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In order to improve the resection rate, decrease the operative mortality, complication morbidity and it is important to pay great attention to the unspecific symptoms of the epigastrium, Combined adoption of the current advanced imaging methods could result in increasing early diagnosis and essential for accurate determination of tumor resectability and operation designing. It is also important that a professional surgeon team should be organized too.

腹部非特异性症状结合影像学检查可提高壶腹周围癌的早期诊断率;术前准确评估手术可切除性,制订合适的手术方案,以提高壶腹周围癌的手术切除率,降低手术死亡率、并发症发生率。

Clinical manifestations are soreness on epigastric region, decreased appetite, distention after meal and eructation. It belongs to "epigastric pain" and "Stomach Pi syndrome" in TCM with characteristics of repetition and pertinacity. In 1978, WHO listed chronic atrophic gastritis as precancerous lesions of gastric cancer because its complications of intestinal metaplasia and dysplasia are closely related to gastric cancer. This has been a research focus in clinical practice and pathology for years.

临床主要表现为上腹隐痛、食欲减退、食后饱胀、嗳气等,属中医学"胃脘痛"、"胃痞"等范畴,具有反覆发作、迁延难愈的特性。1978年WHO将慢性萎缩性胃炎列为胃癌的癌前状态,而在其基础上伴发的肠上皮化生(Intestinal metaplasia,IM)和域异型增生(DYSplasia, DYS),则与胃癌的发生关系密切,被视为癌前病变(Precacerous lesions Of gastric cancer, PLGC)多年来始终是临床及病理学研究的重点。

The floral primordium is initially circular, along with the edge of which slight concaves occur. The outmost whorl of tepal primordia arises as a result of apical meristem division and the floral primordium then is in the shape of triangle. Two further whorls of tepal primordia arise in spiral acropetal sequence and are alternately arranged. When the innermost whorl of tepal primordia is at the late developmental stage, the foremost stamen primordia arise almost simultaneously in spiral acropetal succession and all of the stamen primordia are ultimately arranged in a triangle-cone form. Late in stamen primordium development, carpel primordia arise as same as the young stamen primordia and grow laterally. Grooves are present on the adaxial side of each carpel and develop into ventral sutures gradually closing up.

观光木的花原基最初为近圆形,随着顶端分生组织的活动,花原基边缘处出现浅凹,形成第一轮花被片原基,此时,花原基呈三角形排列,后两轮花被片原基依次发生,与前一轮互生;在内轮花被片发生的后期,最初几枚雄蕊原基几乎同时出现,呈螺旋状向顶发生,最后排列成三角圆锥状;雄蕊原基发育后期,心皮原基开始发育,形状与发育初期的雄蕊原基相似,随后心皮原基进行侧向生长,在近轴面出现浅凹,进而发育为凹槽,形成腹缝线,最后腹缝线完全愈合。

Gray matter damage was assessed on the basis of the number of normal neurons in the ventral horn. White matter damage was assessed on the basis of the extent of vacuolation and amyloid precursor protein immunoreactivity in the ventral and ventrolateral white matter.

根据腹角内正常神经元的数目评估灰质损伤程度,而白质损伤则根据空泡形成的程度以及腹内和腹外侧白质的淀粉样前质蛋白免疫原性来评估。

The abdominal wall in the left lower quadrant, 2 finger breadths (3 cm) cephalad and 2 finger breadths medial to the anterior superior iliac spine, has been shown to be thinner and with a larger pool of fluid than the midline and is usually a good choice for needle insertion for performance of a therapeutic paracentesis.27 The right lower quadrant may be a suboptimal choice in the setting of a dilated cecum or an appendectomy scar.

在过去,常常将腹部正中线耻骨与肚脐中间定为穿刺点,现在,由于腹腔穿刺引流大量液体以及腹中部脂肪厚度增加,左下腹成为腹腔穿刺部位(表1),在左下腹部中线至髂前上棘连线上2指宽(3cm)与距髂前上棘2指宽,已经显示较中部脂肪少及腹水较多是治疗性腹腔穿刺好的首选部位27,在盲肠有扩张或阑尾切除术后瘢痕时右下腹是次选的穿刺部位,应避开腹壁下动脉,这些血管走行在耻骨与髂前上棘之间的中线然后在腹直肌中向上行走,,腹壁可见的侧支循环亦应该避开,腹腔镜检查发现侧支循环可出现在中线并且在腹腔穿刺时有导致血管破裂的风险28。

Methods Modification I:Transverse incision was chosen on epigastirc,a piece of about 3×5 cm fascil strip with pedical as well as bilateral anterior and posterior sheath of recus and peritoneum was pulled through transverse mesocolon functioning as the supporting stick of traditional loop ostomy.The colon of ostomy was buried subcutaneously,stoma was opened instantly or secondarily depending on the patients′s condition.

