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刺激

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The fEPSP response evoked in one pathway was small, usually 20–30% of the maximu, whereas a large response, usually 80–90% of the maximum, was evoked in the strong pathway. After recording of the baseline fEPSP evoked at 0.033 Hz, LTP of the weak pathway could be associatively induced by paired stimulation of the weak and strong pathways 100 times at 6 sec intervals, with stimulation of the weak pathway preceded 3–10 msec.

在记录以0.033Hz所引发基础的兴奋性突触后电位之后,在弱的路径上可以因配合弱与强的刺激路径而引发出相关性长期增益(每六秒一次共100次,弱的刺激路径在强的刺激路径之前 3-10 ms),然而当在两个路径之间的配合时间差大於10 ms时即无法形成相关性长期增益,此类型长期增益的引发是需要依赖活化NMDA接受器的,因为给予50 mM的D,L-AP5可以阻断相关性长期增益的引发(兴奋性突触后电位为原来的105±6﹪;n=6)。

However, it is not known how orthodontic force influences the function of cementoblast and what is the relationship between the function change of cementoblast with root resorption. So we studied the effect of mechanical stimuli on root resoption by examining the expression OPG and RANKL and exploring the related signal transduction pathway in cementoblast. Methods: Cementoblasts OCCM30 were cultured in DMEM with 10% FBS for 48 hours and starved in DMEM with no FBS for 24 hours, then subjected to mechanical strain by four-point bending system with tension and compression stress at 2000μstrain at 0.5Hz frequency. The flow cytometry was used to examine the cell cycle and proliferation activity after 3h, 6h, 12h, 24h loading respectively. OPG and RANKL mRNA were analysed with real time quantitive RT-PCR after the same loading period as FCM.

本课题利用四点弯曲力学加载系统,采用流式细胞术、实时荧光定量PCR、Western免疫印迹等方法,研究体外培养的成牙骨质细胞株OCCM-30在不同力学环境中增殖活性的变化,以及其表达骨保护素和破骨细胞分化因子的mRNA的变化,探讨应力刺激对成牙骨质细胞表达破骨细胞分化调控蛋白的影响,并通过对应力刺激下成牙骨质细胞分裂原活化蛋白激酶家族中的ERK1/2、P38MAPK活性的变化及其与OPG、RANKL基因表达变化关系的研究,对力学刺激调节破骨细胞分化调控蛋白的相关上游信号转导通路进行初步探讨。

In the second experiment, dichoptic display (15 ms for single eye, 30 ms for single eye, 30 ms for both eyes) was used to investigate the mechanisms of these brightness effects.

第2个实验,采用单眼和双眼分离两种观察方式,使得刺激呈现单眼呈现15ms,单眼呈现30ms,双眼呈现30ms3种情况,在刺激呈现结束后,要求被试报告闪光刺激明暗关系。

Sand or artificial pearl nuclear in a Pinctada martensl, a shellfish, with overlapping accumulation of the excretive protein film from cells in the inner shell theca and the conjunctiva layer of calcium carbonate.

南珠的形成:南珠是珍珠贝科动物中马氏珍珠贝受刺激刺激后,外套膜的部分细胞所分泌的壳角蛋白膜和碳酸钙的结薄层交互重叠,围绕着刺激物沉积而成的圆形或其他形状的物体。

Sedation score used Ramsay Scale (Ramsay Scale: 1-sober, anxious orrestless or both; 2-sober, cooperative, orientated and tranquil; 3-sober, responding tocommands; 4-sleep, brisk response to stimutus such as percus on glabellum or loudauditory stimulus; 5-sleep, sluggish response to stimulus; 6-sleep, no response tostimulus).

镇静评分采用Ramsay评分(Ramsay Scale:1,清醒,焦虑和易激惹,或不安,或两者都有;2,清醒,能合作,定位感好,平静;3,清醒,只对指令应;4,睡眠对眉间轻叩或大的听觉刺激反应轻快;5,睡眠,对眉间轻叩或大的听觉刺激反应迟缓;6,睡眠,对眉间轻叩或大的听觉刺激无反应。)。

