内转

Smo protein is a transcriber in the Sonic hedgehog signaling pathway. Its anactivator that change extracellular Shh signal into intracellular Gli1 signal, thusinitiate the gene transcription in the cell nucleus.

Smo蛋白是Sonic hedgehog信号通路中的信息转换器，它能够把细胞外的Shh信号转换成细胞内的Gli1信号，从而启动细胞核内基因的转录，对Sonic hedgehog信号通路具有激活作用。

Following the booster dose, a robust anamnestic response was developed in all of 8 intramuscular revaccinees and 11 controls but 16 of 18 intradermal revaccinees, who lost anti-HBs of≥10 IU/L over time, and geometric mean titers of anti-HBs climbed to 208, 105, and 549 IU/L, respectively.

抗-HBs阴转者（肌肉、皮内复种和应答对照分别为8、18和11人）在加强1针后，除2名皮内复种者外，均产生了强劲的抗体回忆应答

According to analysis of flow field and velocity distribution in the mix tank,the results indicate that:using draft-tube in the mix tank,the axial flowing of liquid can be increased,the circumgyration around the impeller will be improved,and the strong mixed effect can be gained.

通过对有、无导流筒的搅拌槽内流场和速度的对比分析表明：导流筒强化了搅拌槽内上下液体的整体轴向流动，在近浆区域改善了液体的跟转，有强烈的混合效果，并且，在较为理想的流场分布下，有导流筒的搅拌槽功率消耗比无导流筒搅拌槽节省12%，其结果将为搅拌槽的整体结构优化提供有效途径。

The former stimulates the cells and transfer the signals into the cells through the ligation with receptors on the cell membrane. The latter, a derivative of nucleotide, causes a cytotoxic effect to suppress thymidylate synthetase activity, and, therefore, to damnify RNA and DNA synthesis.

前者通过与细胞表面的受体结合，把胞外刺激传递到胞内，诱导免疫受体介导的信号级联放大作用，引起一系列免疫效应；后者是是小分子的核苷酸衍生物，可直接进入细胞内，通过抑制胸苷酸合成酶及损伤RNA、DNA等对基因转录和核苷酸代谢产生影响，最后产生细胞毒效应。

Other methyl nucleophiles includingMeMgBr, MeCeCl2, MeTiCl3, Me3Al, Me3ZnMgCl, MeMnClwere tried, but in all these cases no detectable amount of exo-C8-methylated product was obtained. Although protecting C3-carbonyl as 1,3-dioxolanes could be achieved, the serious enolization of C8-carbonyl was still problematic. Converting C9-furan ring to α,β-butenolide did depress the enolization, but desired C8-methylation was completely replaced by migration of the double bond of the butenolide.

在本论文的早期阶段，主要着眼于解决二环[3.2.1]-C8-羰基加成甲基所遇到的C9-呋喃环差向异构化和C3与C8两个羰基之间化学选择性的问题：通过引入不同金属降低甲基试剂的碱性并没有取得甲基化的成功；通过不同的方法将C3-羰基掩蔽，但是C8-羰基的烯醇化依然无法抑制；虽然通过将呋喃环转化为α，β-不饱和-γ-丁内酯可以抑制烯醇化，但内酯环上的双键迁移又成了新的竞争反应。

ABSTRACT with Huangdi's Internal Classic and a great deal of clinic verification,indorctrinate for foundation,combine the nerve,the meridian electromagnetism field and the quantum physics to the new detection that realizes a function of thought outside body, argument The main mechanism of the method of reinforcing-reduucing in Huangdi's Internal is to promoting-reduucing Qi with doctor's thought,the very few entwist and turn;Discover new the method of reinforcing-reduucing mechanism, to many repaired basic standpoints of the reinforcing-reduucing to all do all new hermeneutic combine in the clinic and can verify, and unify to named after"acupuncture of promoting Qi with thought ".

以《内经》及大量的临床验证为基础，结合神经、经络电磁场及量子物理学对意识在体外作用的新发现，论证了《内经》针刺补泻的主要动力是医者的以意行气，极少捻转；对许多补泻基本观点做了全新的解释并在临床中得以验证，发现了新的针刺机理，并统一命名为&意气针灸疗法&。

Receiving signals from any kinds of cascades, a number of transcription factors have been implicated as direct mediators of hypertrophic gene expression including SPl, Elk-1, SRF, MEF-2, GATA, and LIM proteins.

目前虽然认为心肌肥大的发病机制与细胞外的心肌肥大因子刺激、细胞内的信号转导和核内的某些基因活化有关，但其最本质的特征是心肌细胞基因表达的异常。

Results:There were no abdominal pain and fever,jaundice faded away gradually postoperation.Biliary drainage was 300ml-1000ml/d more or less.Colour of bile changed into normal by degrees.Intra peritoneal drainage was open and the colour was light bloody.Amount of drainage dropped off day after day.Whole blood cell test, serum glutamic pyruvic transaminase,serum glutamic oxalacetic transarninase,total serum protein,serum albumin and serum globulin returned to normal in first week postoperation.Serum bilirubin,serum glutamyltranspetidase and serum alkaline phosphatase declined gradually in first week postoperation.T-tube was clipped at twelfth day postoperation.T-tube Cholangiography was clear at 24~ day postoperation.

结果：术后无上腹部绞痛、高热，黄疸逐渐减退，每日引流胆汁300ml-1000ml不等，由淡黄色混浊、内有胆泥过渡到金黄色清亮的正常胆汁，腹腔引流通畅，引流液为淡红色，量从最初的200ml迅速过渡到10ml，血常规、血清谷丙转氨酶、谷草转氨酶、总蛋白、白蛋白、球蛋白等1周内均恢复正常，血清总胆红素、直接胆红素、间接胆红素、谷氨酰转肽酶、碱性磷酸酶逐渐下降，术后12d夹闭T管，术后24d T管造影提示左、右肝管及胆总管下端通畅，无狭窄。

Twenty-two aged patients of chronic urinary infection were treated with intracullar poly-saccharide of Polystictus versicolarFr.. Patients were divided into 3 groups: group A(10cases)was given I and antibiotic, group B (5 cases) recieved I and group C (7 cases) served as control.

本文报道云芝孢内多糖治疗老年慢性尿路感染15例及血清补体水平低下者41例结果，尿路感染患者云芝孢内多糖加抗菌药物合用组，尿培养阴转率达80％，近期疗效较单用组和对照组为满意。

The introduced techniques include changing the state of firebox in lamellar sample and the state of the sample in firebox, changing oxygen pressure in firebox and adjusting operation mode of rotating key which controls the electrical current of portfire.

该文分析了燃烧热测定实验常见的失败原因，并针对其中的主要原因，提出了 4点改进方法，即改变燃烧丝在片状药品中的状态和位置，改变药片在氧弹内坩埚中的状态，改变氧弹内氧气的压力值和改变点火电流控制转钮的操作方式。

In the negative and interrogative forms, of course, this is identical to the non-emphatic forms.

。但是，在否定句或疑问句里，这种带有"do"的方法表达的效果却没有什么强调的意思。

Go down on one's knees;kneel down

屈膝跪下。。。下跪祈祷