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Results The karyote clearance of platelets purified by magnetic actitated cell soring LD and MS was (98.47±0.18)% and (98.44±0.24)% respectively.

采用流式细胞术检测分选前后血小板活化膜分子CD62P的表达情况,比较分选前后血小板活化程度差异。

From the present study, it has been demonstrated that CD44 is cleaved subsequently by MT1-MMP and Presenilins in PC-3 Cells, and in turn causes the release of the CD44ICD. CD44ICD translocates into nuclear and may regulate the tumor cells malignant phenotype via NF-κB pathway which plays a critical role in the malignant progression of prostate cancer, interruption of this pathway might contribute to the inhibition of tumor growth and invasion.

本研究表明:在PC-3细胞中CD44分子分别受MT1-MMP和Presenilin1/2的作用,最终导致CD44ICD从膜结合型CD44ΔE的水解释放并转移进核,并可能通过调控NF-κB等转录因子,影响肿瘤细胞的恶性表型。

In heathlty cells, AIF protein is normally confined to mitochondrial intermembrane space. However, after apoptosis is induced, AIF protein can be released from mitochondria and translocates into nucleus leading by its nuclear localization signal.

正常情况下,AIF蛋白定位于细胞线粒体膜间隙,当有凋亡信号刺激时,AIF分子从线粒体释放到细胞浆,再通过其核定位信号转位到细胞核中,直接引起染色体凝集和DNA的大片段(~50kb)断裂,导致细胞凋亡。

Two kinds of PE translocating peptides covering 253-358aa and 253-364aa were compared for their endosome-disruptive function, and the sFv23e-PEⅡ(253-364)-AIFΔ1-120 molecule displayed stronger cell killing activity, with the killing rate about 70% in vitro.

比较不同长度转位肽的作用效果,结果发现以具有较长PE转膜结构域片段的sFv23e-PE(253-364)-AIFΔ1-120分子的杀伤作用较强,杀伤率可达到70%左右。

Objective: To investigate the effects of α-lipoic acid on cell proliferation and expression of intercellular adhesion molecule-1(ICAM-1) induced by high glucose in rat mesangial cells.

目的:探讨α-硫辛酸对高糖诱导的大鼠系膜细胞增殖及细胞间耗黏分子1(ICAM-1)表达的影响。

Second, we discuss two materials which are cinnamoyl chloride and azobenzene. The cinnamoyl chloride can induce the photo-dimerization reaction under linear-polarized UV light. Similarly, azobenzene can induce the cis-trans photoisomerization under UV light.

第二部分采用光诱导配向的方式,将偶氮苯与PI结合,再利用偏极化紫外光曝光使其产生顺-反异构化反应,再用polarized-ATR-FTIR研究其三度空间之分子排列,做为未来显示器配向膜的参考。

The analysis also indicates that a rearrangement of atoms has occurred in the Si (001) surface and, while a majority of surface atoms form bonds and dimerize, a minority still exist as non-bonding atoms.

本论文对Si(001)2×1表面再构、低能粒子轰击对再构表面的影响以及在Si(111)表面低能沉积类金刚石膜进行了分子动力学模拟研究。

Three-dimensional computer molecular dynamics simulation for high temperature static relaxation process in the epitaxial face-centered cubic crystal aluminum films has been carried out.

运用分子动力学方法对面心立方晶体铝外延膜的高温弛豫过程进行了二维计算机模拟。

Caveolae are flask-shaped invaginations of the plasma membrane that play an important role in cellular activities, including molecule transportation, cell adhesion, and signal transduction.

Caveolae是细胞膜内陷形成的烧瓶状的特殊膜结构,参与包括细胞的分子运输、细胞粘附和信号转导在内的多种细胞活动。

With hydroxylamine hydrochloride as reducing agent mixed gold chloride acid on the surface of the second deposit silicon film growth, measured by scanning electron microscopy of the surface morphology of silicon, this new system of surface-enhanced Raman scattering activity the study of crystal violet probe molecules to study the SERS activity revealed that the system is a very efficient SERS substrate activity, and the SERS activity is better than chemically prepared gold plastic.

用盐酸羟胺作为还原剂混合氯金酸对硅片表面进行二次金膜的生长,用扫描电子显微镜测定硅片的表面形貌,对这种新体系的表面增强拉曼散射活性进行了研究,以结晶紫为探针分子,研究其SERS活性发现该体系是一种非常高效的SERS活性增强基底,并且其SERS活性优于用化学方法制备的金胶。

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