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We also discovered that selenium can decrease hematolysis and effects function of vacuole toxin of HP. morphological conversion from spiralto coccoid forms occurredwhen HP was caltured with selenium and most of coccoid forms had fragmentary flagella and pilus; the effection of selenium to activity of urease, catalase, alkaline phosphatase is not exist or not evidence; selenium enable pET32a-vacA-E. coli BL21 which can express VacA produce yellow lipochrome, and the color become deeper with increasing of concentration of selenium; selenium can decrease expression of recombined VacA by restrain the growth of pET32a-vacA-E. coli, but can not influence activity and gene equence of VacA; selenium can enhance the suppression effect of recombined VacA for gastric cancer cell, depress the index of cell multiplication and the forming rate of colony, decrease the number of cell in S period, increase total of cell in G period; After purified, the recombined VacA can be identified by VacA antibody.

结果:体外实验结果表明:一定浓度的硒作用HP后,HP菌落数量随着硒浓度的增加而减少,菌落颜色由灰白色变为砖红色,溶血现象随硒浓度的增加和作用时间的延长而逐渐消失,HP的形态由弯曲形变为球形或椭圆形,鞭毛及菌毛出现脱落现象;硒对尿素酶、过氧化氢酶、碱性磷酸酶活性无影响或影响不明显;一定浓度的硒能使表达VacA的pET32a-vacA-E.coli BL21工程菌产生脂溶性砖红色色素,颜色随硒浓度增加而加深;一定浓度的硒通过抑制pET32a-vacA-E.coli BL21工程菌的生长,减少重组VacA表达量,但不影响其空泡毒活性及编码基因序列;硒能增强重组VacA对胃癌细胞的抑制作用,使细胞分裂指数和集落形成率降低、S期细胞数量减少,G1期细胞总数增加;纯化后的VacA重组蛋白可被VacA抗体识别,具有良好的抗原性。

This kind of immunosuppression may be im- proved by administration of indomethacin in vivo.

进一步研究则证明,分裂原反应性的恢复与该药对抑制性巨噬细胞活性的阻断有关。

Pleomorphic giant nucleus(100%), obvious nucleoli(75%) and karyokinesis were the main elements in the smear of bone metastatic carcinoma.

骨转移性癌则以无多形性大核细胞(100%)、核仁明显(75%)、有核分裂象为主要特征。

A core needle biopsy misdiagnosed PASH in 13 cases out of 28 cases and vacuum-assisted biopsy correctly identified PASH in all 3 cases.

4细胞性纤维腺瘤和囊肉瘤:PASH缺乏真正的间叶细胞过生长的现象,其细胞缺乏多形性,无核分裂象,也没有纤维腺瘤或囊肉瘤的上皮成分的生长类型。

This paper presents a multigrid parallel algorithm of one dimensional virtual boundary ransack forecast, and discusses its convergence.

对网格方程组作多重网格区域分裂并行计算,虚拟边界预报提出一维搜索算法,并讨论相应的收敛性;通过 GS迭代的性质,构造区间压缩算法,证明了其收敛性。

Studies also indicated that genistein exsists not only in soybeans but also in many kinds of plants such as vegetables and fruits.As a potential anticancer agent, the actional mechanisms of genistein mainly includes as follows:First, genistein can depress the activity of protein tyrosine kinase and transduction pathways for the phosphorylation of receptors and mitosis signal. So genistein can lead to cells' proliferation depressed. Second, genistein has minimal effects of phytoestrogens. It can be combined with estrogen receptor and improve the synthesis of cellular sex hormone binding glulobin, and improve the activity of UDP-glucuronyl transferase. Through these pathways, it can inhibit the cell activity of breast cancer and prostate cancer.

作为一个很有潜力的抗肿瘤物质,三羟异黄酮的作用机制主要包括:①抑制蛋白酪氨酸激酶活性,可阻抑PTK引起的受体磷酸化和有丝分裂的信号传递,导致癌细胞增殖受抑;②弱雌激素作用:可通过与体内雌激素受体结合,并可增加细胞内性激素结合球蛋白的合成,增加UDP-葡糖醛酸转移酶的活性等途径抑制乳腺癌和前列腺癌细胞活性;③拓扑酶Ⅰ和Ⅱ抑制剂,抑制细胞活性;④上调细胞周期性负性调节因子P21WAF1/CIP1的表达,使之负性调节因子作用增强;⑤可阻止胰岛素样生长因子-Ⅰ、肝细胞生长因子和神经生长因子的作用而抑制肿瘤生长;⑥其他:抗氧化作用、抑制热休克蛋白、诱导细胞凋亡、抑制新生血管生成和抑制多种耐药相关蛋白等。

The structure, division and growth of embryogenic callus of litchi and longan were observed by paraffin method.

通过石蜡切片观察荔枝胚性愈伤组织的结构以及分裂、生长的方式,并与龙眼胚性愈伤组织作比较。

Results Myoid/myofibroblastic differentiation occurred most commonly in fibrosarcomatous DFSP. It was recognized histologically as peripherally distributed or randomly scattered small eosinophilic nodules or short bundles, which were composed of bland spindle cells, closely resembling smooth muscle cells or myofibroblasts.

结果 肌样/肌纤维母细胞性分化多出现在纤维肉瘤型DFSP中,表现为肿瘤周边部或肿瘤内散在性分布的深嗜伊红色小结节或短条束,由梭形细胞组成,细胞多无异型性,核分裂象也罕见,形态上似平滑肌细胞或肌纤维母细胞。

The results showed that the non-embryonic callus were cultured on the MS medium contained 4.0 mg · L-1 2,4-D and 0.5 mg · L-1 6-BA, embryogenic cells appeared in it. Then the single embryogenic cells formed a proembryo composed of many cells through cell division.

结果表明,非胚性愈伤组织转入到MS + 4.0 mg · L-1 2,4-D + 0.5 mg · L-1 6-BA培养基培养后,愈伤组织中先出现一些胚性细胞;然后单个胚性细胞分裂形成一个由多细胞组成的原胚。

The border of hyperplastic nodal which had no pathological nuclear mitoses, invasion and necrosis was clear. The staining of 8 antidodies had not significant value to the differential diagnosis between basal cell adenocarcinoma and adenoma of prostate.

而基底细胞腺瘤内增生的基底细胞异型性不明显,无病理性核分裂象,增生结节周界清,无浸润性边缘和坏死。8种抗体的免疫酶标记在前列腺基底细胞腺癌和腺瘤的鉴别诊断上无显著性意义。

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Lugalbanda was a god and shepherd king of Uruk where he was worshipped for over a thousand years.

Lugalbanda 是神和被崇拜了一千年多 Uruk古埃及喜克索王朝国王。

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