减轻体重法

General symptoms such as purpure in mucous membrance and skin, bleeding of internal organs, decreasing of weight and bad mental state caused by modeling were well improved in four control groups (Chinese traditional medicine group, western medicine group, PG original formula group and PG major formula group), the peripheral PLT was increased, spleen weight and its action of phagocytosis and damage to PLT were both decreased, morrow megakaryocytes differentiation and maturation were improved and hyperplasia descended, which showed significant differences compared with the model group. Differences among the four control groups were not significant. The optimal dose ratio of PG major formula was finded out with homogeneous design software UST3.0 and multiple regression: Astragalus root 48g, Rhubarb 15g, peach kernel 1Og, Agrimony 24g.

结果：模型建立成功；中、西药对照组、紫癜颗粒核心方组与原方组小鼠对于免疫法造模所引起的皮肤粘膜紫癜、内脏出血、体重减轻、精神状态差等一般症状均有较好的改善；小鼠的外周血小板计数得到提高；脾脏均重及对血小板的吞噬破坏降低；骨髓巨核细胞分化成熟程度增高，增生活跃度降低，与模型组相比较，均有显著性差异，四个对照组之间无显著性差异，利用均匀设计UST3.0统计软件分析，进行多元逐步回归处理，筛选出紫癜颗粒核心方的最佳剂量配比为黄芪48g，大黄15g，桃仁10g，仙鹤草24g。

The results showed that LRK could significantly inhibit the mammary hyperplasia caused by estrin, reduce the content of serum 〓, raise P level, promote the production of DA in hypothalamus and mammary tissue, decrease the release of 5-HT, inhibit the secretion of serum PRL, reduce the sensitivity of mammary tissue to estrin and progestogen, prevent the expression of mammary tissue on PCNA, the effect was equal to triphenylamine oxide, obviously superior to the control group of Ru Zeng Ning.

通过实验研究，建立了具有肾虚肝郁证侯群的乳腺增生病理模型，利用免疫组化技术、图像分析系统、荧光分光光度法、放射免疫法等现代医学研究方法，从病理形态学、医用体视学、神经内分泌学、阴道细胞学等方面，观察了利乳康口服液对模型动物整体状态、乳腺组织病理形态、血清激素、神经递质以及卵巢功能的影响，结果表明利乳康口服液能明显抑制雌激素引起的乳腺组织增生，降低血清E〓含量，升高P水平，促进下丘脑及乳腺组织中DA的产生，减少5-HT释放，抑制血清PRL分泌，降低乳腺组织对雌、孕激素的敏感性，阻止乳腺组织PCNA的表达，其效应与三苯氧胺相当，明显优于乳增宁对照组；另外，利乳康口服液还能缓解模型动物肾虚肝郁证侯群，增加其体重，调节其整体状况，改善模型动物不规则动情周期，减轻其子宫及卵巢的病变，抑制子宫内膜的过度增长，调节卵巢功能，揭示了中药利乳康口服液对神经内分泌和卵巢功能的整体调控作用，以及对本病发生、发展的预防作用

There is no significouldt variation between the function of Method 1 and 3 in the indexes of digestive and absorptive function,except the effect on body weight and food intake;as well,model 2 shows no significouldt influence on the indexes besides body weight lose.1.4 ConclusionsContrast the three modeling methods,model 3 is the most obvious and steady method for the establishment of deficiency of spleen YANG.2 comparison on the efficacy of Lizhong Pills influenced by dried ginger and its different components on digestive and absorptive functions and energy metabolism2.1 ObjectivesThis research was designed to observed the different influences of Lizhong Pills formula on the models,which contains dried ginger or its main group of components(volatile oil and water solubles).It would be explored from two levels of material base,single herb dried ginger or its different components,to confirm that the whole effects of Lizhong Pills do mainly depend on its main herb dried ginger in the formula just as the traditional acknowledgement in TCM.Further more,the connotative meaning of dried ginger used as the main herb in Lizhong Pills egthe aspect of pharmacology and chemistry would be preliminary revealed.2.2 MethodsEach group of model rats of deficiency of spleen-YANG were to be duplicated by method 3 for 14 days,and be treated by corresponding drug samples for 8 days.

造模方法1对消化吸收相关药理指标的改变与造模方法3的影响相似，但对模型动物的体重和食量的影响不明显；造模方法2除能使模型动物的体重减轻外，对其他各指标均无显著影响。1.4结论对比实验采用的三种石膏-知母的给药方法，方法3的造模效果最为显著和稳定，即以每日灌胃给药，连续12天，恢复9天，是本实验证实的最有效的脾阳虚证候模型制备方法。2干姜及其不同有效部位对理中丸消化吸收功能及代谢的影响2.1目的通过对理中丸中君药干姜，以及干姜中挥发性成分和水溶性成分对理中丸主要功效影响的研究，从药味和化学成分群两个层次，证实君药干姜及干姜中的主要活性成分群对理中丸整体功效的决定性影响，以初步揭示理中丸中君药核心地位的药理学和化学内涵。2.2方法采用石膏-知母复合造模法制备大鼠脾阳虚证候模型，造模期为14天1；治疗期间各给药组分别给予治疗药物，连续给药8天。

The results indicated that the mutant protein promoted the survival of dorsal root ganglion、induced TF-1 prolification and made the normal mice lose weight,decrease appetite and reduce fat index.The weight loss effect was dependant with its administration dosage,ED50 was 150.986?

结果是突变体蛋白能促进鸡胚背根神经节的生长；促进TF-1细胞增殖，MTT测定法表明突变体蛋白与国际参考品相比，比活不低于2.0×106U/mg；使正常小鼠的体重减轻，摄食量减少，脂肪指数下降，并且体重的减轻与突变体蛋白的给药剂量呈现良好的剂量依赖关系，其ED50为：150.986？

Singer Leona Lewis and former Led Zeppelin guitarist Jimmy Page emerged as the bus transformed into a grass-covered carnival float, and the pair combined for a rendition of "Whole Lotta Love".

歌手leona刘易斯和前率领的飞艇的吉他手吉米页出现巴士转化为基层所涵盖的嘉年华花车，和一双合并为一移交&整个lotta爱&。

This is Kate, and that's Erin.

这是凯特，那个是爱朗。