S Broad asphalt along the main road, followed by the array of more than 30 of its significant interest in large, medium and small Recreation: If the crazy "roller coaster" in the air on the track and came to a series of somersaults, and let you experience a soul-stirring centrifugal, rapid rotation of panic, can be done to stimulate;"fast scooters" in the track km On the fast, as Shirupozhu dive 30 meters high slope, Huer mad to Jixuan, feelings like Cloud Nine fall, as if riding a bull at running back; in particular, the addition of new large-scale projects,"Challenger Tour" Mars will give you the speed of excitement around the world,"wind speed," you over 10 meters in height, during which around and up and down several times before and after the turnover, there is a non-feet under the ultimate experience weightlessness; and the "monster House "is another boost fan, pitch dark, cold wind gusts, desperate calls and setting of zombie ghosts and volatile side of the creeps you scared, scared; 50 meters out to the" Ferris wheel "to let you enjoy the" List Small hills,"the sense of endless;" Liu Yong Jin,"When you enjoy the" drift "Huiguoshenlai no sense, as water spilled from the mountain 10 meters high fly drift down the moment, the heart Has been hanging in the air to the; also hit eyeful of Venus "bumper car"; as the mischievous people Shuaixiang half-empty,"Spider-Star,""rotating aircraft" and "forest mouse car," and so on, you will be able to bring a Although the stimulus was accompanied by tears, but more interest is the doubling of the situation, a test of your willpower.

沿着宽阔的柏油大马路,依次排列着三十多个各显其趣的大、中、小型游乐项目:如疯狂&过山车&在凌空的轨道上急转直下而又接连翻腾,让你经历一场惊心动魄的离心、快速旋转的恐慌,可谓极尽刺激;&快速滑行车&在千米的轨道上风驰电掣,势如破竹般俯冲三十米高坡,忽儿狂转急旋,那感觉仿如九霄云外下坠,又好象骑在蛮牛背上狂奔;特别是新增设的大型项目&挑战者之旅&将带给您火星绕地球的速度快感,&极速风车&,你凌驾十米高空中,其间几度上下左右和前后翻转,真有一种双脚无着下的终极失重体验;而&妖怪屋&又是另番刺激,伸手不见五指,寒风阵阵,绝望的叫声和出没无常的僵尸鬼面,吓得你毛骨悚然,胆战心惊;拔地五十米的&摩天轮&让你享受&一览众山小&的无垠感觉;&激流勇进&,当你优悠的&漂&感还没回过神来的时候,高山泻流水般从十米高处向下飞漂的那一刻,心已悬到半空中了;还有撞到满眼金星的&碰碰车&;恶作剧般把人甩向半空的&星际蜘蛛&、&旋转飞机&和&森林老鼠车&等,都能将你带到一个虽然伴有被刺激后的泪花,但更多的是兴致倍增的境地,考验了你的意志力。

Concept of subconsciousness.There are two ways for us to get information: consciousness and subconciousness. Each day we get different extent stimulations tangibly and intangibly, such stimulations waken our awareness and lead to relevant responses. Consciousness is to receive surrounding stimulations mindedly, and subconsciousness is on the contrast way. Subconciousness is the key part of psychological analysis and basis of Sigmund Freud's theory.

何谓潜意识,我们人脑接受信息的方式分为有意识和无意识接收两种方式,我们每天都会受到不同程度有形或无形的刺激,引起我们的注意而产生不同程度的反应,有意识接收是人脑地于周边事物的刺激有知觉地接收信息;而无意识接收是人脑对于周边事物的刺激不知不觉地接收,这就是所谓潜意识,它是精神分析的核心部分,是弗洛伊德的理论的基础。

Moreover, the S1 area was shown to be more easily activated and more intensively innervated by the thalamocortical afferent projections than by the intracortical connections.

其次,刺激IV层在每一刺激强度下诱发的场电位幅度远远大于刺激II-III的场电位幅度,即S1区更容易被丘脑皮层连接回路的投射纤维所激活。

To estimate the contribution of thalamocortical and intracortical synapses to rapid adaptation, we applied electrical stimulation in VPM and barrel cortex and compared the electrical evoked responses of cortical neurons before and after adapting stimulation.

为了了解丘脑—皮层突触和皮层—皮层突触对皮层细胞快速适应的贡献,实验中分别在VPM和体感皮层施加电刺激,研究持续的感官刺激对电刺激诱导出的皮层细胞反应的影响。

The shorter of interruption duration, the more obvious interruption effects, and this support the motion opponency theroy. 3 The different intervals between priming and target were detected. Due to interruption of blank frame, the shorter interruption elicited positive proming effects, which is consistant with integration of temporal and spatial in the human brain. 4 The negative of the same direction is relationship to visual adaption and visual inertia effects.

本系列实验得到以下主要结果与结论:1插入空白图片,将导致特定运动方向的反转,而对二义的运动没有明显影响,反映了空白图片对正常视觉运动的阻断;2阻断时间越短,导致特定运动方向反转的几率越大,即阻断效应越明显,支持运动知觉对立理论;3考察不同间隔的启动——靶刺激,由于空白刺激的插入,启动——靶刺激间隔较短时引起的正性启动效应,与人脑系统对视觉信号的时间与空间整合和视觉惯性是一致的。4同向运动的负性倾斜效应与视觉适应有关。

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