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A series of five-membered lactams containing 1, 3-diene moity were prepared by RCEM reaction, the scope of this reacrion was expanded.

在上述研究的基础上,我们利用烯炔关环复分解反应合成了一系列含 1, 3-二烯结构单元的五元内酰胺化合物,从而进一步拓展了关环复分解反应的应用范围。

Coil and B. subtilis using the β-lactamase distribution assay. The results showed that the β-lactamase activities of E.coli are mainly in periplasm while the enzyme produced by B.

内酰胺酶活力测定表明,大肠杆菌产生的酶主要积累在周质空间,而枯草芽孢杆菌产生的酶主要分泌在胞外。

This could be a fascinating method for the practical syntheses of chiral synthons as valuable building blocks and important medicinal intermediates.3.Series of novel optical pureγ-aryl-1H-1,2,4-triazole derivatives were designed and synthesized by using the chiral auxiliary(Oppolzer\'s sultam),and all these target compounds were structurally characterized by ~1H NMR,~(13)C NMR,MS and elemental analysis,at the same time,some representative compounds have been elucidated by X-ray diffraction analysis.

应用手性辅剂樟脑磺内酰胺的手性诱导作用,设计合成了一系列光学纯的γ-芳基-1H-1,2,4-三唑类衍生物,所有目标化合物都采用了~1H NMR、~(13)C NMR、MS和元素分析进行了结构表征,同时也获得了部分代表性化合物的晶体结构,进一步确证了化合物的结构。

Whereafter,we achieved a highly enantioselective approach towards the synthesis ofβ-substituted chiral ketones utilizing Oppolzer\'s sultam as chiral auxiliary.The-and-enantiomer of target chiral ketones were obtained with up to 99%ee.

应用手性辅剂樟脑磺内酰胺的手性诱导作用,高对映选择性地合成了一系列β-芳基取代手性酮,其ee值高达99%,可用于药物及其它精细化工中间体的不对称合成。3。

Objective To modify the synthesis of Benzhydryl 2α- methyl - 2β- [ ( 1,2,3 -triazol - 1 - yl)- methyl ] penicillanate - 1,1 - dioxide, the key intermediate of β- lactamase in-hibitor tazobactam.

目的 改进β-内酰胺酶抑制剂泰唑巴坦关键中间体2α-甲基-2β[(1,2,3-三唑-1-基)-甲基]青霉烷酸砜二苯甲酯的合成。

Objective To screening sensitive test to detesting on ESBLs of Klebsiella pneumonia(KL.pneumonia )and E scherichia,study relation between ESBLs and resistance to antibiotics of KL.pneumonia and E.coli,provide suggestions empirical treatment against the bacteria.

摘 要]目的:筛选检测肺炎克雷伯氏菌及大肠杆菌的超广谱的β内酰胺酶的敏感方法,并探讨肺炎克雷伯氏菌及大肠杆菌产ESBLs的情况与耐药的关系,为临床合理使用抗生素提供实验依据。

The main by-product s and their separation and recovery technologies were discussed for cyclohexanone gas-phase Beckmann rearrangement.

探讨环己酮肟气相Beckmann重排主要副产物及其分离回收方法,研究1-氮杂-2-乙氧基-1-环庚烯、1,3,4,5-四氧吖庚因-2-酮及其同分异十句体等副产物回收利用生成已内酰胺的方法。

It is widely used for textile industries like cotton and wool spinning, carpet industry, garment, lining cloth and automobile tires.

无锡市怡嘉国际贸易有限公司成立于2002年10月,公司主要经营化工原料几内酰胺,它广泛应用于棉纺、毛纺、造纸、毛毯、服装、衬布、汽车轮胎等行业。

AIM: To evaluate the efficacy and safety of the amoxicillin and potassium clavulanate chewable tablets.

由阿莫西林和β-内酰胺酶抑制剂克拉维酸钾组成的复方制剂在临床上的应用日趋普及。

Then we completed the first total synthesis of-Plakoridine A using Eschenmoser couping reaction as akey step. During the synthesis we found the choice of protecting groups and the configuration of the chiralcenter of the substrate play an important role to the key Eschenmoser reaction,so we think our successwould be of guide for synthesizing other polysubstituted pyrrolidines or piperidines.

在论文的第一章中,我们先以易得的对羟基苯乙酸乙酯为原料经多步反应制得了所需的β氨基酸酯,然后利用立体选择性的Aldol缩合反应和内酰胺化反应制得了Plakoridine Alactam,随后,以Eshenmoser缩合反应为关键步骤完成了生物碱-Plakoridine A的首次不对称全合成。

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This one mode pays close attention to network credence foundation of the businessman very much.

这一模式非常关注商人的网络信用基础。

Cell morphology of bacterial ghost of Pasteurella multocida was observed by scanning electron microscopy and inactivation ratio was estimated by CFU analysi.

扫描电镜观察多杀性巴氏杆菌细菌幽灵和菌落形成单位评价遗传灭活率。

There is no differences of cell proliferation vitality between labeled and unlabeled NSCs.

双标记神经干细胞的增殖、分化活力与未标记神经干细胞相比无改变。