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The major biological function of triglyceride was energy storage and supplement especially in the condition of cell suffered from energy. In the meanwhile, the triglyceride also decomposed and releases H2O that stimulate metabolic function and biochemistry reaction of the cell. Above all the mention, cholesterol and triglyceride were indispensable in the normal physiological function in the human body. In the recent years, the hypertension, diabetes mellitus, stroke and coronary artery diseases were very popular and suffered from many people that lack of exercise, changes life style and diets habits leading to increase crapulence, tension, obesity and aging. Above all the diseases were very concerned with the hyperlipidaemias.

三酸甘油酯最主要的功用是作为能量贮存的场所,并且在人体需要的时候,适时提供能量的补给,同时提供水份,以维持细胞以及组织新陈代谢的进行,所以,胆固醇和三酸甘油酯都是维持正常生理活动所不可或缺,但是近年来由於国人的生活方式及饮食习惯的改变,工作紧张忙碌,应酬多而且暴饮暴食,缺少运动,肥胖人口增加,以及人口结构日趋老化,使得高血压、糖尿病、脑中风及冠状动脉心臓病逐渐成为国人最常见的疾病,而上述这些疾病和高血脂症有极其密切的关系。

Objective To study the effects of statins on CRP and IL-6,and to evaluate the influence of statins on nflammation of vessel.Methods Observing CRP and IL-6concentration varieties on patients with coroˉnary artery disease before and after giving statins,evaluating the varieties of CRP and IL-6on the patients with high lipemia and normal lipemia,and assessing the effects of statins.

目的 研究他汀类药物对IL-6和CRP两炎症因子的作用,从而了解它对血管炎症的影响方法评估冠状动脉疾病的患者用他汀类药物后CRP和IL-6的变化,并分别评估高血脂和血脂正常患者IL-6和CRP的变化,以及他汀类药物对两组患者的作用。

However, at least 1 outside observer urged caution in interpreting these findings."The reliability and validity of high-resolution computerized tomography in kidney failure has been questioned," Ell Friedman, MD, nephrologist and Distinguished Teaching Professor of Medicine at the State University of New York Downstate Medical Center in Brooklyn, told Medscape Nephrology . He cited a recent study by Barraclough et al ( Nephrol Dial Transplant . Published online before print May 1, 2008) showing significant imprecision in HRCT-derived validation of coronary calcification in kidney failure patients, depending on who reads the results.

然而,至少一位以上的外部观察者表示在阐释这些研究发现时必须特别小心,布鲁克林纽约州立大学Downstate医学中心的肾脏学家与卓越教学医学教授Ell Friedman医师向Medscape肾脏学表示,高解析度电脑断层扫描应用於肾脏衰竭上的信度与效度已经受到质疑;他引用最近一项由Barraclough等人(发表於Nephrol Dial Transplant,於2008年5月1日线上发表)的研究结果,显示HRCT延伸的肾脏衰竭病患冠状动脉钙化检验有相当程度的误差,取决於谁判读检验结果。

The statistical difference of proinsulin rather than HOMA index was found among the patients of various Gensini's score group (Gensini's score was examined as a categorical variable classified by tertile values) and significantly stenosed vessels group by means of the results of analysis of covariate variance after adjusting for age, sex and body mass index (p<0.05), and the partial correlation coefficient between proinsulin level and Gensini's score, the number of significantly stenosed vessels after adjusting for age, sex and body mass index was 0.3156 (P<0.01) and 0.2752 (P<0.05) respectively. Multivariate linear regression analysis indicated that the level of proinsulin was positively correlated with the Gensini's score (P<0.01). The results of multivariate stepwise Logistic indicated that the proinsulin was the independent risk factor for the coronary heart disease, and the odds ratio (95% confidence interval) was 2.268 (1.253~4.105)(P=0.007), however, the HOMA was refused by the final model.

年龄、性别与体重指数为控制变量的协方差分析结果显示,胰岛素原的水平在不同的Gensini评分组、冠状动脉病变血管数分组中分布有统计学差异(P<0.05),偏相关分析示胰岛素原的含量与Gensini评分与病变血管数显著正相关,其偏相关系数分别为0.3156(P<0.01)与0.2752(P<0.05),而HOMA指数与两种评分的相关未有统计学意义;多因素线性逐步回归分析结果示胰岛素原水平与Gensini评分独立正相关(P<0.01);多因素Logistic回归分析显示,胰岛素原的水平为冠心病的独立的危险因素,其OR值及其95%可信区间为2.268(1.253~4.105)(P<0.01),HOMA指数未进入模型。

Role of endothelial function and inflammation in patients with cardiovascular risk factors, with and without a history of myocardial infarction;Comparison of gated blood pool SPECT and multidetector row computed tomography for measurements of left ventricular volumes and ejection fraction in patients with atypical chest pain: Validation with radionuclide ventriculography;Plasma adiponectin, T94G gene polymorphism and PAI-1 in patients with and without hypertension;Prognostic value of myocardial perfusion imaging in symptomatic and asymptomatic patients after percutaneous coronary intervention;Impact of early initiation of intravenous therapy for acute decompeusated heart failure on outcomes in ADHERE……

文章摘要:内皮功能和炎症在有或无心肌梗死病史的具有心血管危险因素患者中的作用;门控血池SPECT和多层螺旋CT对于测量不典型胸痛患者左室容积和射血分数的比较:以放射性核素心室造影检查进行验证;有或无高血压的患者的血浆脂联素、T94G基因多态性和PAI-1;心肌灌注成像对经皮冠状动脉介入后有症状和无症状患者的预后评估价值;ADHERE中早期开始静脉用药治疗急性失代偿性心力衰竭对预后的影响

Transcendental meditation (20 minutes twice daily of silently chanting a mantra with eyes closed) was found in a small controlled trial to reduce angina-like chest pain and to normalize electrocardiograms in patients with cardiac syndrome X, a form of angina in people with otherwise normal coronary arteries. 40 While these patients did not have angina in the classic sense, their chest pain was thought to result from anxiety, which may reduce blood flow to the heart, and their ECGs resembled those of classic angina patients.

超越冥想(每日两次,每次20分钟的默念咒语眼睛关闭了一个小对照试验发现,以减少心绞痛样胸痛,并正常化心脏X综合征的心绞痛在人们的患者心电图)而与其他正常的冠状动脉。40虽然这些病人并没有在传统意义上的心绞痛,胸部疼痛被认为是导致焦虑,这可能减少血液流向心脏,其心电图的形状类似心绞痛患者的典型。

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