前核

The result showed that IFN-γ was distributed over 20 nucleus of the hypothalamus, such as nucleus mamillaris medialis, nucleus pre-opticus medialis, area anterior hypothalami, nucleus ventromedialis, nucleus reunions, nucleus paraventricularis, nucleus supra optic, and etc. Many of IFN-γ positive nerve fibers were found in supra optic nucleus, paraventricular nucleus, nucleus mamillaris medialis and etc. Nerve fibers and astrocytes IFN-γ immunoreactive positive cells spreaded in paraventricular nucleus, nucleus pre-opticus lateralis, nucleus pre-opticus medialis and etc. At the same time, IFN-γ is also observed obviously in adenohypophysis and neurohypophysis. IFN-γ also expresses in follicular and corpus luteum.

结果显示，IFN-γ分布于乳头体内侧核、视前内侧核、下丘脑前区、腹内侧核、连接核、室旁核、视上核等20个核团中，各部分核团细胞着色程度深浅不一；在视上核、室旁核分泌部乳头体内侧核等有大量的阳性神经纤维；同时在室周核、视前外侧核、视前内侧核等13个核团中散布有一些阳性星形胶质细胞，与阳性神经细胞交错共存；腺垂体中腺细胞和神经垂体中神经纤维均有IFN-γ表达；卵泡和黄体中也有IFN-γ存在。

FasL immunopositive neurons were observed in cerebral cortex, especially in pyramidal neurons of lamina Ⅱ and Ⅴ, cerebellar nuclei, diencephalon, and brain stem nuclei involving pontine nucleus, vestibular nucleus, cochlear nucleus, spinal nucleus of trigeminal nerve, hypoglossal nucleus, nucleus ambiguous and reticular formation.

间脑中有FasL阳性神经元分布。在脑干，Fas主要分布于前庭神经核、迷走神经背核和三叉神经脊束核的神经元；FasL广泛分布在脑桥核、前庭神经核、三叉神经脊束核、舌下神经核、蜗神经核、网状结构和疑核。

Neuronal cell bodies and fibers with moderate mGluR7-LI were seen in the olfactory bulb,anterior olfactory nucleus,piriform cortex,septofimbrial nucleus,bed nucleus of the strial terminalis,lateral hypothalamic area,paraventricular hypothalamic nucleus,supramammillary nucleus,medial and lateral mammillary nuclei,most part of the thalamus,medial and lateral geniculate bodies,nucleus of the optic tract,red nucleus,substantia nigra,interpeduncular nucleus,pontine nuclei,lateral parabrachial nucleus,superior olivary complex,nucleus of the trapezoid body,motor nucleus of the trigeminal nerve,facial nucleus,ambiguus nucleus,cochlear nucleus,vestibular nuclei,nucleus of the solitary tract,hypoglossal nucleus,prepositus hypoglossal nucleus,medullary reticular formation,Purkinje cells of the cerebellum,nucleus raphe obscurus,intermediolateral nucleus of the spinal cord,Onuf′s nucleus and lamina X of the spinal cord.

呈中等强度染色的神经元胞体和纤维见于嗅结节、前嗅核、梨状皮质、隔伞核、终纹床核、下丘脑外侧区、下丘脑室旁核、乳头体上核、乳头体内、外核、丘脑大部分核团、内外侧膝状体、视束核、红核、黑质、脚间核、桥核、臂旁外侧核、上橄榄复合体、斜方体核、三叉神经运动核、面神经核、疑核、耳蜗核、前庭核簇、楔束外核、孤束核、舌下神经核、舌下神经前置核、中缝隐核、延髓网状结构、小脑蒲肯野细胞层、脊髓中间带外侧核、Onuf核和中央管周围灰质。

The invention concerns an artificial block comprising a central core (1) having first (11) and second (12) opposite surfaces each provided with an anvil-shaped side leg (21, 22) with a table (21A, 22A), two sloping sides (21E, 21G; 22E, 22G) and two side surfaces (21B, 21C; 22B, 22C), the tables of said side legs being arranged parallel to said first and second opposite surfaces of the core, the inclined sides of said side legs resting on third (13) and fourth (14) exposed opposite surfaces of said core, said core having fifth (15) and sixth (16) surfaces each provided with side legs and front legs shaped like a truncated pyramid with four side surfaces and one front surface (33) parallel to said fifth and sixth surfaces of the core and to the side surfaces of the side legs.

