出血后的

60Mm anterior and 1. 20mm lateral to bregma and 4. 00mm ventral to the cortical surface . 2 days later, ICH was induced by the standard method. At 7d, animals were sacrificed to investigate distribution of EGFP-expressing or BrdU-labeled cells around hemotoma.

根据以上实验结果，在分离、培养、传代获得NSC的基础上，采用pEGFP转染或BrdU标记体外培养NSC后，将细胞移植入前囟前1.60mm，矢状缝向右1.20mm，深4.00mm的细胞增生活跃的前脑脑室下区。2d后诱导脑出血模型，出血后7d处死动物检测EGFP或BrdU阳性细胞在血肿周围的分布情况。

The incidence of early epileptic seizures after intracerebral hemorrhage was high. The cortical hemorrhage and the medical history of intracerebral hemorrhage, electrolyte disbalance were the important related factors for the incidence of early epileptic seizures after intracerebral hemorrhage. The cortical hemorrhage was the independent risk factor.

脑出血后早发性癫痫发作的发生率较高，皮质出血、脑出血史以及电解质紊乱是影响脑出血后早发性癫痫发作的重要因素，皮质出血为独立的危险因素。

Univariate analysis revealed that a high incidence of early epileptic seizures after intracerebral hemorrhage ocurred in patients with cortical hemorrhage, the medical history of intracerebral hemorrhage, electrolyte disbalance. Logistic regression analysis revealed that the position of hemorrhage and times of hemorrhage and electrolytic states were positively correlated with the incidence of early epileptic seizures after intracerebral hemorrhage. The cortical hemorrhage was the independent risk factor for the early epileptic seizures after intracerebral hemorrhage.

单因素分析显示，皮质出血、再发脑出血、电解质紊乱者易发生脑出血后早发性癫痫发作；Logistic回归分析显示，出血部位、出血次数和电解质情况与脑出血后早发性癫痫发作的发生有关，其中皮质出血为与脑出血后早发性癫痫发作有关的独立危险因素。

And There was no serious complication;②In the course ofinterventional therapy, Direct portal vein angiography demonstrated vena coronaria ventriculi(100%)andgastricveins(65.26%)andvenagastricaposterior38.43%, Angiography demonstrated venacoronariaventriculi communicate esophagus varicose veins, gastric veins and vena gastrica posterior communicategastric varicose veins. vena coronaria ventriculi had only a small percentage of double vein, about30.57%. The sites of vena coronaria ventriculi arising from the portal vein, splenic vein, portosplenic junction, were found in 52.06%、27.39%、20.55% respectively.③12 extrahepaticprotosystemic shunts were found in these patients. Include gastro-nephrosshuntof 3 cases, 7 caseswere splenetic- nephros shunt and 2 cases shown recanalization of umbilical vein .④The averageportal pressure before and after the procedure were 3.87±1.82kPa and 3.64±1.14kPa in 73patients, but to the time of rebleeding, it was 3.96±0.23kPa in the 11 cases.⑤There werethree kinds of variceal outcome: disappearance (54,low degree (19).⑥Spearman logisticanalyse and ANOVAtest shown liver function class, variceal degree of the splenic necrosis area,the blood direction in portal vein before operation and remain small collateral routes were thesignificant factors concerning outcome of varices.⑦The bleeding volume and portalhypertensive gastropathy are main risk factors of rebleeding.⑧The course of livercirrhosis is the risk factor of survival and extrahepatic portosystemic shunt , fine varices are thebeneficial factors to survival.⑨During all cases'followed-up data, the 1, 2, 3, 4, 5 yearcumulative survival rates and rebleeding rates were 17.81%, 28.77%, 38.36%, 43.84%, 47.95%and93.15%,91.78%,86.30%,83.56%,80.82%respectively. Conclusion The interventional disconnection treatment for liver cirrhosis and portalhypertension was designed suitability. It rapidlycontrol bleeding,butpressure of portal vein was notobvious high, perfusion was not low .it was compared with surgery therapeutic that interventionaldisconnection treatment was safe and had a significant clinical effect to hemorrhage and preventfrom rebleeding.

