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Sustained AF could be induced easily in all dogs during vagal nerve stimulation in vivo both before and after isolation of all PVs with encircling lesions created by a bipolar radiofrequency ablation clamp device. PV elimination had no effect on atrial effective refractory period or its responses to cholinergic stimulation. Autonomic ganglia were identified by bradycardic and/or tachycardic responses to high-frequency subthreshold local stimulation. Ablation of the autonomic ganglia overlying all PV ostia suppressed the effective refractory period-abbreviating and AF-promoting effects of cervical vagal stimulation, whereas ablation of only left- or right-sided PV ostial ganglia failed to suppress AF.

无论是在双极环状消融所有PV之前或之后,在体刺激颈迷走神经节过程中持续性房颤在所有犬均能轻易被诱导出,PV切除对心房肌的有效不应期或对胆碱的反应均没有影响,通过对高频的域下刺激发生快速或慢速反应来鉴定自主神经节,消融叠加于PV口部的自主神经节能抑制有效不应期的缩短、和刺激颈迷走神经诱发的房颤促进作用,而仅消融左或右侧PV口部的自主神经节却不能抑制房颤。

The response of HNEC to the stimulation of LPS shows dosage dependence, and stimulation of LPS with suitable concentration benefits HNEC secreting Th1/Th2 cell factors to maintain the balance; The stimulation of LPS with too high and too low concentrations would cause unbalanced secretion of Th1/Th2 cell factors, which might be the pathopoiesis mechanism of gram negative bacilli in chronic rhinitis and rhinosinusitis.

LPS对HNEC的刺激反应与浓度呈剂量依赖性,适当浓度的LPS刺激有利于HNEC分泌的Th1/Th2细胞因子维持平衡状态;过高或过低浓度的LPS刺激可诱导HNEC的Th1/Th2细胞因子失衡分泌,这可能是GNB在慢性鼻、鼻窦炎的致病机理。

Results When lesion was located in the spinal cord ventrally and olivo ponto OPCA cerebellar atrophy, the evoked potentials N30, P40 from C2 and occiput after stimulating tibial nerve showed simultaneously abnormal.

结果 脊髓腹侧及小脑病变可致胫神经刺激,C2、枕点 N30及P40电位出现同步性异常改变,且胫神经刺激出现异常者,正中神经刺激,C2、枕点电位却可保持正常。

The basic procedures of the experiments were:(1)rule training:thisis pretraining in order to make subjects attend gradually to the numberdimension of stimuli,and master the rule of number matching.(2)formaltraining:a variety of cards loading number"3"or"5"served as samplesand comparisons.(3)transfer test,test trials were interposed among usualtraining trials of each session,the number is from 1 to 9,and three typestransfer test were proceeded.

两个实验的基本程序为:(1)规则训练阶段:用几个步骤使被试逐渐注意刺激的数维度,并掌握数目匹配原则;(2)正式训练阶段:数目3、5的多种变式作为样本和比较刺激,通过被试在各种样本和比较刺激对上的反应分析它们所利用的线索;(3)迁移测试阶段:将迁移测验随机插入每天的正式训练中,数目扩展为1至9,以验证被试数能力的抽象程度。

Antigen-driven T cells maintained in culture using this combined cytokine regimen can be induced to grow and maintained functional in large numbers and survive long-term in cultrue with each antigen restimulation cycle prolonged to six weeks. The IL-2 doses used in this combined cytokine regimen can be reduced 10 to 100 times that of cultures using IL-2 alone.

结果表明:单独使用IL-2或IL-7均能增强T细胞对ConA或特异性抗原刺激诱导的增殖反应,但联合使用IL-2和IL-7具有更加显著的协同刺激作用。C57BL/6小鼠抗FBL-3肿瘤特异性T细胞系在IL-2与IL-7联合培养系统中,不但T细胞数量明显增加,且能在保持特异性功能的同时,延长T细胞体外抗原刺激周期。

Furthermore, the pattern of neural activity seems to be stable when the rivalrous stimuli are presented intermittently, which is known to induce stable perception in human.

研究结果显示,在有适当起始时间差的竞争性刺激下,后续刺激的作用会被先导刺激所抑制。

Results PE was found to be able to stimulate the proliferation of murine splenocyte in the absence of accessory cells. Accessory cell and its supernatant from AC stimulated with PE was able to enhance the proliferation of lymphocyte induced by PE.

结果 PE在0.01~100ng/ml浓度范围能刺激鼠脾淋巴细胞增殖,PE的丝裂原作用无需粘附细胞的辅助,但粘附细胞及其粘附细胞的PE刺激上清能协同PE对鼠脾淋巴细胞的刺激作用。

After three months of treatment, motor score improved 49% with subthalamic stimulation and 37% with globus pallidus stimulation, relative to no stimulation.

经过三个月的治疗后,与完全没有刺激的病患相较,接受丘脑下刺激的患者在运动功能测验上评分增进百分之四十九,而接受苍白球刺激的患者则增进达百分之三十七。

Objective: To evaluate the effect of different mode of high frequent stimulation in subthalamic nucleus, 5 second phasic stimulation and long lasting continuous stimulation, on EEG and behavior scale of epilepsy rat models induced by penicillin.

目的:研究不同持续方式(短程间断刺激5s和长时间连续刺激16min)的双侧高频电刺激丘脑底核对青霉素所致的大鼠急性癫痫模型的行为学分级及脑电图的影响。

Stimulation at this site is typically delivered at low frequencies in contrast to the high frequency stimulation required for therapeutic benefit in the subthalamic nucleus.

在这个位点的治疗刺激一般采用低频刺激而不是像亚丘脑核这样使用高频刺激

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