分泌素

Calcium sulfate has been used for bone regenation in oral medicine. Osteopontin, a marker molecule, expressed by osteoblast, plays multiple roles in human body. However, the effect of calcium sulfate on osteopontin expressed in osteoblasts is unclear. In this study, U-2 osteosarcoma osteoblastic cells were cultured in 0, 0.5, 1, or 10 μM calcium sulfate hemihydrate. There was no effect in the proliferation of cells, suggesting that calcium sulfate up to 10 μM is biocompatible. The cells and conditioned media were collected for analyzing mRNA and protein levels of osteopontin by reverse-transcription polymerase chain reaction and Western blot, respectively.

硫酸钙用於口腔医学中的骨头再生已经有多年历史，骨桥素是一种被骨母细胞分泌且在人体扮演重要多重角色的标的分子，然而，硫酸钙在骨母细胞分泌硫酸钙上的影响仍未明朗，在本实验之中，培养U-2骨肉瘤类骨母细胞(U-2 osteosarcoma osteoblastic cells)於0、0.5、1、10 μM的硫酸钙之中，在细胞数目的复制上，四种硫酸钙浓度并无影响，显示出U-2骨肉瘤类骨母细胞培养於10 μM的硫酸钙仍是生物相容性的。

The secretion of δ-hemolysin well reflects the regulation of access gene regulation system in S. aureus.

δ溶血素的分泌反映了金黄色葡萄球菌密度感应系统调控外毒素分泌的特点。

The result indicated that the percentage of lymphocyte were decreased, the percentage of neutrophile granulocytes were magnified significantly with the lighting time increasing, which was due to the level of the melatonin inhibited in the long time lighting; and to supply different exogenous dose, induce the percentage of lymphocyte were magnifying, the percentage of neutrophile granulocytes were decreased. And the statistical analysis showed there was significant difference.

结果表明：在给予不同光照时间的条件下，随着光照时间的延长，褪黑素的分泌水平受到抑制，导致具有特异免疫功能的淋巴细胞百分率下降，具有非特异免疫功能的中性粒细胞百分率上升，经统计分析表明不同组间的测定结果均存在显着差异；采用24h全天光照，用以模拟机体切除松果腺的情况，再给予一定剂量外源性褪黑素，导致机体内具有特异免疫功能的淋巴细胞百分率上升，具有非特异免疫功能的中性粒细胞百分率下降，经统计分析表明不同组间的测定结果均存在显著差异，并且高剂量褪黑素对机体的影响更为明显。

Regulation of thyroid hormone production: To prevent the overproduction or underproduction of thyroid hormones, the pituitary gland can sense how much hormone is in the blood and adjust the production of hormones accordingly.

甲状腺素生产的调节：为了防止甲状腺素的生产不足或者过剩，脑垂体可以干支血液中有多少甲状腺素从而调整甲状腺素的分泌。

Characteristics of Inclusions: After the tea is kept for a long period of time in a stall and deep fermentation processing begins, the specialties of material and manufacturing make many bioreactions occur for thorough activation of microbes to excrete extra-cellular enzymes, which impacts over 500 stuffs of tea. Theses microbes contain catechin, polyphenols, amylase, cellulose, protein, lipid ,alcohol, ketone, vitamin, microorganism, and organic acid, making them transform, isomerize and degrade, polymerize and couple, so as to produce amylase, thearubigins, theaflavins, cellulose, and microelements that other commercial teas could not produce or produce too little.

三、 内含物的特点：由于原料、制造的特别性，经长期陈化和深发酵的过程，茶叶内含物发生多种生物生化反应，充分激活微生物分泌胞外酶，作用于茶叶中的内含儿茶素、多酚、多糖、纤维素、植物素、蛋白质、脂类、醇类、酮类、维生素、微量元素、有机酸等500多种物质，使之转化、异构降解聚合耦联，生成其他商品茶无法比拟和缺乏的多糖、茶红素、茶黄素、纤维素、微量元素等，并形成以菇稀醇类为主体香气。

In order to further investigate the relationship of SP and ESCs, we design two level experiments —in vitro and in vivo. In vivo, firstly, We establish the nomal rat full-thickness wounds model, and employ integrin β1 keratin 19(K19)、 keratin 15(K15)、 Brdu as ESCs markers to conform the existence of ESCs in the granulation tissue of Group Capsaicin (rats were subcutaneously injected capsaicin pre-injury to damage sensory neuron and block the secretion of neuropeptides), Group Control, and Group SP (rats were injected SP in the wound postinjury). Secondly, as diabetic skin lacking of SP due to extensive pathological changes of sensory ending, we make a hypothesis:one of the main reason of unhealing wounds on diabetic patients could be insufficient SP which lead to fewer ESCs recruitment around wounds.

