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刺激物

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Since the mites eat sloughed off skin cell debris and the secretions in the ear canal, their feeding irritates the sensitive canal, thus causing the itching.

由于螨虫吃删去皮肤细胞碎片和分泌物中的耳道,其喂养刺激敏感的运河,从而导致瘙痒。

Upon induction of apoptosis by diverse stimuli, Bax undergoes a conformational change and translocates to mitochondria, where it oligomerizes and forms pores that allow the release of cytochrome c and other cytotoxic foctors.

在被不同刺激诱导后,Bax的构象发生改变并转移到线粒体上。在线粒体膜上,它形成低聚物并使线粒体膜形成孔,使细胞色素c和其它细胞毒性因子可以排出。

Weibel-Palade bodies are specialized cigar-shaped secretory organelles in endothelial cells, which contain a variety of biologically active molecules. These contents can be released rapidly by stimulation and involved in hemostasis, inflammation and angiogenesis.

Weibel-Palade小体(Weibel-Palade body, WPB)是血管内皮细胞一种特殊的分泌性杆状细胞器,含有多种生物活性分子,受到刺激后可以非常迅速的释放这些内容物,参与止血、炎症和血管生成等生理功能。

Second, the temptation to chase and nip running children is a risk with young Borzois.

其次,捕捉诱惑物和正在小跑的孩子对小猎狼来说是一在种刺激的冒险。

The oxygen consumption with the substrates of succinate in RTT significantly decreased by 34% as compared with that in control. RTT cybrids produced more oxygen radicals than that of control cybrids as measured by anti-cyano-respiration that reflects the production of oxygen free radicals in mitochondrial respiratory chain. RTT cybrid cell lines demonstrated an increased sensitivity to 〓-induced apoptosis as compared to control cybrids.

以琥珀酸为底物时患儿组融合细胞线粒体呼吸氧耗率显著降低,较正常对照组降低34%;患儿融合细胞线粒体呼吸链氧自由基水平增高,对〓刺激的凋亡易感性增高。

Methods:(1) Dissoluble PGN and CpG DNA were immobilized onto the surface of biotin cuvette for establishing target. Another effective tracking approach was established by immobilizing Escherichia lipid A F583 onto the surface of Non-derivatised cuvett. The biosensor technology was applied to screen anti-inflammatory TCM targeting on three key molecules.(2) The active compositions were isolated by AB-8 macroreticular resin from lycium bark. After the activities of compositions were evaluated, the most effective compositions was confirmed. In vitro, the affinities of different concentrations composition E binding with PGN, CpG DNA and lipid A were measured separately. The effect of composition E on vigor of RAW264.7 cells were tested by MTT and CCK-8, and its inhibition on TNF-α, which was released from RAW264.7 cells induced by PGN, CpG DNA and LPS, was also tested by ELISA. In vivo, murine sepsis models were made by intravenously heat-killed E.coli and heat-killed S.aureus, then protection of composition E on mice sepsis model were observed.

(1)将PGN及CpG DNA包被于生物素样品池,将lipid A包被于非衍生样品池,分别建立以PGN、CpG DNA及lipid A为靶点的技术平台,对114种抗炎中药水提物进行筛选、评价其活性物质含量,并评估出针对上述三种病原分子均具有较高结合活性的中药;(2)利用生物传感器跟踪检测技术、大孔吸附树脂分离技术,从地骨皮中定向分离与PGN、CpG DNA及lipid A均具有较高亲和力的活性组分;在体外实验中,测定不同浓度活性组分与PGN、CpG DNA及lipid A亲和力;MTT法及CCK-8法检测活性组分对RAW264.7细胞活力的影响;ELISA法检测活性组分对PGN(2μg/ml)、CpG DNA(10μg/ml)及LPS(100ng/ml)刺激小鼠RAW264.7细胞分泌TNF-α的抑制作用;在体内实验中,采用尾静脉注射致死剂量热灭活大肠杆菌和热灭活金黄色葡萄球菌,建立细菌脓毒症小鼠模型,观察活性组分对脓毒症模型小鼠的保护作用。

Malolactic fermentation is a very important processing technology for deacidificaton in modern winemaking.

苹果酸乳酸发酵是现代葡萄酒酿造工艺中重要的生物降酸手段。MLF是L 苹果酸在乳酸菌的苹果酸乳酸酶催化下转变成L 乳酸的酶促反应过程,该过程没有底物水平的磷酸化,但在MLF过程中苹果酸确实能够刺激细菌的比生长速率,增加细菌生物量。

Suitable to growth then habitually greedily to the temperature of light, to chase irritate, to flaunt self-center, and attempted to use consume and novel to be the fulfillment, also the fashion and special to cover its body, and use of the attitude and topics to zoom in spirit, to let itself becomes the lure to contest others eye bows.

适应而生长便习惯性地贪婪光的温度,追逐刺激,标榜自我,企图用消费与新奇填补满足,用时尚与独特包裹身体,用姿态与话题放大灵魂,使自己也成为了争夺别人眼球的诱惑物。

The latter would provide a lower ink weight, as well as a higher rate of polymer composition and low stimulation acidlowpolymer proportion within the health and safety features to make improvements.

后者会提供较低的墨膜重量,以及较高的高分子成分和低刺激低聚物的比重,从而在健康和安全特性方面做出改善。

Those include further properties of the correlations, features of selective cells as discriminators of stimuli provoking different delay activity distributions, and activity distributions among the neurons in a delay activity produced by a given pattern.

其中包括了进阶的关联特性、身为导致延缓活动分配刺激区分物的筛选细胞特徵,以及在给定的模式下延缓活动中神经元之活动分配。

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