一种保护层块料，包括一个中心核体(1)，有相对的第一面(11)及第二面(12)，每一面上各有一个砧状侧凸起(21，22)，这两个侧凸起各有一个台面(21A；22A)、两个斜面(21E，21G；22E，22G)和两个侧面(21B，21C；22B，22C)，所述台面相互平行，而且平行于所述中心核体的相对的第一面及第二面，所述侧凸起的斜面支撑于所述核体的相对的可见的第三(13)和第四面(14)。所述核体还有相对的第五(15)和第六面(16)，其上各有一个锥台状的前凸起，该前凸起有四个侧面和一个前表面(33)，该前表面平行于所述核体的第五和第六面，还平行于侧凸起的侧面。

METHODS:Two hundred and seventy-one eyes of 219 patients with hard nucleus cataract, grading level IV or V, were operated with anteroposterior interceptive chop method for splitting the nucleus, and then with phacoemulsification. RESULTS:The hard nucleus of the 271 eyes were successfully routed. The average phaco time was 57.4 s.

对219例(271眼)级以上硬核白内障采取前后夹击劈核法，经充分水分离和水分层，吸除硬核前的皮质及软核后，乳化头退至前囊口上缘，劈核器轻压核下方，停止灌注让核上缘随前房变浅脱出囊袋口，乳化头顺势抵住核上缘，灌注加深前房后，乳化头滑入核后面，劈核器置核前面，前后夹击将核劈碎乳化吸出。

Cells in a part of the brain known as the ventrolateral preoptic nucleus inhibit the activity of all these neurotransmitters.

细胞中的一部分大脑称之为腹外侧视前核抑制活性所有这些神经递质。

It's the kind of technical problem that appeals to me, says the former nuclear engineer.

我喜欢的就是这样的技术难题，这位前核工程师说。

When aborted rats in group E were treated with the dose of 50 IU/g IFN-γ, expression of TNF-αin this group was compared with the other four groups, the results were as follows: Compared with group A, the nucleus pre-opticus medialis, nucleus pre-opticus mango celluaris, nucleus periventricularis hypothalami, nucleus ventromedialis hypothalami, nucleus dorsomedialis hypothalami, nucleus arcuatus hypothalami and pars intermedia had a highly expression of TNF-α, in the other nuclei of hypothalamus, neurohypophsis and adenohypophysis, the change was not significantly, the expression of TNF-αin follicle and corpus luteum were decreased distinctly, the variation in uterus was slight and no difference was exsited; Compared with group B, the expression of TNF-αin nucleus nucleus lateralis hypothalami, nucleus ventromedialis hypothalami, nucleus arcuatus hypothalami, adenohypophysis and uterus presented a remarkable enhancement, conversely, the TNF-αexpression in the nucleus pre-opticus medialis, nucleus pre-opticus suprachiasmaticus, nucleus supra-opticus, nucleus pre-opticus mango celluaris, nucleus periventricularis hypothalami, nucleus paraventricularis hypothalami, neurohypophsis, follicle and corpus luteum had been significantly decreased; Compared with group C, the nucleus pre-opticus medialis, nucleus ventromedialis hypothalami, nucleus dorsomedialis hypothalami, nucleus arcuatus hypothalami, adenohypophysis, pars intermedia and uterus had upregulated the expression of TNF-α, however, it was decreased in the nucleus periventricularis hypothalami and corpus luteum; When compared with group D, the expression of TNF-αin nucleus lateralis hypothalami, nucleus dorsomedialis hypothalami, nucleus ventromedialis hypothalami, pituitary, follicle and ovary stroma were obviously enhanced, while in the nucleus supra-opticus and nucleus arcuatus hypothalami, the situation was definitely opposite, in the other parts, the change was not significant.

