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Experimental solubilities of terephthalic acid dissolved in N,N-dimethyl propionamide, N,N-diethyl propionamide and N,N-diethyl acetamide were determined in the temperature range of

测定了303.2~363.2K温度范围内,对苯二甲酸在N,N-二甲基丙酰胺、N,N-二乙基丙酰胺和N,N-二乙基乙酰胺中的溶解度。

High expression of cellular asparagine synthetase is a causative factor for the resistance of leukemic cell to Lasparaginase therapy.

细胞内门冬酰胺合成酶(asparagines synthetase, AS)的表达水平与白血病细胞对左旋门冬酰胺酶耐药有关。

OBJECTIVE: To study the cellular activity of asparagine synthetase in different types of childhood acute lymphoblastic leukemia.

目的:不同类型急性淋巴细胞性白血病对左旋门冬酰胺酶敏感度不完全相同,由于LAsp活性水平与细胞内门冬酰胺合成酶活性负相关,因此研究不同类型ALL患儿白血病细胞内门冬酰胺合成酶活性水平分布情况,有助于临床治疗中合理使用LAsp。

The absorption of root system was the main sources of nitrogen in the plant.The effects of matrix ventilation on the abaorption,transportion and metabolism of nitrogen in the root system of cucmber were discussed deeply.The results showed that contents of ammonium,nitrate,free amino acids and soluble protein in cucumber roots were higher in G1 treatment.Contents of ammonium,nitrate and free amino acids in cucumber roots were the trend of the dropping after the first rising in F1 treatment,but contents of soluble protein was lower11.03%than that of the control.

根系吸收是植物体内氮素的主要来源,本研究深入探讨了基质通气状况对黄瓜根系氮素吸收、运输和氮代谢的影响,结果表明G1通气处理根系的铵盐、硝酸盐、游离氨基酸和可溶性蛋白含量均较高;非通气处理(F1处理)根系内铵盐、硝酸盐和游离氨基酸含量呈先升高后降低的趋势,而可溶性蛋白含量始终较低,比对照降低11.03%。G1处理根系硝酸还原酶、亚硝酸还原酶、谷草转氨酶、谷丙转氨酶、谷氨酰胺合成酶活性均较高;而F1处理的酶活性在处理末期显著降低,其中谷氨酰胺合成酶活性比对照降低33.33%。

They had suppressed the cathodic process of carbon steel electrode. Their inhibition performance was also related with their molecule stereo conformation and electron configuration. Four of bis-(1, 1'-benzotriazoly)-α,β-diamide compounds linked via-CO 〓CO-chain were synthesized and certified by IR and 〓H-NMR. The minimum energy conformations of these compounds were obtained by MM2 forcefield program. The two benzotriazole moiety in BBT1 was more planar than in other compounds. This was beneficial in increasing the inhibition effects of BBT1. In 0.5M H〓SO〓 solution, BBT1 suppressed anodic corrosion reaction. In 3%NaCl solution, BBT1 suppressed both cathodic and anodic corrosion reactions. 1- [ (1'-imidazolly)-methyl] benzotriazole was synthesized by Mannich reaction.

合成了四个通过-CO〓CO-连接的双(1,1'-苯并三唑)-α,ω-二酰胺化合物,采用MM2分子力学程序优化了它们的分子结构,双(1,1'-苯并三唑)-α,ω-二酰胺化合物的缓蚀作用与其分子内两个苯并三唑单元的空间取向有关系,良好的平面性有利于苯并三唑二聚体的吸附和缓蚀作用,苯并三唑二聚体BBT1分子内两个苯并三唑单元近似平行,所以显示出较好的缓蚀效果。0.5M硫酸中BBT1主要抑制铜的阳极溶解的电化学反应;3%NaCl溶液中,BBT1对铜的阳极溶解和氧的阴极还原过程均有抑制作用,相比较而言对阴极过程的抑制作用更大一些。

The cis novel bisoxazoline ligands L1-L4 have been synthesized through the treatment of new cis dihydroxy diamide with p-toluenesulfonyl chloride in the presence of catalytic quantity of 4--pyridine, and the cis dihydroxy diamide could be achieved from the condensation of the amino alcohols and cis cyclopropane dicarbonyl chloride prepared via oxidation and halogenation from cis-2,2-dimethyl-3-formylcyclopropanecarboxylate with DCC.

