内质

The typical apoptotic morphological features appeared in MUTZ1 cells treated with 4 mmol/L VPA for 72 hours. Pyknosis of cells and nuclei, disintegration of nuclear chromatin and apoptotic body could be observed by light microscopy. Aggregation and margination of nuclear chromatin, concentration of plasm, increment of density and chromatin mass of irregular size could be observed by transmission electronmicroscope. The flow cytometric analysis indicated that the VPA could induce cell apoptosis, apoptosis rate increased in dosedependent manner, ratio of cells at G0/G1 phase increased and ratio of cells at S phase decreased in dosedependent manner, the cells were arrested at G0/G1 phase.

结果显示： VPA对MUTZ1细胞的生长抑制作用呈现时间和剂量依赖性；经4 mmol/L VPA处理MUTZ1细胞72小时后，细胞呈现典型的凋亡形态特征，光学显微镜下可见凋亡细胞胞体固缩、核固缩、核碎裂及凋亡小体；透射电子显微镜下可见凋亡细胞核染色质边集、胞浆浓缩、密度增加，胞浆内大小不规则的染色质团块；流式细胞术结果表明，细胞凋亡率随着VPA浓度的增加而逐步增高，G0/G1期细胞比例随着VPA浓度的增加而逐渐增多，S期细胞比例逐渐减低，细胞被阻滞在G0/G1期。

The typical apoptotic morphological features appeared in MUTZ-1 cells treated with 4mmol/L VPA for 72hours. Pyknosis of cells and nuclei, disintegration of nuclear chromatin and apoptotic body could be observed by light microscopy. Aggregation and margination of nuclear chromatin, concentration of plasm, increment of density and chromatin mass of irregular size could be observed by transmission electronmicroscope. The flow cytometric analysis indicated that the VPA could induce cell apoptosis, apoptosis rate increased in dose-dependent manner, ratio of cells at G0/G1 phase increased and ratio of cells at S phase decreased in dose-dependent manner, the cells were arrested at G0/G1 phase.

结果显示：VPA对MUTZ-1细胞的生长抑制作用呈现时间和剂量依赖性；经4mmol/LVPA处理MUTZ-1细胞72小时后，细胞呈现典型的凋亡形态特征，光学显微镜下可见凋亡细胞胞体固缩、核固缩、核碎裂及凋亡小体；透射电子显微镜下可见凋亡细胞核染色质边集、胞浆浓缩、密度增加，胞装内大小不规则的染色质团块；流式细胞术结果表明，细胞凋亡率随着VPA浓度的增加而逐步增高，G0/G1期细胞比例随着VPA浓度的增加而逐渐增多，S期细胞比例逐渐减低，细胞被阻滞在G0/G1期。

For Goupitan Hydropwer Station on Wujiang River,over 1 200 anti-uplift anchor pile s are arranged in the water cushion pool to anchor the non-uniform soft rock strata composed of shale,clay rock,silty clay rock,thin layer of marlite and less medium-fine calcareous sandstones etc.

乌江构皮滩水电站水垫塘部位布置了1200多根抗浮锚桩，对页岩、粘土岩、粉砂质粘土岩，及夹薄层泥灰岩和少量中细粒钙质砂岩等不均质软岩层软岩进行锚固，原设计锚桩的间距为2.2m，为了优化设计，缩短工期，在施工前进行了4根锚桩原位抗拔试验，根据锚桩在抗拔过程中周边一定范围内岩体变形沿径向的分布规律，及破坏时裂隙的扩展形态和范围，确定了锚桩的间距，在此基础上提出了锚桩间距的优化方案，并应用于工程施工。

The matrix metalloproteinases are a group of zinc-dependent endopeptidase with homogenous structure and function; it can degrade various components of the extracellular matrix.

基质金属蛋白酶是结构和功能同源的一组锌离子依赖的内肽酶家族，能降解细胞外基质的多种成分。

The method can be used in all kinds of domains since it calculates the global minimum of a constrained multi-extrema function to get high-quality centroidal Voronoi tessellations for the region.

