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Oligomenorrhea for six or more months or an episode of heavy dysfunctional bleeding is an indication for endometrial surveillance.

月经稀发发生6个月或以上,或者发生严重的功能性子宫出血是进行子宫内膜检查的指征。

Oligomenorrhea for six or more months or an episode of heavydysfunctional bleeding is an indication forendometrial surveillance.

月经稀发发生6个月或以上,或者发生严重的功能性子宫出血是进行子宫内膜检查的指征。

Results 80 cases of female pelvic masses,among them 8 cases ectopic pregnancy,16 cases leiomyoma of uterus,12 cases ovarian cyst,10 cases teratoma of ovary,12 cases oophoroma,8 cases ondometrial carcinoma and 12 cases cases cervical carcinoma.

结果 80例女性盆腔包块,其中异位妊娠8例,子宫平滑肌瘤16例,卵巢囊肿12例,卵巢畸胎瘤10例,卵巢癌14例,子宫内膜癌8例,宫颈癌12例。

Results 80 cases of female pelvic masses,among them 8 cases ectopic pregnancy,16 cases leiomyoma of uterus,12 cases ovarian cyst,10 cases teratoma of ovary,12 cases oophoroma,8 cases ondometrial carcinoma and 12 cases cases cervical carcinoma.

功效 80例女性盆腔包块,其中异位妊娠8例,子宫平滑肌瘤16例,卵巢囊肿12例,卵巢畸胎瘤10例,卵巢癌14例,子宫内膜

Results:60 cases of female pelvic masses, among them, 4 cases ectopic pregnancy,8 cases ovarian cyst,12 cases oophoroma,8 cases teratoma of ovary,6 cases endometrial carcinoma,10 cases cervical carcinoma and 12 cases leiomyoma of uterus.The accuracy rate of CT diagnosis was 90.00% and ultrasound diagnosis was 86.67%.

结果:60例女性盆腔肿块,其中宫外孕4例,卵巢囊肿8例,卵巢癌12例,卵巢畸胎瘤8例,子宫内膜癌6例,宫颈癌10例,子宫平滑肌瘤12例,CT符合率为90.00%,B超符合率为86.67%。

In the procedure, two cases with branches ostial lesion appeared dissection and stent was implanted, the remained stenosis ratio was 10%~50%. The SafeCut balloon success rate was 100%, and no hospitalized complications such as acute myocardial infarction occurred.

对分支血管行SafeCut球囊扩张后有2例因内膜严重撕裂而置入支架,其余病变残余狭窄为10%~50%,成功率达100%,无急性心肌梗死等严重并发症。

All the results indicated:the molecular mechanism for embryoes abortion mediated by calcium may be relevant to some genes, which controlling assenergy transfering oxidoreduction system endomembrane system and cytoskeleton structure system ,transcripted or expressed unnomally.

由以上研究结果初步可以认为:受钙胁迫花生幼胚败育的分子机理可能是与早期幼胚内与能量转化、氧化还原系统运转、细胞内膜以及细胞骨架功能维持相关的功能基因的转录和表达异常有关。

There are four kind of isoforms of endothelin in human and other mammals named ET-1, ET-2, ET-3 and ET-β, which are slightly different in construction and pharmacological effect. In human beings, ET-1 is the dominative subtypes. ET-1 remains in blood at a low level about 5ng per liter on physical state. It is synthesized, stored, released and metabolized locally. The half-life of ET-1 is about 1 hour. ET-1 is the most potent vasoconstrictive factor till now, and it is more functional in vein than in artery. In vascular bed, there are two kind of ET receptors. Type A mainly located in smooth muscle cells, whereas type B in endothelial cells. The latter can stimulate intimal hyperplasia via a parasecretion way and activate some oncogenes such as c-fos and c-myc and then enhance their expression. These alterations result in constriction of blood vessels, thus the SMC steps into proliferate state from silent state.

人及哺乳动物体内有四种结构及药理学性质略有差异的异物体,分别为ET-1、ET-2、ET-3、ET-β,而在人主要是ET-1,在生理条件下,ET-1在血浆中含量较低,约为5ng〓,故ET-1不是一个循环激素,而是局部合成释放,局部起作用的活性物质,半衰期约1小时,ET-1是目前已知的最强的血管收缩剂,对静脉的作用比动脉强,在血管床,ET受体有A、B两型,A型主要分布在平滑肌细胞,B型主要分布在内皮细胞,它可以通过旁分泌途径刺激内膜增生,具有有丝分裂原效应,可以激活某些癌基因如C-fos、C-myc使其表达增强引起血管收缩,使静止期SMC进入增殖期,还可以通过信号传导途径,与bFGF、GTF-β、PDGF等生长因子协同作用,起共有丝分裂原作用。

Abnormal expression of PTEN gene was involved in progression of ovarian cancer probably by decreasing cell adhesion and apoptosis, increasing cell mobility and angiogenesis. Reduced expression of PTEN gene was closely associated with tumorigenesis and pathobiological behavior of ovarian endometrioid cancer.

PTEN蛋白表达下调与卵巢恶性肿瘤的组织分化程度、临床病理分期和转移能力相关,与卵巢癌中的子宫内膜样癌PTEN蛋白表达关系更为密切。

Down-regulated expression of PTEN and up-regulated expression of VEGF〓 were considered as two important events in tumorigenesis of ovarian cancer and could act as molecular markers to indicate the pathobiological behaviors of ovarian cancer. Decreased PTEN expression and increased VEGF〓 expression were closely associated with tumorigenesis and pathobiological behaviors of ovarian endometrioid and serous cancer respectively. Reduced expression of PTEN gene might be involved in carcinogenesis and progression of ovarian cancer by up-regulating the VEGF〓 expression to enhance angiogenesis.

在卵巢癌组织中PTEN基因mRNA表达下调和VEGF〓基因mRNA表达上调是卵巢癌发生的重要分子事件,可作为反映卵巢癌病理生物学行为的指标,且分别与卵巢内膜样癌和浆液性囊腺癌的发生和病理生物学行为关系密切;PTEN基因mRNA表达降低可能通过上调VEGF〓基因mRNA表达促进新生血管形成,进而参与卵巢癌的发生和侵袭。

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