刺激的

I want to experience some adventurous activities.

我想来点刺激的。

A drug, C6H10N4, that is a stimulant of the central nervous system and is used chiefly as an analeptic.

戊四唑一种对中枢神经系统有刺激的药物c6h10n4，主要用作兴奋剂

You will be immersed in an intellectually stimulating atmosphere.

你会沉浸在一种智力刺激的气氛。

It takes practice to be in control of your finances and win by being the first one to buy your dream, but the consolation is the benefit of becoming financially knowledgeable in a funny and exciting way.

即使你受益不多，也可以在有趣刺激的游戏中掌握很多财务知识。

To those persons who are out of the nerves control, we use FES to generate electrical stimulation and make use of the nerve cells'response to these stimulations to transfer our artificial controlling signals. Through the stimulation of adscititious electrical current, nerve cells are supposed to generate a nerve impulse that is the same as the one induced by natural inspiration.

对于失神经控制的患者，可以采用功能性电刺激仪(Functional electrical stimulation FES)产生电刺激，利用神经细胞对电刺激的响应来传递外加的人工控制信号，通过外电流的作用使神经细胞能产生一个与自然激发引起的动作电位完全一样的神经冲动，使其支配的肌肉纤维产生收缩，从而获得运动的效果。

Results are as followed:1 Exposure of HELF cells to BP caused c-Jun activation,and increased the activity of MAPK,PI-3K,p53 and cyclin D1 pathway.2 BP-induced c-Jun activation was inhibited by dominant negative mutants of extracellular signal-regulated protein kinase or c-Jun NH_2-terminal kinase,but not by p38,impling that JNK and ERK pathways medicate c-Jun activation induced by BP.3 Overexpression of dominant-negative mutants PI-3K and Akt potently blocked phosphorylations of c-Jun and ERK,but not JNK in response to BP,suggesting that PI-3K/Akt pathway positively regulates BP-induced c-Jun activation through ERK.4 Inhibition of p53 by its chemical or molecular inhibitor markedly increased the phosphorylation levels of c-Jun,Akt and ERK upon BP stimulation,indicating that p53 negatively medicates BP-induced c-Jun activation through PI-3K/Akt/ERK pathway.5 The cell lines expressed TAM67 exhibits no significant affecting normal cell growth properties.6 TAM67 was able to significantly block G_1-S transition and subsequent cell proliferation,suggesting that c-Jun is essential for cell cycle alternations elicited by BP.7 Overexpression of TAM67 impaired BP-induced cyclin D1 activation,decreasing expression of E2F1 and pRb,indicating that c-Jun participates in the modulation of BP-induced activation of cyclin D1/pRb/E2F1 pathway.8 Stably expression of TAM67 led to the increases in the expression levels of p53 and p21,elevating phosphorylation level of p53,clearly indicating that c-Jun regulates p53/p21 pathway activation induced by BRCollectively,PI3K/Akt/ERK pathway mediated BP-induced c-Jun activation through p53-dependent mechanism.

结果显示：1BP刺激细胞可促进c-Jun活化，并伴随着MAPK、PI-3K、p53和cyclinD1通路各组成成分的活性增强。2利用MAPK通路的显性失活突变体分别阻断细胞外信号调节激酶和c-Jun氨基末端激酶活性，均可明显抑制BP诱导的c-Jun活化，但阻断p38活性对BP引起的c-Jun活化无明显影响，提示JNK和ERK通路参与调控BP诱导的c-Jun活化。3过表达PI-3K和Akt的显性失活突变体也可显著抑制BP诱导的c-Jun活化，并降低磷酸化ERK的表达水平，但对磷酸化JNK的表达水平无明显影响，说明PI-3K/Akt通路通过ERK正性调控了BP诱导的c-Jun活化。4p53的化学/分子抑制剂能使BP作用的细胞内c-Jun活性明显增加，并同时诱导Akt和ERK的磷酸化水平的升高，表明p53可通过PI-3K/Akt/ERK通路对BP诱导的c-Jun活化进行负性调控。5随后观察转染细胞的生长情况，发现TAM67对细胞正常生长和形态无明显影响。6稳定表达TAM67可有效抑制BP诱导的S期细胞数的增加，提示c-Jun在BP致细胞周期改变的过程中发挥了重要作用。7TAM67过表达能够抑制BP诱导的cyclin D1活化，降低磷酸化Rb以及E2F1蛋白表达水平，表明c-Jun参与调控BP诱导的cyclin D1/Rb/E2F1通路的活化。8过表达TAM67可使BP刺激的细胞中p53、p21总蛋白以及p53磷酸化的表达水平明显升高，可见c-Jun也参与调控BP诱导的p53/p21通路活化。

The characteristics of on-off responses of medial geniculate body neurons to tone bursts of varying frequency, intensity and duration were affected by lateral amygdaloid nucleus stimulation, which was in form of altering the pattern of discharge or complete suppression. The effect also varied with the changes of the interval between amygdaloid stimulation and the tone bursts. The results of the present work show that LAm could modulate temporal processing of auditory information.

新西兰兔内膝体神经元的on-off反应与纯音刺激的强度、频率及作用时程有关；刺激边缘系统杏仁外侧核，可以抑制on-off反应，或是使on-off反应放电构型发生变化。on-off反应是神经元对声音信号作用时程及声音的起止进行编码的方式之一，LAm对on-off反应的影响表明，边缘系统杏仁体的活动可以调控听觉中枢对声音时间信息的编码。

Therefore, in Experiment 3,A~standard Hedge and Marsh Two-Choice Responsetask were conducted,in which the relevant stimulus dimension was color and theirrelevant dimension was the location of that stimulus.

因此，本研究在实验三中进行一个更加标准的Hedge和Marsh任务，相关维度是刺激的颜色，无关的维度是刺激的位置，观察能否得到Simon效应的反转。

"It has long been known that demulcents can soothe irritated mucous membranes and thereby remove the irritation that is fueling the cough reflex," says Paul Doering, co-director of the Drug Information and Pharmacy Resource Center at the University of Florida.

对于咳嗽和咽喉疼痛，可能是蜂蜜的粘稠度和粘滞度使得它能够很好地发挥作用。&长期以来人们就知道缓和剂能够缓和受刺激的粘膜，因此消除引发咳嗽反射的刺激，&弗罗里达大学的药物信息和药学资源中心的副主管Paul Doering说。

Expression analysis with RT-PCR revealed that PcLGBP gene was exclusively expressed in hepatopancreas and the expression could be up-regulated by heat-killed Listonella anguillarum. The binding specificity of PcLGBP to ligand were subsequently examined by recombinant expression of the cDNA fragment encoding its mature peptide in Escherichia coli BL21 (DE3) and ELISA approach.

为分析PcLGBP基因的功能，通过半定量RT-PCR方法研究了其在组织中的分布，并用荧光定量PCR技术分析了其对细菌刺激的响应，结果表明PcLGBP基因是肝胰腺特异表达的基因，能响应热致死鳗弧菌刺激而增强表达，说明PcLGBP基因可能参与螯虾的细菌防御反应。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。