一、选择上腹部正中线横向切口,将腹白线两旁的腹直肌前、后鞘连同腹膜切成3×5cm的带蒂筋膜条穿过横结肠系膜并缝合固定,替代传统袢式造瘘的支撑棒,造瘘肠段埋于皮下,根据病情需要直接或二期开放造瘘口,余手术操作基本同传统袢式造瘘术。

Results There was a similar distributive pattern of Neul, PPCA and β-gal in the inner ear. Neul intense staining was observed in the cochlear spiral ganglion cells, spiral limbus, spiral ligament, vestibular ganglion cells, cristae, maculae hair cells, and weak staining in inner hair cells, outer hair cells, supplying cells of the organ of Corti and stria vascularis. The intense staining of PPCA and β-gal were observed in the spiral ganglion and vestibular ganglion cells, and weak staining in the spiral limbus, spiral ligament, stria vascularis and organ of Corti. The inner ear exhibited no staining when Neul, PPCA and β-gal were deficient, respectively.

Neul最强的染色主要在螺旋神经节细胞、螺旋韧带、螺旋缘、前庭神经节细胞及壶腹嵴、球囊和椭园囊感觉毛细胞,较弱的染色分布于血管纹和Corti器内、外毛细胞及支持细胞;PPCA和β-gal在螺旋神经节和前庭神经节细胞有较强的染色,血管纹、螺旋韧带、螺旋缘和Corti器内、外毛细胞及支持细胞呈较弱的染色反应;各自酶缺乏时内耳免疫染色消失。

The second group is testing group, after anesthetic induction, under balance circulation, control infusion speed, control the CVP value on the range of 4~5 cmH2O. Monitor and record before operation, after reperfusion, that is 10 min, 20 min, 30 min, 40 min of new liver, and the changing of CVP, PAP, PAWP before closing of abdomen, on the meantime, check serum arginase by venous blood, statistical comparison of changing value of two groups.

记录监测术前、再灌注后即新肝期10分钟、新肝期20分钟、30分钟、40分钟以及关腹前的CVP、PAP、PAWP、CCO的变化,同时抽静脉血查血清精氨酸酶,动脉血做血气分析记录pH、K将两组新肝期各时段与术前各指标的变化值做统计学比较。

To confirm the hypothesis that the pathogenic mechanism of air infusion in the circulatory system is not bubble blockade of blood vessels but the consequence of anoxia of the vital organs,different amounts of air were injected into the great sapenous vein of 22 dogs,and then heart rate,cardiac rhythm and bubble sound were monitored with a Doppler probe at the precordial region.

为探讨循环系统内注入空气致病机理,向22只狗大隐静脉内注入不等量空气并在心前区用Doppler监测心率、心律和气泡音。结果发现,维持心前区Ⅳ级气泡音的17只狗,依次出现呼吸和心率加快、心律紊乱、心率缓慢、腹式呼吸加强,其中12只狗继续缓慢注入空气至呼吸停止,任选10只狗胸外按压,8只狗复苏后行为无异常,2只狗未能复活。另2只狗呼吸停止后立即尸检,可见右心房、室、腔静脉和肺血管中有大量气泡。

Only 7% of ascitic fluid cytologies are positive50 yet cytological examination is 60–90% accurate in the diagnosis of malignant ascites, especially when several hundred millilitres of fluid is tested and concentration techniques are used.12 Clinicians should liaise with their local cytology department to discuss fluid requirements before paracentesis.

只有7%的腹水细胞学检查阳性50,不过在恶性腹水的诊断中细胞学检查准确率达60-90%,尤其是当腹水检测量达数千ml并且应用浓缩技术时。12在腹穿进行前临床医生应该与本地细胞学实验室保持联络以讨论所需要的腹水量。

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