分子性

As stereochemistry in drug molecule governs its biological activity, chirality is emerging as a key issue in pharmaceutical research.

药物分子的立体化学决定了其生物活性，手性已成为药物研究的一个关键因素。

Six Pt complexes with chital 1,2 --diaminocyclohexane as carrier ligand were synthesized, their compositions and strctures were characterized by elemental analysis,IR spectroscopy and molecular modeling.

合成了六种以不同手性的1，2-环己二胺(1，2-dach)作为载体配体的铂配合物，用元素分析、红外及分子图形方法对其组成和结构进行了表征。

The valence electron structure of medium chrome cast iron matrix is set up and the effect of Si on medium-temperature phase transformation is analyzed by using empirical electron theory of solids and molecules.

此文建立了290Cr8Si2中铬铸铁基体的价电子结构，运用固体与分子经验电子理论分析了中铬铸铁中Si对铸铁中温相变的影响，分析和实验结果表明，290Cr8Si2中铬铸铁基体含C、Cr、Si的-γFe晶胞中，C原子与Si原子的结合力强于C原子与Cr原子的结合力，中铬铸铁中较高的含Si量降低了铸铁基体的含Cr量，进而降低了中铬铸铁的淬透性。

Results Eleven proteins, including chymotrypsinogen B1 precursor, carboxypeptidase A1, trypsinogen 2, chymotryptic peptide C, trypsin 1, carboxypeptidase B1, kinesin superfamily proteins 3B, trypsin 2, mitochondria protein gene, elastase 3A and colipase were found to be able to bind to HCV core protein. Conclusions Proteins related with metabolism of glucose and lipid may bind to HCV core protein.

因此我们应用酵母双杂交技术筛选人胰腺细胞 cDNA 文库中的 HCV 核心蛋白结合蛋白基因，为研究 HCV 慢性感染与胰岛素抵抗（ insulin resistance ， IR ）、代谢性疾病之间的相关性及其作用机制，以及进一步研究 HCV 影响糖、脂类代谢的分子生物学机制提供一定的思路和方向。

In the early 1990s, knowing that the constitutively activated kinase had a major role in CML, Druker approached scientists at what was then Ciba-Geigy with a proposal to find a small molecule that would inhibit the BCR-ABL tyrosine kinase activity.

在90年代早期，Druker认识到组成性活化的激酶在CML中的重要作用，并向当时的汽巴-嘉基药厂的科学家们提议寻找一种可抑制BCR-ABL酪氨酸激酶活性的小分子物质。

The Pt/FDU-14 catalysts can be effectively applied in the asymmetric hydrogenation of ethyl pyruvate after chirally modified with cinchonidine.

考察了经过手性分子辛可尼定修饰后的Pt/FDU-14催化剂在丙酮酸乙酯不对称氢化反应中的催化性能。

A new chiral quaternary ammonium salt 1a was synthesized by the reaction of cinchonine and(2,4,6-)trimethyl benzyl chloride.Etherification between 1a and benzyl bromide,allyl chloride,or methyl give corresponding etherified quaternary ammonium salts 1b,1c,and 1d.

由辛可宁和2，4，6-三甲基苄氯，合成了一种新的手性季铵盐(1a)，并进一步用苄基溴、碘甲烷和烯丙基氯对分子中的羟基进行醚化，得到相转移催化剂1b、1c和1d。

Vibrational circular dichroism is a useful technology to measure the circular dichroism of chiral molecules in the IR region, which remarkably expands the application of circular dichroism to the determination of AC.

振动圆二色谱是在红外波长区域测定分子圆二色性的一种新方法，极大地扩展了圆二色谱的应用范围。

Typical bands were used to analyze relation with ecotypes and characters of fruits, indicating that there was no relation between typical bands and ecotypes, but some extent relation between bands and characters of fruits existed. If all cultivars were divided into freestone and clingstone, melting and nonmelting, both freestone (ratio shared total survey, 41/56=73.2%) and clingstone (ratio shared total survey, 33/79=41.8%) appeared in the loci of S_(167)-1050 bp linked marker raised by Warburton et al. It was apparently not strong linkage between the marker and the character, and exchange rate of genes was high. If combinations of S_(167)-850bp and S_(167)-1050bp or S_(167)-850bp and S_(167)-1400bp were used to distinguish characters of fruits, 6 freestone accessions without clingstone ones and 6 melting accessions without nonmelting ones displayed in the first combination of markers, 20 clingstone accessions and 2 semi-freestone ones without freestone ones appeared in the second combination of markers.

通过典型带对不同生态型、果实性状为类别进行分析，结果未发现有与生态型相吻合的特征带出现，而将供试所有品种按离核、粘核和溶质、不溶质划分归类，供试品种在Warburton等得到S_(167)-1050 bp处粘离核分子标记，出现既有离核(占供试离核41／56=73.2％)，又有粘核(占供试粘核33／79=41.8％)，可见此连锁标记连锁性不强，发生交换的机率较高，而S_(167)-850bp带和S_(167)-1050bp带同时出现时，该组包含6个离核，无粘核品种；6个溶质，而无不溶质。S_(167)-850bp和S_(167)-1400bp同时出现时，包含20个粘核品种和2个半离核品种。

Simple sequence repeats molecular markers are useful for a variety of applications in plant genetics and breeding because of their reproducibility, multiallelic nature, codominant inheritance, relative abundance and good genome coverage.

简单重复序列(simple sequence repeat， SSR)分子标记因其具有稳定性好、多等位基因、共显性遗传、数量丰富、基因组覆盖性好等优点，现已广泛应用于多种植物的遗传育种研究中。

The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了，排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意，我建议我们在价格上大家各让一半。