外源腹腔注射50 IU/g IFN-γ后，同A组相比：E组TNF-α免疫阳性产物在下丘脑视前内侧核、视前大细胞核、室周核、腹内侧核、背内侧核、弓状核、垂体中间部显著增高，在下丘脑其它核团、神经垂体、垂体前叶较A组差异不显著，在卵泡、黄体中阳性产物表达均较A组显著降低，在子宫中表达较A组变化不明显；同B组相比：E组TNF-α免疫阳性产物在下丘脑外侧核、腹内侧核、弓状核、垂体前叶、子宫均显著增高，在视前内侧核、视交叉上核、视上核、视前大细胞核、室周核、室旁核、神经垂体、卵泡、黄体中阳性物质表达均显著降低；同C组相比：E组下丘脑视前内侧核、腹内侧核、背内侧核、弓状核、垂体前叶与中间部、子宫均显著增高，在室周核、黄体中均显著降低；同D组相比：E组下丘脑外侧核、背内侧核、腹内侧核、垂体各部、卵泡、卵巢基质均显著增高，在视上核、弓状核显著降低，在其它部位表达变化差异不显著。

When aborted rats were injected with 10 IU/g IFN-γin group D, compared with group A, expression of TNF-αinmmuopositive substance in the nucleus pre-opticus medialis, nucleus supra-opticus, nucleus pre-opticus mango celluaris, nucleus periventricularis hypothalami, nucleus paraventricularis hypothalami, nucleus arcuatus hypothalami were highly increased, conversely, the ones in the nucleus pre-opticus suprachiasmaticus, neurohypophsis, adenohypophysis, ovary were obviously decreased, the change in the uterus was not remarkable; Compared with group B, expression of TNF-αin the arcuatus hypothalami was obviously enhanced, while in the nucleus pre-opticus suprachiasmaticus, nucleus pre-opticus mango celluaris, nucleus periventricularis hypothalami, nucleus paraventricularis hypothalami, nucleus ventromedialis hypothalami, nucleus dorsomedialis hypothalami, neurohypophsis, pars intermedia, ovary, the results were on the contrary, the uterus had no significantly variation; Compared with group C, expression of TNF-αin the nucleus pre-opticus medialis, nucleus supra-opticus, nucleus paraventricularis hypothalami, nucleus arcuatus hypothalami, adenohypophysis and pars intermedia had an obviously risen trend, however, the variation in the nucleus pre-opticus suprachiasmaticus, nucleus periventricularis hypothalami, neurohypophsis, pars intermedia, follicle and corpus luteum was completely opposite, uterus had no obviously change.

外源腹腔注射10 IU/g IFN-γ后，同A组相比：D组TNF-α免疫阳性产物在下丘脑视前内侧核、视上核、视前大细胞核、室周核、室旁核、弓状核显著增高，在视交叉上核显著降低，在其它核团较A组无显著差异，在神经垂体、垂体前叶、卵巢中阳性产物表达均较A组显著降低，在子宫中的表达较A组变化不明显；同B组相比：D组TNF-α免疫阳性产物在弓状核显著增高，在视交叉上核、视前大细胞核、室周核、室旁核、腹内侧核、背内侧核、神经垂体、垂体中间部、卵巢各部阳性物质表达均显著降低，在子宫表达变化不显著；同C组相比：D组下丘脑视前内侧核、视上核、室旁核、弓状核、垂体前叶与中间部均显著增高，在视交叉上核、室周核、神经垂体、卵泡、黄体中均显著降低，子宫中表达变化不明显。

Construction of heavy chain transgenic mice and genome type analysis Linearized transgene plasmids were microinjected into pronuclei of zygotes from CBA×C57BL/6 mice, and transplamted into oviduct of pseudo-pregnant mice.

二、抗体重链转基因小鼠建立及基因型分析将线性化的质粒显微注射入CBA×C57BL/6小鼠的受精卵细胞的雄前核内，然后导入假孕雌鼠的输卵管。

With Death guitarist Schuldiner adopting vocal duties, the band made a major impact on the scene.

随着死亡的吉他手Schuldiner接受主唱的职务，乐队在现实中树立了重要的影响。

But he could still end up breakfasting on Swiss-government issue muesli because all six are accused of nicking around 45 million pounds they should have paid to FIFA.

不过他最后仍有可能沦为瑞士政府&议事餐桌&上的一道早餐，因为这所有六个人都被指控把本应支付给国际足联的大约4500万英镑骗了个精光。