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Abstract] Objective For the purpose of scientific evaluation and improvement on unreasonable parameter of viral inactivation,the dynamics curve of time corresponding to effect by given viral inactivation factor treated to blood plasma product were analyzed.Methods Aimed at vesicular stomatitis virus, sindbis virus, human immunodeficiency virus, polioviruses, pseudorabies virus,encephalon-yocarditis virus; validate data of viral inactivated on pasteurization of albumin, human rabies immunoglobulin with pH 4, human immunoglobulin and human hepatitis B immunoglobulin for intravenous injection with pH 4/pasteurization,treatment on human fibrinogen and human coagulation factor Ⅷ with solvent/detergent and vapor heating at 100 ℃30 min were systemic regularized respectively.The mean and standard deviation also coefficient of variation for virus survival titer in different time were stated, dynamics curve of virus inactivation were made and analyzed.

目的 分析血液制品特定灭活因子的时效动力学曲线,科学性地评价与改进不合理的病毒灭活参方法系统性整理针对水疱性口炎病毒、黄热病毒、脊髓灰质炎病毒、伪狂犬病毒、脑心肌炎病毒、人类免疫缺陷病毒,人血白蛋白采用巴氏消毒法,狂犬病人免疫球蛋白采用低pH常温孵放法,静注人免疫球蛋白、静注人乙肝免疫球蛋白采用低pH/巴氏消毒法;人纤维蛋白原、人凝血因子Ⅷ采用有机溶剂/去污剂与干热法灭活病毒的验证资料,统计3批样品取样点的残余病毒滴度均值、标准差与变异系数,制作灭活病毒动力曲线图并进行分析。

Abstract] objective for the purpose of scientific evaluation and improvement on unreasonable parameter of viral inactivation,the dynamics curve of time corresponding to effect by given viral inactivation factor treated to blood plasma product were analyzed.methods aimed at vesicular stomatitis virus, sindbis virus, human immunodeficiency virus, polioviruses, pseudorabies virus,encephalon-yocarditis virus; validate data of viral inactivated on pasteurization of albumin, human rabies immunoglobulin with ph 4, human immunoglobulin and human hepatitis b immunoglobulin for intravenous injection with ph 4/pasteurization,treatment on human fibrinogen and human coagulation factor ⅷ with solvent/detergent and vapor heating at 100 ℃30 min were systemic regularized respectively.the mean and standard deviation also coefficient of variation for virus survival titer in different time were stated, dynamics curve of virus inactivation were made and analyzed.results human albumin pasteurization inactivated vsv and sindbis virus,hrig low ph inactivated vsv and sindbis virus,hrig low ph inactivated hiv virus,ivig low ph/pasteurization inactivated hiv virus,ivig low ph inactivated hiv virus,hbig low ph/pasteurization inactivated vsv,sindbis and polio virus.conclusion suggestion about improvement on unreasonable parameter and standard of virus inactivation is made,cultivate target virus directly from final product by appropriate cell or method to monitoring viral safety of blood plasma product is advanced.

目的 分析血液制品特定灭活因子的时效动力学曲线,科学性地评价与改进不合理的病毒灭活参数。方法系统性整理针对水疱性口炎病毒、黄热病毒、脊髓灰质炎病毒、伪狂犬病毒、脑心肌炎病毒、人类免疫缺陷病毒,人血白蛋白采用巴氏消毒法,狂犬病人免疫球蛋白采用低ph常温孵放法,静注人免疫球蛋白、静注人乙肝免疫球蛋白采用低ph/巴氏消毒法;人纤维蛋白原、人凝血因子ⅷ采用有机溶剂/去污剂与干热法灭活病毒的验证资料,统计3批样品多个取样点的残余病毒滴度均值、标准差与变异系数,制作灭活病毒动力曲线图并进行分析。结果人血白蛋白巴氏灭活vsv与sindbis病毒,hrig低ph灭活vsv和sindbis病毒,hrig低ph灭活hiv病毒,ivig低ph/巴氏灭活hiv病毒,ivig低ph灭活hiv病毒,hbig低ph/巴氏灭活vsv、sindbis与polio病毒。结论建议改进病毒灭活验证标准与不合理的灭活参数;采用终产品样品通过合适细胞或方法直接培养目标病毒来有效监测血液制品的病毒安全性。

At certain temperature and hydrogen flow rate, the weight changing of tungsten trioxide during the reduction was investigated by thermo balance, and the phase transformation analyzed by means of XRD.

在一定的温度和氢气流量条件下,用热分析天平精确测量WO3 还原反应过程中,不同时间的质量变化,并用X射线衍射分析进行物相鉴定,绘制纳米级WO3 (粒径≤ 5 0nm)的还原动力学曲线。

Tests were carried out using ±1 000 kV simulation tower in this paper, and switching impulse and lightning impulse flashover characteristic curves of typical air gap in ±1 000 kV transmission tower were obtained. These curves were compared with test results of ±500 and ±800 kV air gap, and the flashover characteristic of 750 kV AC transmission tower and square tower window were also discussed in this paper.

