design/manufacture information management system isbrought forward. The commercial PLM software—SmarTeam is regarded asdevelopment platform, on basis of which, the design/manufacture informationmanagement system is built, and the multi-view mapping technique ofdesign/manufacture information model is studies.7. A computer-aided CAPP platform based on PDM/PLM is founded, and itsstructure, function, work flow is illustrated. Some example of the system areintroduced.

阐述课题提出的目的和意义,明确了本文研究的主要内容。2、提出基于PDM/PLM的制造过程信息化集成模式;在平台式CAPP系统的设计约束模型基础上,构建了平台式CAPP系统的体系结构;并给出工艺决策模型和功能模型;最后提出基于SmarTeam的CAPP开发模式和实现策略。3、建立模块化产品生命周期模型的组织结构;针对面向产品族的广义模块的划分和规划方法,建立基于特征的柔性模块CAD/CAPP集成模型及基于工艺模板的CAD/CAPP映射模型;研究Solidworks/SmarTeam/CAPP集成的关键技术。4、从工序模板和工步模板的角度研究了工艺模板的创建过程;以液压机上梁模块机加工为例,采用基于专家知识的推理技术实现了工艺模板的创成;提出了面向产品族的工艺模板分层结构树的组织模式。5、提出基于分层规划的多模式工艺决策流程;在统一数据模型的基础上,从特征层和零件层分层规划,实现了零件加工子工艺的自动创成;提出基于AHP的工步排序决策方法。6、针对产品生命周期中的设计/制造信息,建立了面向对象的类树结构和基于UML的静态结构模型;提出基于PDM/PLM软件的设计/制造信息管理系统的构建方法;以商品化PLM软件SmarTeam作为开发平台,开发了基于SmarTeam的设计/制造信息管理原型系统;研究设计/制造信息模型多视图映射机制。7、开发了基于PDM/PLM的平台式CAPP原型系统,构建了系统的功能模型,并对系统的主要功能进行说明,给出系统的运行实例。

Progress is impeded by a number of philosophical mistakes, and the aim of this paper is to remove nine of those mistakes: consciousness cannot be defined; consciousness is subjective but science is objective; brain processes cannot explain consciousness; the problem of 'qualia' should be set aside; consciousness is epiphenomenal; consciousness has no evolutionary function; a causal account of consciousness is necessarily dualistic; science is reductionistic, so a scientific account of consciousness would show it reducible to something else; and an account of consciousness must be an information processing account.

这个过程被某些哲学错误所阻碍,此论文目的是移除这些错误中的九个:意识无法被定义;意识是主观的但科学是客观的;大脑程序不能说明意识;&感质&的问题不应予以理会;意识是副现象的;意识并无演化的功能;意识的因果说明必须是二元的;科学是还原论式的,所以意识的一个科学式说明将显示,它可以被还原到某种其他事物上;以及意识的一个说明必须是一种资讯处理的说明。

In this study, the genomic structure and regulatory elements of ApoD from 10 representive species including protozoan, invertebrate, protochordate and vertebrate were analyzed and compared. The genomic structure of ApoD is less conserved in organisms from protostome to deuterostome invertebrates, while it is highly conserved among chordates including amphioxus and verebrates. All four conserved cysteine residues are present in amino acid sequence of deuterostome ApoDs, while there are only two cysteine residues in amino acid sequence of protostomes ApoD. Structure divergence between protostome and deuterostome ApoD proteins suggests their function difference. The majority of regulatory elements are present in nearly all organism ApoD genes ranging from unicellular protozoan to mammals, suggesting that ApoD plays a very fundamental role, and possesses a conserved regulatory mechanism. However, there also exist some specific regulatory elements, which are present only in certain species and may perform some special roles.ApoD mRNA expression in murine NIH/3T3 fibroblasts exposed to various stresses such as as hydrogen peroxide and UV light shows dose-dependent increase. And a fly homolog of ApoD, Glial Lazarillo, whose overexpression results in increased resistance to hyperoxia as well as a extension of lifespan under normoxia and resistance to starvation without altering lipid or protein content.

本文首先从生物信息学角度对分属于原生动物、无脊椎动物、头索动物和脊椎动物类群的10种动物ApoD的基因结构及调控区的调控元件进行分析及比较,发现:(1)ApoD基因外显子-内含子结构从原生动物草履虫到原口动物再到后口动物海胆的进化过程中不保守,但在分析的几种脊椎动物中相当保守;(2)文昌鱼ApoD基因扮演从无脊椎动物到脊椎动物承上启下的角色,可能代表了脊椎动物ApoD基因原型;(3)四个半胱氨酸保守位点在后口动物中都存在,而在原口动物中只存在两个,原口、后口动物ApoD蛋白一级结构上的差异反映蛋白功能上可能也存在一定差别;(4)调控区大多数主要调控元件为不同动物共有,说明ApoD主要功能及其表达调控在进化中相当保守;(5)ApoD基因个别调控元件是随着物种进化而出现并开始发挥相关作用,如SF-1;还有一些调控元件在进化过程中还没有发现其规律,这说明ApoD某些功能和基因表达调控模式可能因物种不同而存在一定的差异。

With the topic mark'yn', are put at the beginning of a sentence.

两种语言的这种结构不但其范围相当,所表现出来的功能也非常相似,而这种功能的核心就是构成突出的&话题—说明&的结构,说话人把自己要说的对象放在句首位置,在句子的其他部分对它进行说明。

According to hardware modules, the article starts description of the hardware modules schematic for detailed analysis, the combination of practical application note here is how to design the hardware, why this design and the advantages and disadvantages of this design.

文章按照产品的各硬件功能模块进行展开说明,介绍硬件功能模块时,对硬件功能模块原理图进行详细分析,结合各种实际应用的情况说明此处硬件是怎样设计的,为什么这样设计以及这样设计的优缺点。

According to hardware modules, the article starts des cription of the hardware modules schematic for detailed analysis, the combination of practical application note here is how to design the hardware, why this design and the advantages and disadvantages of this design.

文章按照产品的各硬件功能模块进行展开说明,介绍硬件功能模块时,对硬件功能模块原理图进行详细分析,结合各种实际应用的情况说明此处硬件是怎样设计的,为什么这样设计以及这样设计的优缺点。

This shows cold body weight, because the stomach territory, the main yellow, pale yellow when the note bad digestion, fat, dark, cold re-explain, then, can not eat cold things.

这说明体内寒重,因为胃属土,主黄,面色发黄时说明消化功能不好,发暗时说明寒重,这时,就不能再吃寒冷的东西了。

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Singer Leona Lewis and former Led Zeppelin guitarist Jimmy Page emerged as the bus transformed into a grass-covered carnival float, and the pair combined for a rendition of "Whole Lotta Love".

歌手leona刘易斯和前率领的飞艇的吉他手吉米页出现巴士转化为基层所涵盖的嘉年华花车,和一双合并为一移交&整个lotta爱&。

This is Kate, and that's Erin.

这是凯特,那个是爱朗。

Articulate the aims, objectives and key aspects of a strategic business plan.

明确的宗旨,目标和重点战略业务计划。