再折叠

Although human leptin has been shown to dimerize during refolding procedure, the exact dimerization mechanism still remains unillustrated.

在前期研究中，已发现人瘦素在体外再折叠过程中会形成稳定的二聚体，但其二聚化机制尚不清楚。

Do not refold your napkin, but don't wad it up, either.

你不要再折叠餐巾，但也不要随意的卷起来

Do not refold your napkin or wad it up on the table either.

你也不要再折叠餐巾或把它随意的卷起来放在桌子上。

The three-dimensional fold of the Gamma crystallin has been solved and the protein can be refolded in vitro .

晶状蛋白可在试管内再折叠且其三维立体结构已经被解出。

The purified TGF β1 monomer protein can form into active dimeric TGF β after refolding in vitro.

纯化的TGFβ1单体蛋白通过体外再折叠可以形成具有生物活性的TGFβ1双体分子。

A potential approach to this problem is to make use of a natural defense mechanism called " the stress response," which is characterized by a transient down - regulated synthesis of nonvital cellular proteins and increased production of endogenous protective factors known as heat shock proteins that act to allow proper refolding of proteins denatured by the incipient injury.

应激反应的特征是一过性下调细胞非必需蛋白的合成及增加被称为热休克蛋白的内源性保护因子的合成。热休克蛋白作用是促使损伤导致变性的蛋白适当地再折叠。HSP家族中HSP70被认为在细胞保护中发挥重要作用。

In accordance with the invention, the hG-CSF protein can be prepared with high purity through rather simple process facilitating secretion of large amount of hG-CSF fusion protein into the periplasm, which does not require complicated processes such as solubilization and subsequent refolding required for isolation of the hG-CSF protein produced in cytoplasm as insoluble inclusion bodies by conventional techniques, thus, the hG-CSF protein can be widely used as an active ingredient in the development of supplementary agents for anticancer therapy.

根据本发明，通过促进大量hG－CSF融合蛋白分泌到周质中的相当简单的方法可以高纯度制备hG－CSF蛋白，所述方法不需要复杂的加工过程例如对于通过常规技术分离胞质中产生的作为不溶性包函体的hG－CSF所需的溶解和随后再折叠，因此，在开发用于抗癌治疗的补充药物的过程中可用hG－CSF蛋白广泛地作为活性成分。

2 Is a good model for studying dissociation and reassociation during unfolding and refolding.

肌酸激酶是研究蛋白质去折叠和再折叠过程中解聚和再聚合的模型蛋白之一。

The results showed that rate limiting step during reassociation of creatine kinase subunits existed in the refolding pathway under the various conditions.

结果显示肌酸激酶再折叠过程中，亚基的再聚合是限速步骤。

In contrast, deletion of the propeptide yields mature but inactive NK, the inclusion bodies of NK or denatured rNK couldn't be renatured in any condition, but with the aid of exogenously purified propeptide or Ser221Ala proNK, the inactive mature protein could be renatured by an intermolecular pathway in vitro.

此外，我们利用融合基因表达系统在大肠杆菌中高效表达了谷胱甘肽S-转移酶／NK和硫氧还蛋白／NK两种融合蛋白，经体外复性、纯化，均获得活性蛋白。以上结果显示，pro肽在体内体外，通过分子内或分子间的方式均能帮助NK分子的折叠与再折叠，作为一种分子内的分子伴侣，pro肽为NK分子正确折叠所必需。

The basic concept of FOP can be summarized as to further optimize effective prescription according to the standard of curative effects and with the aid of modern science and technology and theories of traditional Chinese medicine.

其基本内涵可概括为：以确有疗效的中药复方为研究对象，以现代科学技术和传统中医药理论为技术支持，以该复方所治病证的药效响应为评价标准，以优化重组疗效更优的新复方为研究目的。

Ever since our world has been a world, native forests have been indiscriminately exploited by man.

自从我们的世界一直是世界原生森林被任意剥削人。