我们以蒈醛酸内酯为起始原料,经过氧化反应、酰氯化反应得到顺式环丙烷二酰氯,然后在二环己基碳二亚胺的催化下与相应的氨基醇反应合成了顺式二羟基酰胺,再用对甲苯磺酰氯将羟基活化,最后在二甲氨基吡啶的催化下关环合成顺式双噁唑啉配体L1~L4。

In order to know more about the microcosmic structure of the important biochemical model molecule formamide in aqueous solution, the Optimized Potentials for Liquid Simulations-All Atom model were used in the molecular dynamics simulation for the aqueous solution of FM in the whole concentration range. The radial distribution functions of the solutions were obtained. The interaction between water molecule and FM molecule was analyzed and calculated.

为了解重要的生化模型甲酰胺在水溶液中的微观结构,采用全原子力场在全浓度范围内对甲酰胺溶液进行了分子动力学模拟,得到了溶液的径向分布函数,分析计算了溶质和溶剂分子间的相互作用,对甲酰胺和水分子的氢键缔合情况进行了分析。

Computationalresults indicate that the no-planar trans-benzanilide is the most stable structure. The spectra indicate that the Franck Condon region photodissociation dynamics have multidimensional character withnine activemodes. The intensity of υ24 mode in methanol is much stronger than that in acetonitrile. Compared with fatty amides and benzamide, phenyl substitution for H atom on-NH2 group makes C=O solvent effects disappear.

结果表明,苯甲酰苯胺的非平面反式结构为最稳定结构;在Frank-Condon区域内,苯甲酰苯胺主要由9个活性振动模组成;其中ν24(苯环上C=C不对称伸缩振动和CCH的面内弯曲振动,NH面内弯曲振动)振动模在甲醇溶剂中的强度远远大于其在乙腈的强度;与脂肪酰胺类化合物和苯甲酰胺的研究结果比较发现,苯基取代-NH2上的H原子使得C=O不再具有明显的溶剂效应。

objective to study the effects of berbamine and batiolun on ldh metabolizability in the process of increasing leukocyte.methods enzyme biochemical techniques is used to study the effect of berbamine and batiolˉun in the process of inceasing leukocyte and also to study the effect of ldh metabolizability.results when leukocyte is inhibited by the immune inhibitor cycolophosphamcide,berbamine and batiolun are compared of the effect of ldh activity.conclusionthe study draws the conclusion that both berbamine and batiolun can increase thegranule cell,and they also have some effect of the ldh metabolizability.

目的 研究小檗胺和鲨肝醇升高白细胞作用及对细胞内ldh的代谢的影响。方法采用酶细胞化学方法,对两种药物在治疗由免疫抑制剂环磷酰胺所致的白细胞减少症时,对乳酸脱氢酶活性的影响进行了比较观察。结果小檗胺和鲨肝醇均可升高粒细胞,同时对细胞内ldh的代谢有一定的影响。结论小檗胺和鲨肝醇能使外周血粒细胞增加,可用于治疗多种因素引起的白细胞减少症。

There is a close relationship between monoamines and learning and memory. NE and dopamine are believed to have a role in facilitation of memory. For this, an observation of clausenamide on monoamines and their metabolites as well as monoamine oxidase B activity was carried out.

目前认为脑内单胺类递质的变化与学习记忆密切相关,其中DA,NE的增加有助于学习记忆的形成,为了探讨黄皮酰胺的促智作用机制,我们首先研究了黄皮酰胺对小鼠脑内单胺类递质及其代谢产物和单胺氧化酶的影响。

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