结果：①术后一过性发热62例(84.9%)，腹痛腹胀48例(65.8%)是介入断流术常见的并发症，未发生严重并发症；②门静脉造影显示胃冠状静脉、胃短静脉和胃后静脉的曲张分流的出现率是100%、65.26%和38.34%；显示食管静脉曲张主要由胃冠状静脉供血，胃静脉曲张主要由胃短静脉和胃后静脉供血；胃冠状静脉大多数为单支，少数为双支，其双支的出现率分别为30.57%；胃冠状静脉开口于门静脉主干的为52.06%，开口于脾静脉主干的为27.39%和开口于门脾静脉交汇处的为20.55%；③发现胃肾分流3例，脾肾分流7例、腹膜后门腔静脉分流2例，以及CTA检查发现脐静脉开放者2例；④73例患者介入断流术前和术后平均自由门静脉压力分别为3.87±1.82kpa和3.64±1.14kpa，前后比较存在显著性差异；11例再次介入手术患者的术前、术后和复发后的自由门静脉压力分别为4.02±0.24kpa、3.82±0.25kpa和3.93±0.23kpa ，前后比较发现首次术前与术后存在显著性差异，首次术前和复发出血术前门静脉压力比较无显著性差异；⑤介入术后复查曲张静脉转归基本消失54例，轻度19例；⑥Spearman相关分析和Logistic多因素回归分析，肝功能分级、静脉曲张程度、门脉血流方向和残存小侧支四个因素对曲张静脉转归有影响；Spearman相关分析和Logistic多因素回归分析门脉高压性胃病和出血量等因素对复发出血时间有影响；⑦COX回归分析，门体分流和曲张静脉转归两个因素对术后生存有影响；⑧术后随访6-70月，1、2、3、4、5年的累计复发出血率和累计生存率分别为17.81%、28.77%、38.36%、43.84%、47.95%和93.15%、91.78%、86.30%、83.56%、80.82%；结论：介入断流术治疗门脉高压食管胃底静脉曲张有独特的优点，可以快速直接控制曲张静脉出血而门静脉压力无显著增高，保证了肝脏灌注；与外科分流术相比适应证广、损伤轻、术后恢复快，不易遗漏曲张静脉；肝功能分级、曲张静脉程度、门脉血流方向和残存侧支血管对食管胃曲张静脉转归有影响；门脉高压性胃病对复发出血时间有影响；门体分流和曲张静脉转归对生存时间有影响。

ObjectiveNon-heparinized autohemic arterial blood of the rat was injected into its caudate nucleus to establish a model of intracerebral hemorrhage. The changes of edema in various regions of the brain were measured at different time after hemorrhage. Meanwhile, the effects of erythrocytes and thrombin on the formation of cerebral edema after cerebral hemorrhage were studied to explore the pathophysiological mechanism of cerebral edema and the roles of erythrocytes and thrombin in this process.

目的 利用自体未肝素化新鲜血回注法建立大鼠尾状核出血模型，观察脑出血后不同时间不同部位脑组织水分含量的变化，并分别研究红细胞、凝血酶对脑出血后脑水肿形成的影响，揭示脑出血后脑水肿形成的病理生理机制，并阐明红细胞、凝血酶在脑出血后脑水肿形成中的作用，从而为临床脑出血病人病情评估及治疗提供理论依据。

Results 42 of 45 patients had a history of subarachnoid hemorrhage for 1 to 3 times. 23 and 22 cases died separately before and after digital substract angiography. 5 cases of rebleeding was relating to angiography, 24 cases died during the "high risk" period (4 to 10 days after first rupture). Rebleeding accounted for a 7.2% mortality of aneurysms preoperatively in our study. Among them, 71% was attributable directly to rebleeding, whereas 29% to non-neurological complications.

