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Results①Make clear of the general principal during the morphologicaldevelopment of the C57BL/6 mouse inner ear and reconstructed the 3D modelof E13 inner ear;②The mature time of many histological structuresassociated closely with the hearing setout of C57BL/6 mouse were madeclear as basilar membrane in D10, scala vestibular and tympanicD4, Cortis tunnel D12, inner sulcus D10, tectorial membrane D10, haircells D12, spiral ganglion neurons D12 and neurofilament in cochlear axisD12-D14.③Outlined the time table and the patterns of the expressionsof those proteins associated with the inner ear development which includedproneural committed proteins, neuronal differential proteins,neurotrophic factors and neuron special proteins.

结果①HE常规染色大体观上了解了C57BL/6小鼠内耳形态发育E8-Da期间的一般规律并且获得了E13的三维立体图像;②获得了各种听功能密切相关的结构的成熟时间点,基底膜(D10)、鼓阶前庭阶(D4)、螺旋器隧道(D12)、内螺旋沟(D10)、盖膜(D10)、毛细胞(D12)、螺旋神经元(D12)和蜗轴纤维(D12-D14);③完成了前神经决定蛋白、神经分化蛋白、神经营养因子和神经元特异性蛋白等内耳发育相关的蛋白的表达时限表并详细观察了其在内耳各个部位表达随发育变化的特点:④Calbindin在E16以后的螺旋神经元没有表达,但是在scarpa神经元持续表达。

Results①Make clear of the general principal during the morphologicaldevelopment of the C57BL/6 mouse inner ear and reconstructed the 3D modelof E13 inner ear;②The mature time of many histological structuresassociated closely with the hearing setout of C57BL/6 mouse were madeclear as basilar membrane in D10, scala vestibular and tympanicD4, Corti\'s tunnel D12, inner sulcus D10, tectorial membrane D10, haircells D12, spiral ganglion neurons D12 and neurofilament in cochlear axisD12-D14.③Outlined the time table and the patterns of the expressionsof those proteins associated with the inner ear development which includedproneural committed proteins, neuronal differential proteins,neurotrophic factors and neuron special proteins.

结果①HE常规染色大体观上了解了C57BL/6小鼠内耳形态发育E8-Da期间的一般规律并且获得了E13的三维立体图像;②获得了各种听功能密切相关的结构的成熟时间点,基底膜(D10)、鼓阶前庭阶(D4)、螺旋器隧道(D12)、内螺旋沟(D10)、盖膜(D10)、毛细胞(D12)、螺旋神经元(D12)和蜗轴纤维(D12-D14);③完成了前神经决定蛋白、神经分化蛋白、神经营养因子和神经元特异性蛋白等内耳发育相关的蛋白的表达时限表并详细观察了其在内耳各个部位表达随发育变化的特点:④Calbindin在E16以后的螺旋神经元没有表达,但是在scarpa神经元持续表达。

Chapter Ⅱ Xenopus Tbx6 Mediates Presomatic Mesoderm Cell Adhesion during Somitogenesis As a member of T-box gene family, Tbx6 is involved in somite cell fate decision and endows adhesion properties to mesoderm cells.

第二章 xTbx6在体节发生过程中介导了预定体节中胚层的粘连 xTbx6是T-box转录调控因子家族的成员,xTbx6参与体节细胞命运决定和赋予旁侧中胚层细胞特定的粘连特性。

In this study,we focused on the functional analysis of HOXD 13 p.Q317R mutant and polyalanine expansion mutant.PartⅠ:Functional Analysis of the HOXD13 p.Q317R Mutant Associated with Syndactyly TypeⅤHox gene encodes a family of transcription factors of fundamental importance for body patterning during embryonic development.

第一部分HOXD13同源盒p.Q317R点突变的功能分析同源盒基因(homeobox genes,Hox genes)编码一个高度保守的转录因子家族,在决定胚胎期细胞的定向分化与增殖以及调控机体组织器官的发育过程中起关键性作用。

CAI courseware can lead to the testee's diversified situational interest. Courseware with novelty and moderate challenge will increase the testee's situational interest. Pleasure factor in courseware I can explain the 47% of the whole variables, while Pleasure factor in courseware II can explain the 56% of the whole variables.

课件制作的新颖性和适度的挑战性有利于个体情境兴趣的提高,而个体学习过程中的即时愉悦感和探索倾向在很大程度上决定其情境兴趣体验水平,在课件Ⅰ中,愉悦感因子可以解释总体变量47%的(R~2=0.47),在课件Ⅱ中可以解释总体56%的变异性(R~2=0.56)。

It is very important for yong mammalian. This article reviewed the thermogenesis mechanism and differentiation of brown adipose tissue.

文中阐述了棕色脂肪组织的产热机制,介绍了影响棕色脂肪细胞的分化、决定棕色脂肪组织生理功能的关键因素解偶联蛋白和PPARγ的辅助激活因子PGC-1α,讨论了影响棕色脂肪组织功能的因素。

Tolerance relations played a key role in resolving setup sequences, and tolerance factor introduced to normalize the geometric tolerance and dimensional tolerance.

其中公差关系为混合图中决定定位顺序的重要关键,本文以综合公差因子对几何公差与尺寸公差进行一致性的比较。

After that, using Taguchi Method to find the main influence factor of warpage and determine the best shaping condition.

其次,以田口方法探讨影响翘曲的主要因子,并决定出最佳制程条件。

The ubiquitin proteolytic system is an important selective proteolytic system of the celler proteolytic systems, a number of them were identified as a ubiquitin chain assembly factor-E4. The U-box protein is a new family ubiquitin-protein ligase(E3), which determine the substrate specificity of ubiquitination. The U-box is a domain of 70 amino acids that is highly conserved among yeast, plant and animals, but more U-box proteins were found in plants than in animals.

泛素系统是选择性降解细胞内蛋白质的重要系统之一,U-box蛋白质是此系统中决定底物特异性识别的一种新型E3蛋白质,部分U-box蛋白质属于泛素链聚集因子-E4.U-box结构域大约由70个氨基酸残基构成,在酵母、植物和动物等真核生物中保守存在,但植物中的数目远多于动物中。

The soil had the alkalize characteristic, and the decisive factors were terrain, texture and precipitation, so before the haloxylon ammodendron settled down, the soil had the alkalize characteristic, and the haloxylon ammodendron was alkali-resistant plant, but if the total alkalinity excessively high, the haloxylon ammodendron also grew difficulty.

土壤具有碱化特征,主要是由地形、质地、降水等结构性因素决定的,由此得出荒漠植被梭梭定居之前土壤就具有了碱化特征,梭梭是耐碱性荒漠植被,但总碱度过高的区域梭梭也难以生长,因此土壤酸碱度仍然是该区域影响梭梭生长和分布的重要因子。

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By the time of its fall, most of the prisoners were writers who had written against the corruptions of the government.

到它被攻陷的时候,里面多数的犯人是写了反对政府贪污文章的作家。

The most obvious variation to ovum morphological character was that the color was changed from light green to sepiaceous in embryonic development, and all the ovums were almost hatched after 96h.

在胚胎发育过程中卵的形态特征最明显的变化是颜色从淡绿到深褐色,卵在发育96h后卵基本全部孵化。

There was a conflict between plebs and patricians in ancient Rome in 494BC.

在公元前494年,罗马发生了一次平民反对贵族的斗争。