该算法结合k-means方法和模拟退火算法求解约束条件下的多峰值函数全局最小值，在待求计算域内和边界自动生成无网格计算节点，且节点为计算域对应质心Voronoi结构的质心点。

Astrocytes constitute nearly half of the cell in brain, but its funtion is a long-standing neurobiological mystery.

星形胶质细胞是脑内数量最多的一类胶质细胞，与神经系统生长发育，功能活动及疾病的形成有密切关系。

So it is believed that agmatine may serve as a novel neurotransmitter and/or neuromodulator.

因而，普遍认为胍丁胺可能是脑内一种新的神经递质和/或调质。

Histological structures of bursas of Fabricius were observed at the different developmental stages from chicken embryoes to chickens. The results were as follows. The bursa of Fabricius began to develop on the 13th day of post-hatching and its cell aggregated into the nodosity clique underneath the epithelium mucosae. On the 15th day of post-hatching, those cell cliques were surrounded by the flat epithelium and formed the basic structure of folliculus lymphaticus. The number of lymphocytes in the folliculus lymphaticus increased gradually, and the medulla and cortex of a majority of folliculus were not discriminated obviously. Until on the 7th day for chickens, the medulla and cortex of folliculus formed completely and the number of folliculus increased significantly. From 21 to 35 days old, the folliculus lymphaticus transformed from polygon into rectangle. Mucosa epithelial cells increased gradually and their cytoblasts arranged compactly into aline in the basilar part on the 35th day.

本研究观察了从鸡胚到出壳后的不同生长发育阶段法氏囊的组织结构，结果表明：胚胎13日龄时，法氏囊开始发育，粘膜上皮下形成结节状细胞集团；胚胎15日龄，聚集的细胞集团形成初始的淋巴滤泡；胚胎18日龄到出壳后1日龄，滤泡内淋巴细胞数量增多，多数滤泡髓质和皮质界限仍不明显；7日龄雏鸡法氏囊髓质皮质分界清晰，滤泡数量显著增多；21日龄到35日龄，滤泡由多边形逐渐转变成长方形；在35日龄时，粘膜上皮细胞逐渐增多，排列紧密，细胞核紧密排列成直线位于基底部。

There were more Ca〓 deposite granules in and around the condensing granules of nucleoplasm; 2 There were large amount of Ca〓 in the Golgi complex of spermatid in Golgi phase. The Ca〓 in the acrosomal vesicle were probably from the Golgi complex; 3 Ca〓 was probably concerned with adherence of the acrosomal vesicle to the nuclear membrane.

发现（1）。Ca〓与精子形成过程中染色质的致密化有关，圆形精子细胞局部致密化的染色质团块周围及其内部和长形精子处于的致密化过程的核内均具有较多的Ca〓；（2）。

To explore the functions of SPANXA1 in cancerous phenotypes CL1-5 cells were transfected with a SPANXA1 expressing vector and evaluated by cell proliferation, cell migration, Matrigel invasion and colony formation assays in vitro as well as mouse metastasis assays in vivo. The results indicated that the induction of SPANXA1 could reduce cell invasiveness. In the other hand, immunostaining showed that SPANXA1 was predominately located at the nucleoplasm.

经RT-PCR验证得知SPANXA1在CL1-0的表现量比CL1-5多100倍以上，於是我们将SPANXA1转染在CL1-5细胞株中，并测量活体外的细胞生长速度试验、细胞迁徙实验、Matrigel侵袭实验、癌细胞群落形成实验及小鼠活体内细胞转移能力，探讨SPANXA1对癌细胞性状的影响，结果发现增加SPANXA1会降低癌细胞的转移能力，在另一方面，我们利用免疫萤光染色法侦测出SPANXA1是存在於核质中，并以西方点墨法再次证实SPANXA1是存在於核质中。

The labia have now been sutured together almost completely.The drains and the Foley catheter come out at the top.

此刻阴唇已经几乎完全的缝在一起了，排除多余淤血体液的管子和Foley导管从顶端冒出来。

To get the business done, I suggest we split the difference in price.

为了做成这笔生意，我建议我们在价格上大家各让一半。