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It is widely accepted that AP depolarize the plasma membrane and open voltage-dependent calcium channels , the calcium influx through VDCCs trigger the fusion of vesicles with plasma membrane and subsequent transmitter release.

现在被普遍接受的观点是当可兴奋细胞受到动作电位的刺激后,细胞的电压依赖性钙离子通道被打开,在动作电位的下降相引起细胞外钙离子的内流从而升高细胞内的游离钙离子浓度,触发许多细胞内的过程,譬如说神经递质分泌、信号转导和基因表达等。

As the new medication-adjuvant,liposome has been widely applied in medication technology.

尽管脂质体这种新技术在生物领域内具有极其广阔的应用前景,但脂质体在该领域的研究应用中存在着较多的技术难题。

The physicochemical properties, fatty acid composition and mineral elements of Viburnum cylindricum seed oil were determined. The results showed that 20 kinds of fatty acids in the Viburnum cylindricum seed oil were identified, in which the main components were oleic acid (33.34%), 8,11-octadecadienoic acid (28.24%) and palmitic acid (22.55%); the seed oil contained 6 kinds of essential mineral elements including Ca, P, Mg, Fe, K and Mn, and their contents were in the reasonable range of body requirement.

测定了水红木油的理化指标;用GC/MS法测定了脂肪酸组成及含量,共检出20种脂肪酸,主要成分9-十八碳烯酸占33.34%,8,11-十八碳二烯酸占28.24%,十六烷酸占22.55%,3种脂肪酸共占84.13%;用ICP-OES法测定了矿质元素的种类和含量,检出的Ca、P、Mg、Fe、K、Mn 6种矿质元素均为人体必需元素,含量均在人体所需合理范围内。

Objective To explore the protective effect of idazoxan on the experimental autoimmune encephalomyelitis in Lewis rats and its effect on the change of microglia and astroglia in cervical cord and the expression of IFN-γ/IL-10 in serum.

目的 探讨咪唑克生(Idazoxan,Ida)对Lewis大鼠实验性自身免疫性脑脊髓炎(Experimental Autoimmune Encephalomyelitis, EAE)的干预作用,观察其对大鼠脊髓组织内小胶质细胞、星形胶质细胞的变化和血清IFN-γ/IL-10表达的影响。

Results: The study showed that the earliest stromal nodules were fibrous, and with the dual differentiation of myofibroblasts toward both smooth muscle cells and fibrous cells, they developed into fibromyomatous nodules and muscular nodules. The results of reclassifying the 55 nodules immunohistochemically were that 23(42%) was fibrous, 28(51%) fibromuscular nodules and 4(7%) muscular.

结果:结合HE切片和免疫组化结果发现前列腺间质结节的早期为幼稚的纤维性结节,随着结节内肌纤维母细胞向平滑肌细胞和纤维细胞的双向分化,间质结节可继续演化为纤维肌性结节和肌性结节。55个结节按免疫组化分类,纤维性结节占42%,纤维肌性结节占51%,肌性结节占7%。

Gliosis plays a critical role in post-traumatic epileptogenesis. The inhibition of the proliferation of astrocytes with 7β OHCH could influence synaptic plasticity, modulate the imbalance of excitatory and inhibitory systems in hippocampus and postpone the latency between injury and the occurrence of chronic spontaneous seizures, furthermore to some extent, reduce the occurrence of post-traumatic epilepsy.

星形胶质细胞增生在创伤性癫痫发病机制中起重要作用,抑制胶质细胞增生,可影响海马突触可塑性,有利于调整海马内兴奋性和抑制性功能系统之间作用的失衡,可延长损伤与发生慢性自发性抽搐之间的间歇期,在一定程度上降低创伤性癫痫的发病率。

Results The intramural capillary lymphatics of rat's rectum were observed in deep lamina propria of tunica membrane and the dermal papilla layer of anal pectin. The intramural capillary lymphatics and lymphatics were both observed in tela submucosa, reticular layer, hypodermis and intermuscular and serosa. The capillary lymphatics in rectums' wall have the similar ultrastructure feature to normal ones. Three kinds of endothelial cells junctions are overlapping junctions, embedding-junctions and end to-end-type junctions. About 21% of cell-junctions are opening types. There are normal organelles and many vesicals in the endothelial of capillary lymphatics.

结果 直肠壁内的毛细淋巴管见於黏膜固有层深部和肛梳区真皮乳头层;在黏膜下层和肛梳区的网状层、皮下组织以及肌层和浆膜层内均有毛细淋巴管和淋巴管,直肠壁内毛细淋巴管的超微结构具有一般毛细淋巴管超微结构的特点,内皮细胞连接有重叠、嵌插和端端连接3种类型,处於开放状态约占21%;胞质内含有一般的细胞器,幷含有大量的囊泡。

Spikelets laterally compressed, lanceolate-oblong, florets several, contiguous; rachilla scaberulous, disarticulating above glumes and between florets; glumes slightly unequal, upper nearly as long as spikelet, firmly membranous, keel scaberulous, apex abruptly acuminate, lower glume 1–3-veined, upper glume 3–5-veined; lemmas broadly lanceolate, thinly leathery, rounded on back, 5–7-veined, veins smooth, not raised, scabrid above middle, apex scarious, usually 3-denticulate, sometimes mucronate; floret callus subacute, bearded laterally with stiff hairs; palea subequal to lemma, narrow, flat, apex sharply 2-denticulate.

小穗侧面压扁,披针形长圆形,小花数个,邻接;小穗轴高于颖片微糙,脱节和在小花之间;颖片稍不等长,上面近等长小穗,坚定膜质,龙骨状,先端突然渐尖,下部颖片1-3,上面颖片3-5-脉;宽披针形的外稃,在背面上薄革质,圆形,5-7-脉,平滑的脉,不凸起,在中部以上,先端,通常3-具小齿,小花结茧稍尖,用硬的头发侧面公然反对;内稃近等长于外稃,缩小,平,顶明显2-具小齿。

The clue is the prominent eosinophilic and hyalinized so-called "glassy membrane" band in between dark spindle granulosa layer and lutinized theca interna. There are scattered lutinized thecal cells in theca interna with ample pink cytoplasm which are usually seen in childhood or pregnancy.

诊断线索是明显的嗜酸性胞质和位于暗梭形颗粒细胞层和黄素化卵泡膜之间的透明化的所谓&透明膜&带,在卵泡膜内层有散在黄素化卵泡膜细胞,胞质淡粉染,这种细胞常见于儿童期或孕期。

We biopsied 1-2 single blastomere from 6-8 cell cleavage stage intracytoplasmic sperm injection embryo, and using nested PCR amplified the high frequently mutation region G380R of FGFR3 gene of the single blastomere. The products of PCR were digested by restriction enzyme Bfm Ⅰ, then the digested products were detected by 10% PAGE to see whether the embryo inherted the mutation of the patient and to screen out normal embryo transfer.

活检经胞质内单精子注射(intracytoplasmic sperm injection,ICSI)授精的胚胎发育至6~8细胞期的1~2个单卵裂球,采用巢式PCR扩增单卵裂球的FGFR3基因的高发突变位点G380R区域,用限制性内切酶BfmⅠ消化巢式PCR的内扩增产物,再经10%聚丙烯酰胺凝胶电泳检测有无遗传患者的该种突变,从而筛选出正常胚胎移植。

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The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了,排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意,我建议我们在价格上大家各让一半。

After an hour and no pup, look for continued contractions and arching of the back with no pup as a sign of trouble.

一个小时后,并没有任何的PUP ,寻找继续收缩和拱的背面没有任何的PUP作为一个注册的麻烦。