分子内的

A large number of bond-type complexes, as long as the hydrogen of the molecules covalently coupled to the molecular approach in an electronegative atom up, that constitutes a hydrogen bond, there are intramolecular hydrogen bonds and intermolecular hydrogen bonds of the points, will affect the formation of complex reaction carried out, such as in solution adding dioxa cyclohexane, or tetrahydrofuran, will reduce the alkylation reaction rate.

氢键型络合物为数众多，只要含氢的分子以共价键方式耦合到分子中一个电负性原子上去，即构成氢键，有分子内氢键和分子间氢键之分，络合物的形成将会影响反应的进行，如在溶液中加入二氧杂环己烷或四氢呋喃，都会降低烷基化反应速率。

The interaction between three small flavoind drug molecules, which are apigenin, galangin and genistein, and BSA is investigated with fluorescence spectroscopy using the drug's quenching on the endogenous fluorescence of serum albumin.

采用荧光光谱法，利用药物对牛血清白蛋白自身内源荧光的猝灭，研究了芹菜素、高良姜素和染料木素这三种黄酮药物小分子与牛血清白蛋白分子间的相互作用，研究发现药物分子与牛血清白蛋白分子之间发生了有效的静态猝灭。。。

In addition, the influences of forming IHB between hydroxyls at position 1,2 on photosensitivity of HYP were investigated as well.

HYP分子内氢传递产生的异构体在能量上不稳定，进而在基础上探讨了1，2位OH分子内氢键的形成对HYP光敏活性的影响。

To an asymmetric synthesis of (1), we applied a type of Roush addition in the first step to introduce the C4 stereocenter, and then the chair substance -122 are readily transformed into the title compound -aphanorphine using the same route as to the racemic target molecular.

aphanorphine分子的不对称合成是在第一步通过对甲氧基苯乙醛（119）发生Roush反应引入手性，得到手性高烯丙醇-122，然后利用与合成外消旋目标分子相同的方法，光学纯化合物-122经一系列转化可得到光学纯中间体化合物139；化合物139发生分子内傅—克反应的过程中，由C4位手性立体特异地控制C1位手性的生成，从而解决-aphanorphine分子中的手性问题。

The Xray diffraction analysis of the compounds (3) and (4) shows the presence of an intramolecular coordination of oxygen to the tin atom giving rise to a fivemembered ring in which the metal exhibits a distorted trigonal bipyramidal geometry.

并通过X-射线衍射测定了（3）和（4）的晶体结构，其空间群均为P2〓/c，晶胞内分子数Z=4，分子结构是以锡原子为中心金属原子、含分子内O→Sn配位键五员环的扭曲三角双锥结构，碳碳双键的两个氢是顺式构型。

Many multi chromophoric organic dyes with covalent linkage between the chromophores, one of which can act as a triplet acceptor of the excess energy, have been synthesized and studied.

本文综述近几年多发色团染料分子内能量传递领域的研究概况，重点介绍了分子内能量传递对组装型多发色团有机染料光稳定性影响的研究进展。

By the partial purification of Arthrobacter nicotinovorus D-97 endocellular enzymes and the results of enzymatic reaction of enzymes of partition collection, it was found that enzymes related to trehalose synthesis were consisted of Trehalose-forming Enzyme and Trehalose-releasing Enzyme . Trehalose-forming Enzyme could convert maltooligosaccharides into non-reducing maltooligosyl trehalose by intramolecular transglycosylation, and Trehalose-releasing Enzyme could hydrolyze α-1, 4 linkage between the trehalose residue and the maltooligosaccharide residue to release trehalose and maltooligosaccharides with two glucose monomer lesser.

将食尼古丁节杆菌D-97胞内酶部分纯化并对各收集组分进行酶反应，发现其海藻糖合成酶系由海藻糖生成酶(Trehalose-forming Enzyme，TFE)和海藻糖释放酶(Trehalose-releasingEnzyme，TRE)组成，前者分子内转糖基将直链麦芽寡糖转化为没有还原性的麦芽寡糖基海藻糖，后者专一切割麦芽寡糖基海藻糖分子上麦芽寡糖基与海藻糖连接的α-1，4糖苷键，从而释放出海藻糖和减少了两个葡萄糖单体的麦芽寡糖。

The fluorescence spectra of 4- 5 '-p-biphenylyloxadiazolyl-2' benzyl ω-p-biphenylyl polymethylene car-boxylate have been determined. The results of experi-ment show that they can form not only intramolecularexciplex but also intermolecular excimer and triplex.

测定了ω-对联苯基多亚甲基羧酸4-[5'-对联苯基〓二唑-2']苄酯的荧光发射光谱，从实验结果得到，它们不但可以形成分子内激基复合物，而且可以形成分子间激基缔合物和三分子激基复合物。

It is valuable to discover the function of signal molecules with investigations ontheir expression and localisation in oocytes.

研究信号分子在卵母细胞内的表达与定位对于阐明这些分子在卵内的功能具有重要作用。

The results of its intrinsic fluorescence spectroscopy and fluorescence phase diagram showed that when the guanidine hydrochloride concentration in denaturation solution was about 1.0 mol/L, there existed a partially folded intermediate of Bacillus amyloliquefaciens a-amylase during its unfolding procedure, which followed a three-state model; the result of its fluorescence probe showed that when the guanidine hydrochloride concentration in denaturation solution was about 1.0 mol/L, there existed some stable hydrophobic regions, which could interact with a hydrophobic reagent 8-anilino-1-naphthalene sulfonic acid, in the partially folded intermediate of Bacillus amyloliquefaciens a-amylase; and the results of fluorescence quenching using acrylamide and potassium iodide as quenchers showed the distribution of Trp residues in Bacillus amyloliquefaciens a-amylase in different denaturation solution, with the maximum number (8) of tryptophan residues in a partially folded intermediate Bacillus amyloliquefaciens a-amylase molecule could be quenched by potassium iodide; and the results of their protein electrophoresis and SEC showed that no aggregate or aggregate precipitation of Bacillus amyloliquefaciens a-amylase formed during the whole unfolding procedure of Bacillus amyloliquefaciens a-amylase induced by guanidine hydrochloride.

内源荧光光谱和荧光相图结果表明，当变性液中盐酸胍浓度约为1.0 mol/L时，芽孢杆菌a-淀粉酶的去折叠过程中出现一个部分折叠中间体，其去折叠过程符合&三态模型&；荧光探针结果表明，在溶液中盐酸胍浓度约为1.0 mol/L时，中间态芽孢杆菌a-淀粉酶分子中存在着能够与探针分子1-苯胺基-8-萘磺酸结合的稳定的疏水区域；荧光猝灭研究给出了不同程度变性的淀粉液化芽孢杆菌a-淀粉酶中的Trp的分布情况，结果表明中间态芽孢杆菌a-淀粉酶分子中能够被碘化钾猝灭的位于分子表面的色氨酸残基数目达到最大的8个；蛋白电泳和体积排阻色谱结果表明，在盐酸胍诱导的芽孢杆菌a-淀粉酶分子的整个去折叠过程中，不会以共价键或非共价键形式形成芽孢杆菌a-淀粉酶分子之间的集聚体或集聚体沉淀。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。