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In the brain of adult rat, the positive immunohistochemical product of lSL-l (ISL-l-positive) was mainly located in the neuronal nucleus and found in discrete regions except to brain cortex, such as the Purkinje cell layer and the granular cell layer of cerebellum, the granular cell layer and the pyramidal cell layer of hippocampus, the mitral cell layer, the internal and external plexiform layer, the granular cell layer and the granular cell layer of olfactory bulb and so on, and several nuclei of the hypothalamus, midbrain and pons, such as claustrum, anterior olfactory nucleus, accumbens nucleus, caudate-ptamen, pallidum, substantia nigra, striatum, islands of Callaje, mammillary nucleus, anterior pretactal nucleus, habenular nucleus, amygdaloid nucleus, cuneate nucleus, rubral nucleus, gigantocellular reticular nucleus and so on.

在正常成年大鼠脑中,同源框基因islet-1表达产物(ISL-1)免疫组织化学阳性物质广泛分布于除大脑皮层外的神经细胞的细胞核内,ISL-1阳性神经元密集分布于小脑Purkinje细胞层和颗粒细胞层、海马的颗粒细胞层和锥体细胞层、嗅球的内丛层、外丛层、颗粒细胞层及僧帽细胞层等,另外在丘脑、中脑和桥脑的一些重要神经元核团均有分布,如,屏状核、前嗅核、伏核、尾壳核、苍白球、黑质、纹状体、Calleja岛、乳头体核、前顶盖前核、缰核、杏仁核、楔束核、红核网状巨细胞核等。

Nevertheless,as this surgical method is receiving more and more disputes,with its long-term curative effects remain further observation,it still needs ever-larger investigation.One main reason for the weak curative effects of the clinical treatment for the intractable psychopathy is the uncertainty of the pathogenesis.

难治性精神病的临床疗效欠佳,其中主要原因之一就是其发病机理还不够明确,虽然有各种环路理论和神经递质异常学说,如:由乳头体、隔区、丘脑前核、扣带回、海马、中脑被盖区、内侧嗅区构成的内侧环路功能异常学说等,但是,到目前为止,尚无任何一种学说能够完全解释精神病的发病机制。

It has a specialized technician team, including E-commerce Engineer,graphic designer,draftsman,document attacher,production supervisors,distributor and after-sales service, to meet the customers' requirement and satisfy them.

公司位于浙江省义乌市城西经济开发区,生产企业集中地,交通便利,并设有专业的电子商务人员,电脑平面设计人员,专业打样人员,生产按排人员,印前核单人员,质量跟单人员,生产管理人员,专业配送货人员及相应的售后服务跟踪,以至尽量满足小商品贸易和生产企业以外包装的设计,打样,生产,运输等服务从而达到客户的各项工作与要求。

Attract domestic and foreign customers by its fame for advanced equipment , excellent technique and considerate service. It has a specialized technician team, including E-commerce Engineer,graphic designer,draftsman,document attacher,production supervisors,distributor and after-sales service, to meet the customers' requirement and satisfy them. We provide the customers one-stop service form design, produce, post-press finishing to delivery.

公司位于浙江省义乌市城西经济开发区,生产企业集中地,交通便利,并设有专业的电子商务人员,电脑平面设计人员,专业打样人员,生产按排人员,印前核单人员,质量跟单人员,生产管理人员,专业配送货人员及相应的售后服务跟踪,以至尽量满足小商品贸易和生产企业以外包装的设计,打样,生产,运输等服务从而达到客户的各项工作与要求。

Attract domestic and foreign customers by its fame for advanced equipment excellent technique and considerate service. It has a specialized technician team including E-commerce Engineer,graphic designer,draftsman,document attacher,production supervisors,distributor and after-sales service to meet the customers' requirement and satisfy them. We provide the customers one-stop service form design produce post-press finishing to delivery.

公司位于浙江省义乌市城西经济开发区,生产企业集中地,交通便利并设有专业的电子商务人员,电脑平面设计人员专业打样人员,生产按排人员,印前核单人员,质量跟单人员,生产治理人员,专业配送货人员及相应的售后服务跟踪,以至尽量满意小商品贸易和生产企业以外包装的设计打样生产运输等服务从而达到客户的各项工作与要求。

The objectives of this study were to elucidate the normal stage of connectional development in human visual pathway so that the effects of the abnormal connection in human might be understood.

包括视网膜输出至外侧膝状体的M细胞和P细胞;视交叉的发育;膝距束终末内生长至初级视皮质;视网膜投射至顶盖前核和上丘通路的发育过程,提供胚胎中枢视觉通路连续动态形态学超微结构内容,动态观察发育性结构与人类视觉功能之间的关系。

Results Many neuronal cell bodies and fibers with dense mGluR7-like immunoreactivity were intensely distributed in the island of Calleja,hippocampus,dentate gyrus,medial habenular nucleus,olivary pretectal nucleus,zonal layer of the superior colliculus,superficial layers of the caudal spinal trigeminal nucleus,paratrigeminal nucleus,raphe magnus nucleus,raphe nucleus pallidus,locus coeruleus,superficial layers and lateral spinal nucleus of the spinal cord.

结果 mGluR7阳性浓染的神经元胞体和纤维主要密集分布于Calleja岛、海马、齿状回、内侧缰核、橄榄顶盖前核、上丘带状层、三叉神经尾侧亚核浅层、三叉旁核、中缝大核、中缝苍白核、蓝斑、脊髓背角浅层和外侧脊核。

SFO stimulation induced stable and significant drinking behavior and Fos protein expression in 8 areas of the forebrain (organum vasculosum of the lamina terminalis, median preoptic nucleus, paraventricular nucleus, supraoptic nucleus, lateral hypothalamic area, perifornical dorsal area, substantia innominata and thalamic reuniens nucleus), and in 3 areas of the hindbrain (area postrema, solitary tract nucleus and lateral parabrachial nucleus).

结果显示,刺激SFO能诱发明显的饮水行为,与此同时,前脑8个部位(终板血管器官、正中视前核、室旁核、视上核、下丘脑外侧区、穹窿周核背侧区、丘脑联合核和无名质)和后脑3个部位(最后区、孤束核和臂旁外侧核)的Fos蛋白表达明显增强。

Objective To investigate the technique in stereotactic median preoptic nucleus of rats.

目的探讨大鼠正中视前核立体定位的技术关键。

GnRH-ir fibers distribute in the various brain region from the olfactory bulb to the cerebellum. They are especially abundant in the hypothalamus, the preoptic area and the ventral telecephalon. The immunopositive reaction in precocious fish is evidently stronger than that in unprecocious fish, and there is only very weak reaction in the gonadal undeveloped fish. The differences are most obvious in the hypothalamus, but not in other areas.

性早熟大黄鱼的神经内分泌细胞对GnRH抗血清的免疫阳性反应明显,无论在细胞的数量和免疫强度都比未早熟鱼多和强,在性腺尚未发育的幼鱼脑中仅有弱的免疫阳性,这种差异在下丘脑外侧结节核及视前核处最为明显,在其它GnRH阳性部位则差异不显著。

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随着死亡的吉他手Schuldiner接受主唱的职务,乐队在现实中树立了重要的影响。

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