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Common strategies and examples of protein engineering in improving protein solubility, homogeneity, and crystallizability are presented.

近年来分子生物学尤其是蛋白质工程的应用有效地提高蛋白质的溶解度、均一性及可结晶性等内在特性,促进蛋白质的结晶,成为提高蛋白质结晶能力和蛋白质晶体分辨率的有效途径。

In all 22 loci detected, 18 and 11 loci are polymorphic between and within cultivar, respectively.

所使用的SSR分子标记共可侦测到21个基因座,其中有18个基因座在品种间表现多型性,有11个基因座在品种内表现多型性。

Truncation mutations in the adenomatous polyposis coli protein are responsible for familial and sporadic colonic tumours. Except for its function as a role in regulating b-catenin, recent studies show that APC has additional roles in cytoskeletal regulation. It binds to microactin and microtubules directly and indirectly. Furthermore, APC plays an important role in mediating the detraction of chromosome.

编码APC蛋白(adenomatous polyposis coli, APC)基因的缺失突变会导致家族性和散发性的结肠癌,APC蛋白除了能直接参与Wnt信号途径调节b-catenin的浓度之外,最近的研究表明APC蛋白能够与细胞骨架的主要成分微管和微丝直接或间接结合,通过调节微管的解聚和聚合,间接调节染色体的分离,作为潜在的细胞骨架调节分子将细胞骨架与重要的细胞信号转导通路紧密联系在一起。

Electronegativity is defined as the ability of an atom in a molecule to attract electrons to itself.

电负性是元素的原子在分子中吸引电子的能力。1932年Pauling首先提出了电负性的概念。

In the framework of density functional theory, the development of electronegativity, electronegativity equalization theory and their applications for exploring some molecular properties are overviewed.

文摘:以密度泛函理论为框架,综述电负性和电负性均衡理论的发展及其在探讨各种分子性质时的应用。

Results indicate that if the carbon doublebond and carbonylcompounds were added into the surfactant molecule,the emulsification properties such as emulsifiability foaming property and foam stability will improve a lot.

实验分析表明,在表面活性剂分子中加入双键和羰基,会使得由此制得的乳化剂的乳化力、起泡性与稳泡性等性能都有良好的改善。

The brain capillary and star glue quality cell which enwrap around it under thenormal condition form the permeation extremely low blood-brain barrier, onlypermit some little molecule to pass; When cerebral isc.

正常状态下的脑毛细血管及包裹在其周围的星形胶质细胞构成了通透性极低的血脑屏障,只允许一些小分子物质通过;当缺血性中风发生时,微血管通透性发生显著改变,这种病理变化与脑内皮细胞损伤导致的功能变化有直接的关联。

To examinate the thermal properties by TGA、DSC and figure out the maximum decompose temperature which survey the range of liquid crystal temperature. We synthesize conjugated polymer successfully and these emitted blue fluorescence. Hope this experiments will supply well-contribution in field of organic light-emitting diodes.

以TGA、DSC测定其热性质,并了解到由TGA的5%热重损失温度再进行测出液晶温度范围,我们成功的合成出具有良好的加工性的共轭性分子,发光性质都出现在蓝光领域,愿在有机发光二极体的领域上有重大的贡献。

objective: to observe the curative effect and safety of tia treated with low molecular weight heparin.

目的:观察低分子肝素对频发性短暂性脑缺血发作的疗效与安全性。

Research background: Choroidal neovascularization is a common cause of vision loss in patients, which often resulted from exudative Age-related macular degeneration、 pathologic myopia、 central serous chorioretinopathy、ocular histoplasmosis and angioid streaks, Rarely, CNV is seen in children, usually in association with inherited macular dystrophies. Despite extensive basic and clinical research, our knowledge of the complicated molecular mechanism of CNV is still limited, for these reasons currently used therapeutic approaches are insufficiently effective.

课题研究背景:脉络膜新生血管(choroidal neovascularization,CNV)是导致视力丧失的一种常见原因,多继发于渗出型年龄相关性黄斑变性、近视性黄斑变性、中心性浆液性脉络膜视网膜炎、眼组织胞浆菌病和眼底血管样条纹等眼病,在儿童罕见,主要与遗传性黄斑营养不良有关,尽管近年来进行了大量的基础和临床研究,但对CNV复杂分子机制的认识仍然非常有限,因此目前的治疗措施都不尽如人意。

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The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了,排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意,我建议我们在价格上大家各让一半。

After an hour and no pup, look for continued contractions and arching of the back with no pup as a sign of trouble.

一个小时后,并没有任何的PUP ,寻找继续收缩和拱的背面没有任何的PUP作为一个注册的麻烦。