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Furthermore, marked neuronal degeneration and death occurred both in KIF 1A mutant mice and in cultures of mutant neurons.

在神经系统,突触小泡前体的运输水平大大地下降了,另外,在KIF1A基因剔除的小鼠及神经细胞培养中,均出现明显的神经元退行性改变及死亡现象。

In addition to these basic components, the conditional gene targeting construct had two loxp placed in the same orientation flanking the essential functional part of KIF1A gene-an exon which contains a ATP-binding consensus P-loop of the motor domain. We also carried a number of important considerations that have to be taken into account to generate a successful design for a KIF 1A conditional null allele.

除了上述基本特点之外,条件性基因剔除更主要的特点是,插入了3个方向相同的loxp位点,其中两个夹住了KIF1A的一段基本功能单位—一个包含了KIF1A运动区中和ATP结合的P-loop的外显子部位。

At last, using the dual-porosity model, which is provided by LOGES logging interpretation system, two parameters of gas saturation and irreducible water saturation are used to help identify the doubtful pays with low resistance.

首先校正测井仪器或测井环境对曲线质量的影响,在此基础上进行标准化处理;然后通过&四性&关系研究,考虑到涩北气田储层欠压实等影响,采用补偿密度—电阻率交会的方法来编制气层解释图版,先对曲线进行一次解释,将易于识别的测井响应特征明显的气层剔除出来,然后对低阻可疑气层进行二次定量识别;最后,借助于LOGES测井解释系统提出的双孔隙度模型,利用可动水饱和度和地层水含气饱和度相结合建立新的测井解释标准,进而准确识别低阻可疑气层。

Gome, one of the mainlands largest electronics retailers, was removed from the hang seng china enterprises index and hang seng composite/freefloat index series wednesday.

内地最大电器零售商之一国美电器已于24日被剔除出恒生中国企业指数和恒生流通综合指数。

The researchmethodology system is as follows:The variables that can be measured and have significance to stock relative intrinsic value are industry characteristic, profitability,development potential,qulity of earing and asset, the expandable potential of capital stock,the ability to pay off the debt,asset manging ability and the scale of the capital stock;(2)When the MFPM is established, the original variables should be disposed beforehand;(3)As for the research objects.we should value synthesizationly the achievement of the listed,and take the No.

本章所建立的研究方法体系为:(1)上市公司个股基本面因素中可以量化,并且对股票相对内在价值有重要影响的主要有行业特性、盈利能力、成长性、盈利质量及资产质量、股本扩张潜力、偿债能力、资产运营效率和股本规模大小等方面;(2)在建立MFPM模型时,原始指标值是不能直接用于模型计算的,必须对数据进行预处理后才能用于模型中:(3)在确定研究对象时,需要对上市公司经营绩效进行综合评价,在剔除主要靠未来业绩预期定价的第Ⅳ类股后,把第Ⅰ、Ⅱ和Ⅲ殴作为模型研究对象;(4)在选择多元回归模型时,由于原始自变量由于存在错综复杂的关系,尽管对原始自变量进行过预处理,但自变量指标依然会存在一定的多重共线性,为此在建立MFPM模型时,须采用逐步回归模型;(5)在检验MFPM模型有效性时,须从统计意义和投资实战意义两个方面进行。

If society stops using wolds, then they are taken out of the smaller dictionaries," he added."

社会停用的词汇会被从小词典中剔除,&他补充道。&

Videogame and book publishers tout units sold, which removes rising prices from the equation but still can create new chart toppers because of population growth.

视频游戏和图书出版商渲染的是销售量,这就剔除了价格上涨的因素,但人口增长的因素仍可以制造出新的榜上佼佼者。

First, sequential tomograms of the hip are obtained from a CT scan; secondly, an accurate and automatic method is used to extract the profile of the acetabulum; thirdly, a hybrid method is utilized to gather fiducial marks on the acetabulum; fourthly, bulky error sampling points are removed. Finally, an ellipsoid fitting method is used to fit the ellipsoid model of the femoral head. Two male sufferers with different necrosis extents are chosen as experimental subjects for contrastive simulation.

首先利用一种精确的自动分割方法在髋骨部位CT序列图像中提取髋臼轮廓;然后使用基于等距栅格采样法与辐条式采样法相结合的混合采样法得到髋臼凹面的空间坐标点集,并剔除其中的误差采样点;最后采用基于二次曲面一般方程的方法拟合原始股骨头椭球面模型。

Both aim to avoid pepetatingdeleteious taits by caefully selecting beeding pais andculling any animals that cay genetic anomalies.

两者都通过精心选择交配繁殖的对子,剔除任何携带异常基因的动物的方法,达到避免劣性这一目的。

But when you look at what we spend each year on removing the follicular sproutings from our faces –£320m a year in the UK on razors alone – you start to realise there's a Frucool rationale for nursing a jaw warmer into life.

但是当你看到,我们每年单独花费3亿2000万英镑在剃须刀上以剔除毛囊的萌芽,你就开始认识到Frucool生活存在的理由。

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It has been put forward that there exists single Ball point and double Ball points on the symmetrical connecting-rod curves of equilateral mechanisms.

从鲍尔点的形成原理出发,分析对称连杆曲线上鲍尔点的产生条件,提出等边机构的对称连杆曲线上有单鲍尔点和双鲍尔点。

The factory affiliated to the Group primarily manufactures multiple-purpose pincers, baking kits, knives, scissors, kitchenware, gardening tools and beauty care kits as well as other hardware tools, the annual production value of which reaches US$ 30 million dollars.

集团所属工厂主要生产多用钳、烤具、刀具、剪刀、厨具、花园工具、美容套等五金产品,年生产总值3000万美元,产品价廉物美、选料上乘、质量保证,深受国内外客户的青睐

The eˉtiology of hemospermia is complicate,but almost of hemospermia are benign.

血精的原因很,以良性病变为主。