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Vascular hyperpermeability is one of the important causein hypovole-mia and organs disfunction after various kinds of shock,and its treatment is still one of the problems in the medical field. For example,the operative methods of preventing hyperpermeability and plasm bleeding is still unreliable after severity burn,and traditional treatment just passively transfuses according to the burn clysis formula instead of inhibiting permeability by injecting drugs. The principal reason is that pathogenesis of vascular endothelial cell permeabilty has not been entirely revealed at the level of molecular biology.

血管通透性增高是休克时有效血容量减少和器官功能损害的重要原因之一,它的防治一直是医学界的一个难题,如在大面积烧伤时,至今未能找到一个简单有效的防治血管通透性升高和血浆渗出丢失的方法,传统的方法只是根据烧伤补液公式测算进行被动的补液来纠正,而不能依靠注射化学制剂来终止其渗出,主要原因是未能从分子生物学水平揭示血管内皮细胞渗出的机制。

This paper deals with different ways to depolymerize the chitosan into water soluble low molecular weight polymer.Molecular weight of water soluble low molecular weight chitosan was determinated by GFC.

探讨并比较了壳聚糖解聚成水溶性低聚物的不同途径,用GFC方法测定了水溶性低聚物的相对分子质量,证实选用NaNO2作解聚剂解聚效果良好。

Studing on samarium diiodide promoted asymmetric intramolecular reducing coupling reactions, we have made the resolution of the racemic biaryl dials by using enantiomeric N-tert-butanesulfinamine as the resolving reagent successfully and thus obtained a series of axially chiral biaryl dials with high enantiomeric excess.

中文摘要在二碘化钐促进的分子内不对称还原偶联反应中,我们不仅对联芳基二醛底物的合成路线进行了优化,还发现N-叔丁基亚磺酰胺辅基可以作为手性试剂,成功地对联芳基骨架二醛化合物进行拆分,得到高对映体过量的轴手性二醛类化合物。

And molecular genetic analysis was performed on DNA extracted from the twins Ⅳ-3 and Ⅳ-4 to identify whether they are monozygotic twins or dizygotic twins Results The family history was consistent with a maternal inheritance and the proband exhibited a typical clinical feature of LHON.

最后应用分子遗传学技术对该家系中的一对双生子(其中一人为先证者,另一个未患病)进行DNA多态性的比较分析以鉴定其卵性。

ECP 63 might be a useful molecular marker for identifying embryogenic cells and non-embryogenic cells.

ECP63 cDNA可作为识别胡萝卜胚性细胞和非胚性细胞的一个分子标记。

Homology modeling of 3-D structure of two AChE from L.entomophila were constructed using H.sapiens(1p0i:A) native BuChE structure and Drosophila melanogaster(1d×4:A) native AChE structure as templates,respectively,by SWISS-MODEL.The catalytic triad were found and denoted in the 3-D structure of AChE from L. entomophila referring to T.californica.2.2 Gene cloning ofβ-actin and mRNA expression levels of two AChE genes from L. entomophilaBecause no reference gene has ever been used in Real Time PCR for L.entomophila in GeneBank,a fragment ofβ-actin gene was cloned from L.entomophila(GenBank Accession No.: FJ041117).It consists of 822 bp encoding a protein of 273 amino acids residues.

利用蛋白质结构同源建模工具,分别以人丁酰胆碱酯酶(1p0i:A)和果蝇乙酰胆碱酯酶(1d×4:A)的蛋白晶体结构为模板,对嗜虫书虱2个AChE的三维结构进行同源建模,并在三维结构中发现了AChE的酶解活性位点,证明嗜虫书虱体内也存在2个AChE基因。2.2嗜虫书虱β-actin基因克隆及乙酰胆碱酯酶基因mRNA表达水平研究目前关于嗜虫书虱的分子生物学研究较少,在GenBank中没有可用作内参基因的序列,因此本研究从嗜虫书虱体内克隆获得β—actin基因片段(GenBank登录号:FJ041117),该片段长度为822 bp,编码273个氨基酸残基,同源性比对分析表明该片段与其它昆虫的β—actin基因具有很高的同源性。

Methhods:1:The chemical components of Chinese herbal medicines extracted with petroleum ether,chloroform, ethyl acetate,ethenol and water respectively were analyzed and compared.2.The specimens were analyzed with ultraviolet-visible absorption spectrophotometry.

(1)按中药多分子体系的脂溶性差异,分为石油醚、氯仿、乙酸乙脂、乙醇和水的溶出性成分集合,然后进行&对药&与非&对药&的对比分析;(2)用紫外-可见光光度计测定吸收光谱曲线。

The molecular mechanism in hypertensive kidney lesion was demonstrated by monitoring the levels of serum TGF-β, nitric oxide and plasma AngH in essential hypertensive patients and investigating the effect of information convection in endothelial cell on fibrillar collagen metabolism and its relationship with hypertensive kidney lesion.

该课题通过测定原发性高血压病人及伴肾脏损害病人的TGF-β_1、NO和Ang Ⅱ的水平,探讨内皮细胞产生的信息传递对纤维胶原代谢的影响及与高血压性肾损害的关系,以揭示高血压性肾损害发生发展的细胞分子机制。

2N gametes are the result of meiotic mutation during micro- and mega-sporogenesis that bear the sporophytic rather than the gametophytic chromosome number. This paper reviewed the genetic markers including the morphologic, cytological, isozymes and DNA markers, which have been employed in the generation, inheritance, heterozygosity and marker-assisted breeding of 2n gametes based on the frequency of large pollen grains, cytological analyses, unexpected occurrence of polyploidy progeny and the associations between parents and progenies.

文章综述了植物2n配子发生及其遗传标记研究现状,论述涉及有关形态学标记、细胞学标记、同工酶标记乃至DNA标记等遗传标记在2n配子研究中的应用,指出通过花粉形态观察、大小孢子母细胞减数分裂行为观察、杂种后代倍性鉴定以及亲子分子标记相关分析等,对2n配子发生、2n配子遗传类型与杂合性以及2n配子在育种实践中的有效性等进行研究。

In the current study, we have detected the mtDNA mutation in lung cancer, investigated the correlation between the mtDNA mutations and carcinogenesis, and explored the possibility of mtDNA mutations as a biomarker. We also analyzed the reasons for the homoplasmic mutations of mtDNA.

为了探讨mtDNA突变在肺癌发生中的意义、mtDNA突变在肺癌早期诊断中作为分子标记的可能性以及mtDNA多态性与肺癌易感性的关系,我们检测了肺癌mtDNA突变,分析了肿瘤中mtDNA同质性突变的形成原因。

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The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了,排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意,我建议我们在价格上大家各让一半。

After an hour and no pup, look for continued contractions and arching of the back with no pup as a sign of trouble.

一个小时后,并没有任何的PUP ,寻找继续收缩和拱的背面没有任何的PUP作为一个注册的麻烦。