结果 45例病人中42例既往有1～3次蛛网膜下腔出血病史，住院后于数字减影脑血管造影前出血死亡者23例，造影后出血死亡者22例，其中5例出血与脑血管造影有关，24例再出血发生在动脉瘤自然出血高峰期内(4～10天)，住院期间出血死亡的发生率占我院同期动脉瘤总数的7.2%，直接死于再出血的为71%，死于非神经系统并发症的为29%。

Objective To discuss the methods and effects of the treatment under endoscope and the courses of massive hemorrhage of upper digestive tract after gastrectomy and esophagectomy.Methods Emergency endoscope ex-amination were carried out in20massive hemorrhage clients after gastrectomy and esophagectomy,after exposed and washed the bleeding part by cold0.9%NS,1∶10000adrenaline and hypertonic saline were injected in perifocal sub-mucosa.After stop bleeding and before move back the endoscope,spray some YunNanBaiYao and thrombase in the bleeding part to prevent secondary hemoorahge.

目的 探讨食管、胃切除术后上消化道出血的原因及内镜下治疗的方法、效果方法对食管、胃切除术后引起大出血的患者行急症内镜检查，用冰冻生理盐水100ml+去甲肾上腺素8mg反复冲洗，暴露出血部位后在病灶周围黏膜下注射1∶10000肾上腺素及高渗盐水，无出血后，退镜于出血部位喷洒云南白药及凝血酶，防止再次出血。

Methods Emergency endoscope ex-amination were carried out in20massive hemorrhage clients after gastrectomy and esophagectomy,after exposed and washed the bleeding part by cold0.9%NS,1∶10000adrenaline and hypertonic saline were injected in perifocal sub-mucosa.After stop bleeding and before move back the endoscope,spray some YunNanBaiYao and thrombase in the bleeding part to prevent secondary hemoorahge.

对食管、胃切除术后引起大出血的患者行急症内镜检查，用冰冻生理盐水100ml+去甲肾上腺素8mg反复冲洗，暴露出血部位后在病灶周围黏膜下注射1∶10000肾上腺素及高渗盐水，无出血后，退镜前于出血部位喷洒云南白药及凝血酶，防止再次出血。

Methods Emergency endoscope examination were carried out in 20 massive hemorrhage clients after gastrectomy and esophagectomy, after exposed and washed the bleeding part by cold 0.9% NS, 1:10000 adrenaline and hypertonic saline were injected in perifocal sub mucosa. After stop bleeding and before move back the endoscope, spray some YunNanBaiYao and thrombase in the bleeding part to prevent secondary hemoorahge.

对食管、胃切除术后引起大出血的患者行急症内镜检查，用冰冻生理盐水lOOml＋去甲肾上腺素8mg反复冲洗，暴露出血部位后在病灶周围黏膜下注射1：10000肾上腺素及高渗盐水，无出血后，退镜前于出血部位喷洒云南白药及凝血酶，防止再次出血。

NEW YORK Mar 11 - An infusion of milrinone, a phosphodiesterase inhibitor that combines vasodilating and inotropic properties, reverses the cerebral vasospasm that can accompany an aneurysmal subarachnoid hemorrhage, French researchers report in the March issue of Stroke.

法国研究者在三月《中风》期刊上报道了他们的新发现：米力农（一种磷酸二酯酶抑制剂，具有舒张血管和影响肌肉收缩力的特性）能逆转动脉瘤致蛛网膜下腔出血后的脑动脉痉挛。

Fancy gold-plated dangling earrings with facetted White Opal crystals.

花式镀金悬垂耳环与facetted白欧泊水晶。

This essay chooses the study aim from biology teachers in middle school in Shi Jiazhuang which tells us that most of the middle school biology teachers in Shi Jiazhuang have the"burnout", lower successfulness, individualize.

本文选取石家庄市初中生物教师作为研究对象，运用问卷调查的方法对石家庄市初中生物教师职业倦怠的现状进行调查，调查结果发现，石家庄市初中生物教师这一群体普遍存在职业倦怠，情感枯竭程度偏高，成就感偏低，去个性化程度最为严重。