凝血的

Defibrination of TLP1 or TLP2 is strong, but hemocoagulation of TLP4 and TLP3 is strong in vivo.

经动物体内试验表明，TLP_1、TLP_2具有较强的去纤抗凝作用，TLP_3、TLP_4不显示抗凝作用，而显示出较强的促凝血作用。

As the body response for the trauma, the adipose tissues as blood serum behavior in the wounded tissue were suffered mobilization. At the same time, the ectogenesis fat tissue entranced blood circulation. As the result of hemodynamics alteration, there were blood platelet and erythrocyte and leucocytes and lipid granules collecting on the surface of these lipid droplets. The volumes of these lipid droplets were enlargement. These lipid droplets were changed to fat embolus by the promotion of coagulation and fibrin deposition intra-blood vessel.

现代医学理论认为，外伤后组织存留的血清状态的脂肪组织受到动员，同时，损伤部位的血管外源性脂肪进入血循环，而创伤引起的机体反应使血液动力学发生改变，血小板、红细胞、白细胞及血脂乳化不稳定所析出的脂质颗粒等，均可聚集于以上脂滴的表面，使之体积增大，加之组织凝血活化酶的释放，促使血管内凝血，纤维蛋白沉积的发生，从而形成脂肪栓子，导致脂肪栓塞。

Objective: To study the effect of different anticoagulative measures during continue blood purification on the patients with disseminated intravascular coagulation and analyze influencing factors on prognosis.

目的：研究弥散性血管内凝血患者行连续性血液净化治疗时不同抗凝方法的抗凝效果，并对影响患者预后的因素进行分析。

The major results obtained are: PCR-RFLP method is suitable for molecular identification of Shihu; 205 compounds were isolated from 10 species of Dendrobium, including 21 new compounds, and 28 compounds isolated from genus Dendrobium for the first time. Each of the extracts and compounds were screened for anticoagulant and antitumour activities separately. The results indicated that the ethyl acetate extract from Dendrobium chrysanthun has significant anticoagulant function; the antitumour function of the 4 bibenzyl components from Dendrobium chrysotoxum is stronger than that of phenanthrene, of which the erianin has significant anti-angiogenic effect both in vivo and in vitro; components with moderate or stronger antitumour activities were found in the extracts of D. thyrsiflorum, D. chrysanthun and D. trigonopus; quality standard for 5 species of Dendrobium was drawn up use active or indicative components as control.

重要研究结果有：经方法学研究，认为PCR-RFLP法适于作为石斛属药材分子标记鉴定方法；对10种石斛进行化学成分分离鉴定，共分得205个化合物，其中新化合物21个，首次从石斛属分得的28个；对提取物和各单体化合物分别作抗凝血、抗肿瘤等活性筛选，结果说明束花石斛乙酸乙酯部位有显著的抗凝血作用，鼓槌石斛的4个联苄类成分抗肿瘤作用强于菲类，联苄类毛兰素在体内外有显著抗血管生成活性，球花石斛、束花石斛及翅梗石斛均筛到中等或较强抗癌活性的成分；选择有活性或指标性成分作对照品，对5种石斛草拟了质量标准。

Celite activation markedly attenuated TFPI-mediated effects on coagulation kinetics, whereas TF activation accentuated TFPI-mediated prolongation of clot initiation and diminution of propagation.

硅藻土激活显著的弱 TFPI-介导的对凝血影响，然而 TF 激活强 TFPI-介导的延长凝血启和 TFPI-介导的血块增殖减少。

After the traumatic Femur fracture patients before,during and after the coagulation of blood compared with normal adults in a hypercoagulable state and in operation,after more than pre-operative hypercoagulability.

创伤股骨骨折后术前、术中、术后的凝血功能与正常成年人比较血液处于高凝状态且术中、术后比术前更为高凝。

Patients with SAP were in stable thrombotic state, patients with ACS were in unstable thrombotic state, the occurrence of ACS was closely related to hypercoagulable state.

稳定型心绞痛患者的凝血系统处于稳定状态，而急性冠状动脉综合征患者处于高凝状态，合并2型糖尿病或原发性高血压的急性冠状动脉综合征患者高凝状态更显著，提示高凝状态与急性冠状动脉综合征的发病密切相关。

Patients were randomly assigned to two groups, The one is chronic tonsillitis, the other was obstructive sleep apnea syndrome, Exclusion criteria of chronic tonsillitis included peritonsillar abscess history, bleeding disorders, and any other procedure together with tonsillectomy., Indications of chronic tonsillitis included intraoperative bleeding, operative time, postoperative pain, and return to normal diet were evaluated. Indications of obstructive sleep apnea syndrome included Intraoperative bleeding, operative time, Using spss11.0 software analyzed all the data.

实验设计和观察指标：选择慢性扁桃体炎患者30和鼾症患者30人，慢性扁桃体炎患者不包括伴随扁桃体周围脓肿患者，不包括有血液系统疾病和凝血障碍的患者，同时不包括扁桃体切除手术和其它手术同时进行的患者，鼾症患者不包括有血液系统疾病和凝血障碍患者，慢性扁桃体炎患者观察记录的指标包括手术时间﹑手术中出血量﹑术后疼痛时间和程度和正常饮食恢复时间，鼾症患者记录手术时间和手术中出血量，使用spss11.0软件对所有的数据进行描述性统计分析

The perioperative counts of Hemoglobin, haematocrit and platelet, and also the amount of blood savage blood or the allogenic blood transfusion of the 2 groups were recorded and compared.

进行比较，分别于两组患者术前、术后第1、3、5、14d各取病人静脉血，记录两组患者围手术期血红蛋白、红细胞比容、血小板计数、凝血时间、出血时间检测结果，分别记录术中回输的血量和输入异体血液量。

The change of agglutinating activity in different temperature and pH indicated that PML had no hemagglutinating activity at 80℃. The effect of chemical modification of amino acid residues upon hemagglutination was investigated. There was a definite decrease of fluorescence intensity which corresponds to the oxidation of tryptophan.

研究了不同温度、pH和变性剂对PML凝血活性的影响和荧光光谱的变化，当温度达80℃时，活性完全丧失；pH为4—9对活性影响不大，pH低于2和pH高于12时，大黑花芸豆凝集素的凝血活性大部分丧失；高温和强碱对荧光光谱有较大影响，表明PML对高温，强碱的耐受性不强。

The split between the two groups can hardly be papered over.

这两个团体间的分歧难以掩饰。

This approach not only encourages a greater number of responses, but minimizes the likelihood of stale groupthink.

这种做法不仅鼓励了更多的反应，而且减少跟风的可能性。