利用±1 000 kV模拟塔头进行试验,得到了±1 000 kV杆塔典型空气间隙的操作冲击和雷电冲击放电特性曲线,并与±500和±800 kV杆塔塔头的空气间隙研究成果进行对比分析,同时结合750 kV 交流杆塔塔头和正方形塔窗的操作冲击特性进行了讨论和分析。

The time and temperature dependence of dynamic modulus and phase angle of hot mix asphalt is analyzed,the master curve of dynamic modulus and phase angle is built using time-temperature superposition principle,the Witczak predictive equation is verified using the test results,which is helpful to provide good reference for China to use dynamic modulus as pavement design parameters.

分析了沥青混合料动态模量和相位角对温度和加载频率的依赖性,利用时间-温度置换原理建立了动态模量的通用曲线,并用动态模量实测结果对Witczak预估模型进行了验证和分析,为将动态模量作为沥青路面设计参数和混合料性能评价指标提供了有益参考。

Influences of several parameters, such as axial compression ratio, slenderness ratio, steel ratio and strength of the materials on the hysteresis behavior of the beam-columns are analyzed.

基于理论分析模型,分析了各参数,如构件轴压比、长细比、截面含钢率和材料强度等因素对圆钢管混凝土压弯构件P-△滞回关系曲线的影响。

Use 8 channels 10 A/DMAX 192 two shunt-wound means, the sample that can differ to 10 kinds at the same time undertakes an analysis, and basis beforehand the optical density value of demarcate and pH indicator plan to add up to a curve to give out analytic result.

采用8通道10位A/DMAX 192两片并联的方式,可以同时对10种不同的样品进行分析,并根据事先标定的光密度值和浓度的拟合曲线给出分析结果。

Composition of low molecular weight glutenin subunits and gliadins were investigated with thirty common wheat cultivars which are widely grown in Shangdong province. In our study we used acid polyacrylamide gel electrophoresis and SDS-polyacrylamide gel electrophoresis, analysed Sedimentation test, Protein content, Mixing time, Stability, Max-resistance to extension, Farinograph Quality Number and Extensogram area of the 30 common wheats. They have close relationship with the technology properties of noodle wheat cultivars.

本研究通过酸性聚丙烯酰胺凝胶电泳和SDS-聚丙烯酰胺凝胶电泳,分析了30个山东省种植面积较大且具有部分代表性的普通小麦品种的低分子量麦谷蛋白亚基和醇溶蛋白组成,测定了30个品种的蛋白质含量、沉淀值、面团形成时间、稳定性、粉质评价值、最大拉伸阻力和拉伸曲线面积等面粉及面团主要品质性状,分析了低分子量谷蛋白亚基和醇溶蛋白组成与面条小麦品质性状的关系。

Secondly, the nonlinear vibration of a mono-degree of freedom rotor supported by the AMBs is investigated also. With the altering of the PID controllers parameters, the typical nonlinear phenomena such as softening/hardening spring characteristic, jumps and separation of the resonance curve can be observed and analyzed.

其次,对PID控制的单自由度电磁轴承—转子系统由于力—电流/位移的非线性特性引起的非线性振动进行了分析研究,当控制器参数改变时,系统表现出软/硬弹簧特性,分析了主共振区的跳跃谐振及谐振曲线的分离现象。

No matter what the historical evolvement is analyzed or the theoretical frame is established, all have an important purpose that they serve the realistic analysis for China. Chapter five and chapter six of the dissertation base themselves upon realistic constraint of China, probing respectively the establishment of the zero-coupon bond yield curve of China, and the measurement and management of interest rate risk in commercial bank of China, by using the theoretical frame established before.

无论是分析历史演变,还是构建理论框架,都有一个重要目的,就是服务于对中国的现实分析,论文的第五章和第六章都是立足于中国的现实约束,运用前面构造的理论框架,分别探索中国的零息票债券收益率曲线的构建和中国的商业银行利率风险的度量与管理。

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And discuss some key point of integrated management system design, include hazard identification and risk assessment and risk control in the occupational health and safety management, the measure of satisfaction target of customer, the flawlessness of law system, the integration of the integrated management system and enterprise standardization system, unify lead institution and work orgnization, integreted internal audit and integrated management review.

同时,论述了一体化管理体系构建中的几个主要问题,包括职业健康安全管理中的危险源辨识、风险评价和风险控制、顾客满意度的科学监测、法律、法规体系的完善、一体化管理体系与企业标准化体系的有机结合、统一的领导机构和工作机构、一体化的内部审核和管理评审。

Deepwater Taranaki is investigated for its petroleum potential, using all available seismic data tied to shallow-water wells.

运用与浅水井相关的现有全部震波探测数据考察了深海区塔拉纳基盆地的油藏前景。

If you're huffing and puffing at any point during the run, slow down and make sure you can take deep breathes.

如果你任何时候在跑步过程中气喘如牛,降低速度并且确保你能够深呼吸。