在此基础上，为进一步验证P物质促进表皮干细胞向肉芽组织中募集这一重要发现，本研究首先利用β1整合素、K19、K15等干细胞标记物以及干细胞慢周期性的特点，分别在体观察了正常皮肤伤口愈合过程中SP组、辣椒素组采用特异性感觉神经毒性药物辣椒素(capsaicin皮下预注射化学性除去感觉神经从而阻止神经肽分泌、对照组肉芽组织中表皮干细胞分布特点；其次，糖尿病患者皮肤存在周围末梢神经的损伤和神经肽含量的下降，这是否会导致糖尿病皮肤伤口创缘表皮干细胞募集不足，继发伤口难愈？

Endothelin-1 (ET-1) is a potent vasoconstrictive peptide that was isolated initially from the conditioned medium of cultured endothelial cells. It is a pathogenic mediator with a number of deleterious effects, including vasoconstriction, fibrosis, vascular hypertrophy,and inflammation.Atrial natriuretic peptide, angiotensin II and nitric oxide also takes an important role in cardiovascular system.

内皮素-1(endothelia-1，ET-1)是一种由内皮细胞合成和分泌的、具有强烈收缩血管作用和促进细胞增生的血管活性多肽，心钠素(atrialnatriuretic peptide，ANP)、血管紧张素Ⅱ(angiotensin Ⅱ，AⅡ)、NO等在心血管系统功能的调节中也起着重要作用。

Vernonia anthelmintica can significantly enhance the activity of tyrosinase in vitro and proliferation of B-16 murine melanoma cell.

结果驱虫斑鸠菊体外可激活酪氨酸酶活性，增强B - 16鼠黑素瘤细胞增殖，提高酪氨酸酶和黑色素合成能力；对整体动物黑素细胞具有促进合成和分泌作用。结论在白癜风的治疗中，驱虫斑鸠菊可增强酪氨酸酶活性，进而促进黑素合成

Compared to the respectively alone stress, cold + 5 km hypoxia (4 hours/day, continuation for 2 days) and restraint + 5 km hypoxia combinated stresses significantly inhibited body weight gain of rats, and the five stresses also markedly decreased hepatic glycogen contents, and increased plasma glucagon levels. 2. Effect of continual hypoxia on the level of insulin secretion Compared to the sea level normoxia control group, simulated continual 2 km hypoxia for 1-25 days (1, 2, 5, 10,15 and 25 days) did not significantly influence rats body weight, food intake and plasma insulin level.

连续性低氧对胰岛素分泌水平的影响与海平面常氧对照组相比，模拟2km连续低氧1-25天(1、2、5、10、15和25天)没有明显影响大鼠体重变化、摄食量和血浆胰岛素水平，但在低氧第2天显著升高肝糖原含量和血糖水平，在第10天明显升高血浆胰高血糖素水平，在第1天血浆皮质酮水平显著升高，在第1和第2天瘦素水平明显上升，然而在第5天瘦素水平显著下降。

Resells The expression of Survivin in ectopic lesion of adenomyosis group was significantly higher than that of eutopic endometrium in adenomyos

结果生存素在研究组异位病灶中广泛表达，表达的强度显著高于其在位内膜和对照组子宫内膜，增殖期高于分泌期；研究组在位内膜的生存素表达也高于对照组内膜；无论是研究组在位内膜还是对照组子宫内膜中生存素的表达均不随月经周期变化。

But we don't care about Battlegrounds.

但我们并不在乎沙场中的显露。

Ah! don't mention it, the butcher's shop is a horror.

啊！不用提了。提到肉，真是糟透了。