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This dissertation theoretically demonstrates the feasibility to achieve constant direct current-stimulation-circuitry under microampere , bring forward design scheme software and hardware system using in cellular electrical stimulation. In order to further quantitatively research on direct current-stimulation and ascertain the best intensity and density and stimulative current , the quantitative and qualitative analyse for gained diagnostic data are also been discussed in this paper.

本文正是从该理论基础出发,论证了实现微安级直流电刺激的离体组织细胞生长培养实验系统的可行性,提出了用于刺激实验的软硬件系统的开发放案,并对采集数据的定量和定性的分析作了初步的探讨,希望通过实验能够初步确定适合该组织细胞生长培养的最佳刺激电流和最佳刺激时间。

I build my research work on the pass and improved the hardware and software of experimental system, and explored some new analyzing methods to pick out the CEP signal wrapped in the EEG more efficiently.On hardware, I designed a instrument to let our testee to observe the RDS, shown on Cathode-ray tube or printed on paper, through a stereoscope, and never let the stereoscope effect the observation. The instrument includes 3 modules: RDS showing, stereoscope fixing and testee fitting.

本文对CEP研究过程中的软件和硬件环境进行研究和改进,同时通过改进CEP信号的分析方法,设计了实验者观察刺激信号寸的立体镜支撑系统,包括刺激的呈现,立体镜固定,受试者适应等模块,使得受试者能够舒适地通过立体镜观察CRT上的刺激信号或者宁丁印在纸上的刺激信号。

Experiment on adaptation effects in cat striate cortex found no pronounced difference between simple cells and complex cells.

结果显示,相对于简单的平动刺激,复杂的光流刺激引起了更显著的适应及后效应:细胞的反应在适应期间及适应后衰减程度更大,多数细胞的方向选择性在适应后发生了显著变化;总体上,细胞对复杂光流的适应具有方向选择性,但细胞对平动刺激的适应与测试刺激的运动方向无关。

The result indicates that the intracortical synaptic input was unchanged, but the thalamocortical synaptic input was depressed by sensory stimulation and this depression recovered with a time course that matched that of the recovery of sensory responsiveness.

结果表明,电刺激诱导出的皮层—皮层突触反应不受持续的触须刺激的影响,而电刺激诱导出的丘脑—皮层突触反应则由于持续的触须刺激而减小,而且突触反应的恢复时程与皮层细胞适应恢复的时程类似。

The experimental data demonstrated that there was a nasalward directional preference in oath OKN system under both close loop and open loop conditions, and the nasalward OKN gain evoked by stimulation of nasal retina was much higher than that at temporal retina. ms indicates that OKN nasalward preference is mairily derived from the nasal retina, i. e. the direct path1Vay of OKN dominates the indirect pathway in cat's OKN system. The gains of temporalward and nasalward OKN from temporal retina are much less than those of nasalward OKN from nasal retina. It is suggested that the indirect pathway of OKN in the cat only possesses a supplementary function, Which probably plays an important role in temporalward OKN eye-movments in relation to binocular vision.

实验结果显示:高速度刺激的闭环OKN反应及开环OKN反应均对鼻向运动刺激有明显的方向选择性;半侧视网膜刺激时,鼻侧半视网膜的鼻向OKN增益明显高于颞侧半视网膜的鼻向增益,说明猫的OKN眼动反应以跟踪鼻向运动为主,并且这种对鼻向运动刺激的选择性主要来源于鼻侧半视网膜,亦即来源于OKN直接通路;颞侧半视网膜的鼻、颞向眼动增益均明显低于鼻侧半视网膜的鼻向眼动增益,说明猫的OKN系统的间接通路在OKN眼动控制中起辅助作用,并可能主要对颞向OKN眼动起作用从而与双眼视觉功能相关。

The accomplished software-control system of cellular growth system based on direct current-stimulation has characteristics as below:(1)individualise treatment according to user's requirements such as stimulation-current , stimulation-time and stimulation-channel;(2) operate easily and conveniently based on friendly;(3) could enable cursor switch conveniently and quickly among input frames, and disable corresponding choices to avoid mistaken operation;(4)could analyze the gained data and display the waveform of analytical data;(5)provide set up program of the software.

已完成的细胞直流电刺激实验系统软件控制系统具有以下特点:(1)可根据用户需求选择刺激电流的强度、刺激时间和刺激的通道,同时还可对采样频率进行选择;(2)系统软件操作界面友好、美观;(3)参数设置时控制按钮的光标可以方便、快速地在各输入框间切换,并使不能操作的选项失效,减少误操作;(4)对采集到的特征数据可进行数据分析,并对分析数据进行波形显示;(5)提供了该软件的安装程序。

METHODS:By using Vision Monitor visual evoked response imaging system,the standards for five obtained Flash Electroretinogram were recorded on 53 normal subjects (73 eyes),including F-ERG to a weak flash in the dark-adapted eye,F-ERG to a strong flash in the dark-adapted eye,oscillatory potentials,F-ERG to a strong flash in t...

应用法国Metrovision公司生产的Vision Monitor视觉诱发系统检测正常人53例73眼。F-ERG的5个标准反应,包括暗适应25dB弱光刺激时的反应、暗适应0dB强光刺激时的反应、振荡电位、明适应白色标准闪光刺激时的反应和明适应快速重复闪烁光刺激的反应。

METHODS: By using Vision Monitor visual evoked response imaging system, the standards for five obtained Flash Electroretinogram were recorded on 53 normal subjects (73 eyes), including F-ERG to a weak flash in the dark-adapted eye,F-ERG to a strong flash in the dark-adapted eye, oscillatory potentials, F-ERG to a strong flash in the light-adapted eye, and F-ERGs to a rapidly repeated stimulus.

应用法国Metrovision 公司生产的Vision Monitor 视觉诱发系统检测正常人53例73眼。F-ERG的5个标准反应,包括暗适应25dB弱光刺激时的反应、暗适应0dB强光刺激时的反应、振荡电位、明适应白色标准闪光刺激时的反应和明适应快速重复闪烁光刺激的反应。

In Taylor 's hypothesis, material and spiritual stimulation, disciplinary and cultural management,visible and invisible environments are integrated successfully. Plenty of ideas about "social man" and "self-actualizing man" are enabling it to be "new economic man", which is sharply different from classical "economic man" i...

泰罗的&经济人&假设体现了物质刺激与精神刺激,外在刺激与内在刺激的结合;制度管理与文化管理,刚性管理与柔性管理的统一;硬环境与软环境,有形环境与无形环境的融合,蕴含了丰富的&社会人&、&自我实现人&的思想,本质上已区别于以往时代的&古典经济人&,成为&新经济人&。

In Taylor's hypothesis, material and spiritual stimulation, disciplinary and cultural management,visible and invisible environments are integrated successfully. Plenty of ideas about "social man" and "self-actualizing man" are enabling it to be "new economic man", which is sharply different from classical "economic man" in essence.

泰罗的&经济人&假设体现了物质刺激与精神刺激,外在刺激与内在刺激的结合;制度管理与文化管理,刚性管理与柔性管理的统一;硬环境与软环境,有形环境与无形环境的融合,蕴含了丰富的&社会人&、&自我实现人&的思想,本质上已区别于以往时代的&古典经济人&,成为&新经济人&。

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