内质的

Many studies have reported that Klebsiella pneumoniae is associated with ankylosing spondylitis but the mechanism of pathogenesis is remained unclear. The endoplasmic reticulum stress would be induced upon exposure of decapsulated KP in HLA-B27 expression B lymphoblast CA46 cells and non-HLA-B27 expression U937 monocytes. Our previous studies demonstrated that decapsulated KP could up-regulate BiP/Grp78 and calreticulin expressions in a dose- and time-dependent manner. We screen more than 60 kinds of traditional herbs and bioactivity agents and we found that berberine,taurine,extracts of Andrographis paniculata Nees.

许多研究指出克雷伯氏肺炎杆菌和僵直性脊椎炎有相当的关系，但是致病机制仍然不是很清楚，因此我们使用去荚膜克雷伯氏肺炎菌来诱发表现HLA-B27的CA46 B淋巴球母细胞、不含HLA-B27的U937单核球细胞可以产生内质网压力，我们先前的实验指出，随著剂量增加，去荚膜克雷伯菌能够过度调控内质网压力指标蛋白质BiP和Calreticulin表现增加。

Identification of GC: Distinctive ultramicrostructure of GC can be found by transmission electron microscope: tubiform chondrosome, SER and adipoid is abundant, and the quantity of GCs reach 80%-85%.

透射电镜下可看到所收集细胞中颗粒细胞达80％～85％，其特征性的超微结构：胞质内出现管状嵴线粒体，滑面内质网丰富，出现电子密度较高的类脂滴。

Endoplasmic reticulum is found in every cell and helps synthesize proteins and monitor how they're folded.

每一细胞中都有内质网的存在，内质网帮助合成蛋白质并监视蛋白质的折叠。

Results Microscopically, different degrees of hepatocytic degenerative changes and hyperplasic fibrous tissue and typical false lobule formation could be seen. Timm's staining result showed uneven distributed black granular deposits in the hepatocytes. No specific PAS staining was observed. Utrastructurally, the mitochondria were increased in volume and dramatically different in shape. The number of lysomes were increased.

结果 光镜下肝细胞表现为不同程度的退行性变，胶原纤维增生以及典型假小叶形成；Timm's染色阳性，发现不均匀分布黑色颗粒或团块样物质沉积；PAS染色则普遍缺乏特异性染色；超微结构显示线粒体形态多样，体积增大，溶酶体增多，粗面内质网管腔扩张，附着核糖体的脱颗粒，以及胞质水肿，质膜溶解。

Increase the bone marrow cell component while reduce the fat component, abnormal the caryon and cytomembrane structure of bone marrow cell and stromal cell, enrich the ribose body, mitochondrion and rough surfaced endoplasmic reticulum in cytoplasm of several organs and tissues, embody abvious improvement of heart muscle, liver, immnune organs, incretory organs and sexual gland.

增加免疫介导型再障小鼠的骨髓细胞成分，减少脂肪成分。使骨髓细胞和基质细胞的细胞核和细胞膜结构趋于正常，使多种脏器组织的细胞浆内核糖体丰富，线粒体及粗面内质网发达。对心、肝、免疫器官、内分泌器官及性腺等亦有明显的改善作用。

Microglia is always considered to be a kind of most representative immune cell in the central nervous system.

小胶质细胞一向被认为是中枢神经系统中最有代表性的免疫细胞，生理情况下小胶质细胞占脑细胞总数的10％左右，其生理功能以吞噬清除细胞残骸为主，保证脑内内环境的稳定。

Methods Ampicillin inhibitionof E. coli Top10 pcs+ was tested at first, and then b-lactamase activity in periplasm was examined.

然后再使用抗生素抗性分析、b-内酰胺酶的酶活测定以及Western blot杂交技术，分析质粒编码的b-内酰胺酶从细胞质到细胞间质的分泌情况。

Electronic microscopic observations showed that the swollen mitochondria with cristae blurred appeared in some pyramidal cells. Some pyramidal cells showed degenerative changes with some disappeared endoplastic reticula and ribose nuclear protein and increased lysosomes. The amount of extends endothelial projections going to the lumen of capillaries were increased.

同时伴有超微结构的改变，如神经细胞线粒体肿胀，内质网扩张，染色质凝集成块状，毛细血管外间隙扩大，髓鞘变性坏死，微管排列紊乱，小胶质细胞有吞噬变性坏死的神经纤维成分等。

During sexual differentiation, mitochondria and smooth endoplasmic reticulum in cells of testis also increase in quantity, but it is less than that in ovary, they disintegrate after sexual differentiation. The big grana always exsist in course of sexual differentiation, but small grana don\'t appear.

分化时精巢细胞的超微结构显示线粒体和内质网数量也有增加，但不如分化中卵巢细胞的数量多，分化后线粒体和内质网解体，在整个分化过程中大颗粒一直存在，无小颗粒出现。

Synthesized all above, the heat and mass transfer of charge bed is discussed in detail. After choosing seriously the former study results in this field, a whole temperature range process model for firing iron ore pellets containing solid fuel is established as well as its software is edited. The main physical chemistry reaction process within pellets and the heat statement can be calculated exactly with the process as long as the physical and chemical parameters of raw material are obtained through basic experiments. After finding out the reason of"temperature hysteresis"and"heat inertia"of the experimental induration device, a new kind of experimental induration device is designed. The"temperature hysteresis"of hot gas flow in the new device is avoided.

综合以上对焙烧球团矿时球团矿内各种物理化学反应过程的分析与研究的结果，仔细地分析研究了球团矿料层中的传热质现象，认真筛选了前人对填充床的传热传质的研究结果，提出了全温度范围球团矿焙烧过程模型，并编制了相应的计算机软件，只要通过基础实验，获得原燃料的基本物性参数（如化学反应速度常数，矿粉、煤粉的粒度及此表面积以及球团矿的导热性等），利用这一软件就能准确地计算出焙烧球团矿时球团矿内各种物理化学反应过程和料层内的热工状态。

The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了，排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意，我建议我们在价格上大家各让一半。